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KCTD11 Antibody (PA5-142626) in WB
Western Blot analysis of KCTD11 in HEK293 lysate (10 µg protein in RIPA buffer) using KCTD11 Polyclonal Antibody (Product # PA5-142626) at 1.0 µg/mL. Lane A: HEK293 lysate over expressing Human KCTD11 with DYKDDDDK tag probed with KCTD11 Antibody. Lane B: Mock-transfected HEK293 probed with KCTD11 Antibody. Lane C: HEK293 lysate over expressing Human KCTD11 with DYKDDDDK tag probed with anti-DYKDDDDK Tag (1:5,000). Primary incubations were for 1 hour. Detected by chemiluminescence.
Product Details
PA5-142626
Product Specifications
Species Reactivity
Human
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide with sequence C-PEVEYGRLGLQP.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Ammonium sulfate precipitation
Storage buffer
TBS, pH 7.3, with 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2933272
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:16,000.
Target Information
Calponin, a thin filament associated protein is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. Calponin is expressed in smooth muscle and tissues containing significant amounts of smooth muscle. Two isoforms of calponin exist whose molecular weights are 34kDa and 29kDa. Expression of the 29kDa form is primarily restricted to muscle of the urogenital tract. The expression of calponin has also been demonstrated in myoepithelial cells from benign and malignant breast lesions. It stains smooth muscle, myoepithelial cells, myofibroblasts, keratinocytes and nerve fibers. It identifies myoepithelial cells in breast lesions, and helps differentiate breast collagenous spherulosis (positive) from adenoid cystic carcinoma. Adenoid cystic carcinoma in salivary gland tumors is calponin positive.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BTB/POZ domain-containing protein KCTD11; KCASH1 protein; potassium channel tetramerisation domain containing 11; Potassium channel tetramerization domain-containing protein 11; retinoic acid, EGF, NGF induced gene protein; retinoic acid, EGF, NGF induced gene/potassium channel tetramerization domain containing 11; RING-type E3 ubiquitin transferase subunit KCTD11
Gene Aliases: C17orf36; KCASH1; KCTD11; REN; REN/KCTD11
UniProt ID: (Human) Q693B1
Entrez Gene ID: (Human) 147040
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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