Invitrogen

KGF Polyclonal Antibody

View all (12) KGF antibodies

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Datasheet
Protocols
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Datasheet
Protocols
Questions & Answers

Product Details

PA5-115465

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200
-

Immunocytochemistry (ICC/IF)

1:100-1:500
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human FGF7(Accession P21781), corresponding to amino acid residues L30-D80.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2900101

Product Specific Information

Antibody detects endogenous levels of total KGF.

Target Information

Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Required for normal branching morphogenesis. Growth factor active on keratinocytes. Possible major paracrine effector of normal epithelial cell proliferation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: FGF-7; Fibroblast growth factor 7; HBGF-7; Heparin-binding growth factor 7; Keratinocyte growth factor; KGF

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Gene Aliases: Fgf-7; FGF7; HBGF-7; KGF

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UniProt ID: (Human) P21781, (Rat) Q02195, (Mouse) P36363

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Entrez Gene ID: (Human) 2252, (Rat) 29348, (Mouse) 14178

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Function(s)
protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity type 2 fibroblast growth factor receptor binding protein binding growth factor activity heparin binding 1-phosphatidylinositol-3-kinase activity chemoattractant activity phosphatidylinositol-4,5-bisphosphate 3-kinase activity fibroblast growth factor receptor binding receptor binding
Process(es)
ovarian follicle development phosphatidylcholine biosynthetic process positive regulation of cell proliferation fibroblast growth factor receptor signaling pathway phospholipid biosynthetic process mesenchymal cell proliferation positive regulation of keratinocyte proliferation lung development hair follicle morphogenesis actin cytoskeleton reorganization protein localization to cell surface wound healing surfactant homeostasis positive regulation of epithelial cell proliferation positive regulation of peptidyl-tyrosine phosphorylation positive chemotaxis positive regulation of keratinocyte migration positive regulation of cell division branching involved in salivary gland morphogenesis positive regulation of epithelial cell proliferation involved in lung morphogenesis regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling secretion by lung epithelial cell involved in lung growth positive regulation of defense response to virus by host MAPK cascade signal transduction epidermis development response to wounding regulation of phosphatidylinositol 3-kinase signaling peptidyl-tyrosine phosphorylation phosphatidylinositol-3-phosphate biosynthetic process positive regulation of GTPase activity positive regulation of transcription, DNA-templated phosphatidylinositol phosphorylation phosphatidylinositol-mediated signaling xenophagy
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