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KDM1B Antibody (CL488-67886) in Flow
1X10^6 SW 1990 cells were intracellularly stained with 0.4 µg CoraLite® Plus 488 Anti-HUMAN KDM1B (CL488-67886, Clone:1E1A3) (red), or 0.4 µg Control Antibody. Cells were fixed and permeabilized with Transcription Factor Staining Buffer Kit (PF00011).
Product Details
CL488-67886
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
1E1A3
Immunogen
Recombinant protein
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Purification
Protein A
Storage buffer
PBS with 50% glycerol, 0.5% BSA
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: FPYRFWDSKV QGADFFGHVP PSASKRGLFA VFYDMDPQKK HSVLMSVIAG EAVASVRTLD DKQVLQQCMA TLRELFKEQE VPDPTKYFVT RWSTDPWIQM AYSFVKTGGS GEAYDIIAED IQGTVFFAGE ATNRHFPQTV TGAYLSGVRE ASKIAAF
Target Information
Flavin-dependent histone demethylases, such as KDM1B, regulate histone lysine methylation, an epigenetic mark that regulates gene expression and chromatin function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: amine oxidase (flavin containing) domain 1; amine oxidase, flavin containing 1; Flavin-containing amine oxidase domain-containing protein 1; lysine (K)-specific demethylase 1B; Lysine-specific histone demethylase 1B; Lysine-specific histone demethylase 2
Gene Aliases: 4632428N09Rik; AI482520; AOF1; bA204B7.3; C6orf193; dJ298J15.2; KDM1B; LSD2
UniProt ID: (Human) Q8NB78, (Mouse) Q8CIG3
Entrez Gene ID: (Human) 221656, (Mouse) 218214, (Rat) 306819
DNA binding
zinc ion binding
histone demethylase activity
histone demethylase activity (H3-dimethyl-K4 specific)
histone demethylase activity (H3-monomethyl-K4 specific)
flavin adenine dinucleotide binding
N-ethylmaleimide reductase activity
oxidoreductase activity
histone demethylase activity (H3-trimethyl-K4 specific)
reduced coenzyme F420 dehydrogenase activity
sulfur oxygenase reductase activity
malolactic enzyme activity
NADPH:sulfur oxidoreductase activity
metal ion binding
epoxyqueuosine reductase activity
molecular_function
regulation of gene expression by genetic imprinting
transcription, DNA-templated
regulation of transcription, DNA-templated
multicellular organism development
chromatin modification
histone H3-K4 demethylation
DNA methylation involved in gamete generation
regulation of DNA methylation
oxidation-reduction process
biological_process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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