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Product Details
H00079734-B01P
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KCTD17 (NP_078957.1, 1 a.a. approximately 290 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MRMEAGEAAP PAGAGGRAAG GWGKWVRLNV GGTVFLTTRQ TLCREQKSFL SRLCQGEELQ SDRDETGAYL IDRDPTYFGP ILNFLRHGKL VLDKDMAEEG VLEEAEFYNI GPLIRIIKDR MEEKDYTVTQ VPPKHVYRVL QCQEEELTQM VSTMSDGWRF EQLVNIGSSY NYGSEDQAEF LCVVSKELHS TPNGLSSESS RKTKSTEEQL EEQQQQEEEV EEVEVEQVQV EADAQEKGSR PHPLRPEAEL AVRASPRPLA RPQSCHPCCY KPEAPGCEAP DHLQGLGVPI
Target Information
Is a positive regulator of ciliogenesis, playing a crucial role in the initial steps of axoneme extension. It acts as a substrate-adapter for CUL3-RING ubiquitin ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of TCHP, a protein involved in ciliogenesis down-regulation (PubMed:25270598). May be involved in endoplasmic reticulum calcium ion homeostasis (PubMed:25983243).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BTB/POZ domain-containing protein KCTD17
Gene Aliases: KCTD17
UniProt ID: (Human) Q8N5Z5
Entrez Gene ID: (Human) 79734
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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