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Product Details
PA5-99644
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human KCNT1(Accession Q5JUK3), corresponding to amino acid residues I1019-G1069.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2818577
Product Specific Information
Antibody detects endogenous levels of total KCNT1.
Target Information
Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a sodium-activated potassium channel subunit which is thought to function in ion conductance and developmental signaling pathways. Mutations in this gene cause the early-onset epileptic disorders, malignant migrating partial seizures of infancy and autosomal dominant nocturnal frontal lobe epilepsy. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: KCa4.1; KCa4.1KIAA1422FLJ41282; KNa1.1; Potassium channel subfamily T member 1; potassium channel subunit (Slack); potassium channel, sodium activated subfamily T, member 1; potassium channel, subfamily T, member 1; Sequence like a calcium-activated K+ channel; Sequence like a calcium-activated potassium channel subunit; Slo2.2; Sodium and chloride-activated ATP-sensitive potassium channel Slo2.2
Gene Aliases: bA100C15.2; C030030G16Rik; EIEE14; ENFL5; KCa4.1; KCNT1; KIAA1422; rSlo2; SLACK; slo2; Slo2.2
UniProt ID: (Human) Q5JUK3, (Mouse) Q6ZPR4, (Rat) Q9Z258
Entrez Gene ID: (Human) 57582, (Mouse) 227632, (Rat) 60444
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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