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KCNS1 (KV9.1) (extracellular) Antibody (APC-131-200UL) in WB
Western blot analysis of mouse (lanes 1 and 4), and rat (lanes 2 and 5) brain membranes and human HL-60 promyelocytic leukemia cell lysates (lanes 3 and 6): - 1-3. Anti-KCNS1 (KV9.1) (extracellular) Antibody (#APC-131), (1:200).4-6. Anti-KCNS1 (KV9.1) (extracellular) Antibody , preincubated with KCNS1/Kv9.1 (extracellular) Blocking Peptide (#BLP-PC131).
Product Details
APC-131-200UL
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
(C)EDVRDDPVLRRLE, corresponding to amino acid residues 233-245 of rat KCNS1, 1st extracellular loop
Conjugate
Form
Lyophilized
Concentration
0.8 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitution: 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Target Information
Voltage-gated potassium channels form the largest and most diversified class of ion channels and are present in both excitable and nonexcitable cells. Their main functions are associated with the regulation of the resting membrane potential and the control of the shape and frequency of action potentials. The alpha subunits are of 2 types: those that are functional by themselves and those that are electrically silent but capable of modulating the activity of specific functional alpha subunits. The KCNS1 protein is not functional by itself but can form heteromultimers with member 1 and with member 2 (and possibly other members) of the Shab-related subfamily of potassium voltage-gated channel proteins. KCNS1 belongs to the S subfamily of the potassium channel family.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Delayed-rectifier K(+) channel alpha subunit 1; Delayed-rectifier potassium channel regulatory subunit KCNS1; Delayed-rectifier potassium channel subunit Kv9.1; hKv9.1; K+ voltage-gated channel, subfamily S, 1; Potassium voltage-gated channel modifier subfamily S member 1; potassium voltage-gated channel subfamily S member 1; potassium voltage-gated channel, delayed-rectifier, subfamily S, member 1; potassium voltage-gated channel, modifier subfamily S, member 1; voltage-gated potassium channel subunit Kv9.1
Gene Aliases: KCNS1; Kv9.1
UniProt ID: (Human) Q96KK3, (Mouse) O35173, (Rat) O88758
Entrez Gene ID: (Human) 3787, (Mouse) 16538, (Rat) 117023
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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