Hamburger Menu Button
Thermo Fisher Scientific Logo
Sign in
Don't have an account ? Create Account
  • Products
    • Antibodies
    • Cell Culture Media
    • Chemicals
    • Chromatography Columns and Cartridges
    • Lab Equipment
    • Lab Plasticware and Supplies
    • Microplates
    • Oligos, Primers, Probes and Genes
    • TaqMan Real-Time PCR Assays
    • Greener Products
    • See all product categories
  • Applications
    • Bioprocessing
    • Cell Culture and Transfection
    • Cell and Gene Therapy
    • Chromatography
    • Molecular Testing
    • Digital Solutions
    • DNA and RNA Extraction and Analysis
    • Spectroscopy, Elemental and Isotope Analysis
    • See all applications and techniques
  • Services
    • 360° CDMO and CRO Solutions
    • CDMO Services
    • CRO Services
    • Custom Services
    • Enterprise Services
    • Financial and Leasing Services
    • Instrument Services
    • Lab Informatics
    • OEM and Commercial Supply
    • Training Services
    • Unity Lab Services
    • See all services
  • Help and Support
    • How to Order
    • Instrument Support
    • Learning Centers
    • Register for an Account
    • Technical Support Centers
    • See all help and support topics
  • Popular
    • TaqMan Real-Time PCR Assays
      TaqMan Real-Time PCR Assays
    • Antibodies
      Antibodies
    • Oligos, Primers & Probes
      Oligos, Primers & Probes
    • GeneArt Gene Synthesis
      GeneArt Gene Synthesis
    • Cell Culture Plastics
      Cell Culture Plastics
  • Contact Us
  • Quick Order
  • Order Status and Tracking
  • Documents and Certificates
Thermo Fisher Scientific Logo

Search Thermo Fisher Scientific

Search All
Search button Close
          • Order Status
          • Quick Order
          • Sign in
            Sign in
            Don't have an account ? Create Account
            • Account
            • Check Order Status
            • Aspire Member Program
            • Connect: Lab, Data, Apps
            • Custom Products & Projects
            • Services Central

          Disclaimer

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • JMJD1A Antibodies

          Proteintech

          KDM3A/JMJD1A Polyclonal Antibody

          54 References
          View all (16) JMJD1A antibodies

          Promotion

          View available promotion(s)

          Promo code: {{promo.promoCode}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

          Datasheet
          Protocols
          Questions & Answers
          Datasheet
          Protocols
          Questions & Answers

          Cite KDM3A/JMJD1A Polyclonal Antibody

          • Antibody Testing Data (10)
          KDM3A/JMJD1A Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.
          KDM3A/JMJD1A Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 10

          {{ $ctrl.currentElement.advancedVerification.fullName }}
          {{ $ctrl.currentElement.advancedVerification.text }}

          KDM3A/JMJD1A Antibody (12835-1-AP) in ICC/IF

          Immunofluorescent analysis of ( 4% PFA ) fixed HepG2 cells using 12835-1-AP (KDM3A,JMJD1A antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
          PMID: {{$ctrl.currentElement.benchSciPubmedId}}
          View Product

          {{$ctrl.videoDesc}}

          {{$ctrl.videoLongDesc}}

          KDM3A/JMJD1A Antibody in Immunocytochemistry (ICC/IF)
          KDM3A/JMJD1A Antibody in Immunocytochemistry (ICC/IF)
          KDM3A/JMJD1A Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          KDM3A/JMJD1A Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          KDM3A/JMJD1A Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          KDM3A/JMJD1A Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          KDM3A/JMJD1A Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          KDM3A/JMJD1A Antibody in Western Blot (WB)
          KDM3A/JMJD1A Antibody in Western Blot (WB)
          KDM3A/JMJD1A Antibody in Immunoprecipitation (IP)

          Product Details

          12835-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:1,000-1:4,000
          View 31 publications 31 publications

          Immunohistochemistry (IHC)

          -
          View 10 publications 10 publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:20-1:200
          -

          Immunocytochemistry (ICC/IF)

          1:50-1:500
          View 4 publications 4 publications

          Immunoprecipitation (IP)

          0.5-4.0 µg
          View 2 publications 2 publications

          ChIP assay (ChIP)

          Assay-dependent
          View 6 publications 6 publications

          Not applicable (N/A)

          -
          View 1 publication 1 publication
          Product Specifications

          Species Reactivity

          Human, Mouse

          Published species

          Human, Mouse

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          KDM3A,JMJD1A Fusion Protein Ag3581 (1-358 aa encoded by BC038297)
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.13 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Product Specific Information

          This antibody recognize the N-term of KDM3A (JMJD1A).

