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Invitrogen
KDEL Receptor Pan Monoclonal Antibody (KR-10)
Product Details
MA1-90944
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Rabbit,
Rat,
Xenopus,
Bovine,
Dog,
Chicken,
Fruit fly,
Hamster,
Human,
Mouse,
Non-human primate,
Sheep,
Pig
Published species
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
KR-10
Immunogen
Peptide corresponding to aa 192-212 of bovine KDEL receptor conjugated to KLH.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_1956085
Product Specific Information
Store as a concentrated solution. Centrifuge briefly prior to opening vial.
Target Information
Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu (KDEL) in animal cells, and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the tetrapeptide-containing protein, and returns it to the ER. In yeast, the sorting receptor encoded by a single gene, ERD2, which is a seven-transmembrane protein. Unlike yeast, several human homologs of the ERD2 gene, constituting the KDEL receptor gene family, have been described. The protein encoded by this gene was the first member of the family to be identified, and it encodes a protein structurally and functionally similar to the yeast ERD2 gene product.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2; CG5183-PA; CG5183-PB; CG5183-PC; ELP-1; ER lumen protein retaining receptor; ER lumen protein retaining receptor 1; ER lumen protein retaining receptor 2; ER lumen protein retaining receptor 3; ER lumen protein-retaining receptor; ER lumen protein-retaining receptor 1; ER lumen protein-retaining receptor 2; ER lumen protein-retaining receptor 3; ERD-2-like protein; ERD2-like protein 1; ERD23; KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1; KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2; KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2-like; KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3; KDEL endoplasmic reticulum protein retention receptor 1; KDEL endoplasmic reticulum protein retention receptor 2; KDEL endoplasmic reticulum protein retention receptor 3; KDEL receptor; KDEL receptor 1; KDEL receptor 2; KDEL receptor 3; KDEL receptor 3-like; KDEL-receptor; KdelR-PA; KdelR-PB; KdelR-PC; lethal (2) 31Em; Putative MAPK-activating protein PM23
Gene Aliases: 1110007A14Rik; 8030486F04Rik; AI173274; AW215843; BEST:CK00230; BOS_17737; BOS_23003; BOS_6123; CG5183; CK00230; Dmel\CG5183; Dmel_CG5183; dmErd2; ELP-1; ERD2; ERD2.1; ERD2.2; ERD23; ERD2L3; ergr15; HDEL; I79_001653; I79_020931; I79_023963; KDELR; KDELR1; KDELR2; KDELR3; l(2)31Em; l(2)k00311; PM23; RCJMB04_8l23; XELAEV_18045328mg
UniProt ID: (Bovine) P33946, (Human) P24390, (Bovine) Q2KJ37, (Human) P33947, (Chicken) Q5ZKX9, (Human) O43731, (Fruit fly) O76767, (Mouse) Q99JH8, (Rat) Q569A6, (Mouse) Q9CQM2, (Rat) Q5U305, (Mouse) Q8R1L4, (Xenopus) Q7ZXS5
Entrez Gene ID: (Bovine) 618184, (Sheep) 101122047, (Human) 10945, (Dog) 484406, (Bovine) 531676, (Human) 11014, (Chicken) 771927, (Dog) 612839, (Sheep) 101116624, (Chicken) 418026, (Dog) 474509, (Pig) 100514523, (Sheep) 101121418, (Bovine) 509687, (Human) 11015, (Fruit fly) 34427, (Chinese hamster) 100750912, (Mouse) 68137, (Rat) 361577, (Mouse) 66913, (Rat) 304290, (Chinese hamster) 100765889, (Mouse) 105785, (Chinese hamster) 100750636, (Rat) 315131, (Rabbit) 100338388, (Rabbit) 100338871, (Rabbit) 100349892, (Xenopus) 380330
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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