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Immunogen sequence: MGAVMGTFS SLQTKQRRPS KDKIEDELEM TMVCHRPEGL EQLEAQTNFT KRELQVLYRG FKNECPSGVV NEDTFKQIYA QFFPHGDAST YAHYLFNAFD TTQTGSVKFE DFVTALSILL RGTVHEKLRW TFNLYDINKD GYINKEEMMD IVKAIYDMMG KYTYPVLKED TPRQHVDVFF QKMDKNKDGI VTLDEFLESC QEDDNIMRSL QLFQNVM (1-216 aa encoded by BC050375)
This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. Alternative splicing results in multiple transcript variant encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: A-type potassium channel modulatory protein 1; A-type potassium channel modulatory protein KCNIP1; ABP; KChIP1; KCHIP2; Kv channel interacting protein 1; Kv channel-interacting protein 1; potassium channel interacting protein 1; Potassium channel-interacting protein 1; Vesicle APC-binding protein
Gene Aliases: KCHIP1; KCNIP1; VABP
UniProt ID: (Human) Q9NZI2
Entrez Gene ID: (Human) 30820
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