          Immunogen sequence: MVLTLGESW PVLVGRRFLS LSAADGSDGS HDSWDVERVA EWPWLSGTIR AVSHTDVTKK DLKVCVEFDG ESWRKRRWIE VYSLLRRAFL VEHNLVLAER KSPEISERIV QWPAITYKPL LDKAGLGSIT SVRFLGDQQR VFLSKDLLKP IQDVNSLRLS LTDNQIVSKE FQALIVKHLD ESHLLKGDKN LVGSEVKIYS LDPSTQWFSA TVVNGNPASK TLQVNCEEIP ALKIVDPSLI HVEVVHDNLV TCGNSARIGA VKRKSSENNG TLVSKQAKSC SEASPSMCPV QSVPTTVFKE ILLGCTAATP PSKDPRQQST PQAANSPPNL GAKIPQGCHK QSLPEEISSC LNTKSEALR (1-358 aa encoded by BC038297 )

          Target Information

          JMJD1A is a histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. It preferentially demethylates mono- and dimethylated H3 'Lys-9' residue, with a preference for dimethylated residue, while it has weak or no activity on trimethylated H3 'Lys-9'. Demethylation of Lys residue generates formaldehyde and succinate. JMJD1A is involved in hormone-dependent transcriptional activation, by participating in recruitment to androgen-receptor target genes, resulting in H3 'Lys-9' demethylation and transcriptional activation. It's also Involved in spermatogenesis by regulating expression of target genes such as PRM1 and TMP1 which are required for packaging and condensation of sperm chromatin. Involved in obesity resistance through regulation of metabolic genes such as PPARA and UCP1.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: [histone H3]-dimethyl-L-lysine(9) demethylase 3A; DKFZp686A24246; DKFZp686P07111; JmjC domain-containing histone demethylation protein 2A; jumonji C domain-containing histone demethylase 2A; Jumonji domain-containing protein 1A; lysine (K)-specific demethylase 3A; Lysine-specific demethylase 3A; testis specific gene A; testis-specific protein A

          View more View less

          Gene Aliases: 1700105C21Rik; C230043E16Rik; JHDM2A; JHMD2A; JMJD1; JMJD1A; KDM2A; KDM3A; KIAA0742; TGSA; TSGA

          View more View less

          UniProt ID: (Human) Q9Y4C1, (Mouse) Q6PCM1

          View more View less

          Entrez Gene ID: (Human) 55818, (Mouse) 104263

          View more View less

          Function(s)
          transcription regulatory region sequence-specific DNA binding core promoter binding transcription factor activity, sequence-specific DNA binding iron ion binding histone demethylase activity androgen receptor binding dioxygenase activity sulfonate dioxygenase activity protein binding oxidoreductase activity 2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity procollagen-proline dioxygenase activity hypophosphite dioxygenase activity DNA-N1-methyladenine dioxygenase activity metal ion binding C-19 gibberellin 2-beta-dioxygenase activity C-20 gibberellin 2-beta-dioxygenase activity
          Process(es)
          transcription, DNA-templated regulation of transcription, DNA-templated spermatogenesis spermatid nucleus elongation hormone-mediated signaling pathway positive regulation of gene expression chromatin modification cell differentiation androgen receptor signaling pathway histone H3-K9 demethylation histone H3-K9 dimethylation positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter formaldehyde biosynthetic process negative regulation of histone H3-K9 methylation oxidation-reduction process response to hypoxia male gonad development regulation of stem cell population maintenance regulation of stem cell differentiation
          It has to be done as per old AB suggested Products section.
          guarantee_icon

          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

          Learn more
          help_icon

          We're here to help

          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

          Contact tech support
          Ordering Plus Icon Minus Icon
          • Order Status
          • Order Help
          • Quick Order
          • Supply Center
          • eProcurement
          Support Plus Icon Minus Icon
          • Help and Support
          • Contact Us
          • Technical Support Centers
          • Documents and Certificates
          • Report a Site Issue
          Resources Plus Icon Minus Icon
          • Learning Centers
          • Promotions
          • Events and Webinars
          • Social Media
          About Thermo Fisher Plus Icon Minus Icon
          • About Us
          • Careers
          • Investors
          • News
          • Social Responsibility
          • Trademarks
          • Consumer Health Data Privacy Policy
          Our Portfolio Plus Icon Minus Icon
          • Thermo Scientific
          • Applied Biosystems
          • Invitrogen
          • Gibco
          • Ion Torrent
          • Fisher Scientific
          • Unity Lab Services
          • Patheon
          • PPD
          • Terms & Conditions
          • Privacy Information Center
          • Price & Freight Policy
          © 2006-2025 Thermo Fisher Scientific Inc. All rights reserved. All trademarks are the property of Thermo Fisher Scientific and its subsidiaries unless otherwise specified.
          United States flag icon
          United States

          Your items have has been added!


          Host server : magellan-search-67c77f6dc7-n6nf2:80/100.66.135.186:80.
          git-commit: 545e792480003146e539d624bd2a21b51d198228
          git-url: https://github.com/thermofisher/magellan-search
          git-branch: release/2.31.0-2025.06.23-1.0