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Invitrogen
KHDRBS3 Polyclonal Antibody
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FIGURE: 1 / 3
KHDRBS3 Antibody (PA5-41821) in ICC/IF
Immunofluorescence analysis of KHDRBS3 in human fibroblasts. Cells were fixed with 2% PFA in PBS and permeabilized with 0.1% Triton X-100 in PBS. Cells were blocked with 3% Donkey serum in PBS followed by staining with a KHDRBS3 polyclonal antibody (Product # PA5-41821) at a dilution of 1:200. Cells washed extensively followed by an incubation with anti-rabbit Alexa Fluor 594 (Product # A-21207) at a dilution of 1:500 (red). Data courtesy of Antibody Data Exchange Program.
Product Details
PA5-41821
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide directed towards the C-terminal of human KHDRBS3 (aa 281-330).
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2610045
Product Specific Information
Peptide sequence: EQSYDSYDNS YSTPAQSGAD YYDYGHGLSE ETYDSYGQEE WTNSRHKAPS
Sequence homology: Cow: 100%; Dog: 86%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 86%; Rabbit: 100%; Rat: 100%
Target Information
As a RNA-binding protein, KHDRBS3 plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. KHDRBS3 may play a role as a negative regulator of cell growth. It inhibits cell proliferation and involved in splice site selection of vascular endothelial growth factor. It induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. RNA-binding abilities are down-regulated by tyrosine kinase PTK6. It also involved in post-transcriptional regulation of HIV-1 gene expression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: KH domain containing, RNA binding, signal transduction associated 3; KH domain-containing, RNA-binding, signal transduction-associated protein 3; RNA-binding protein T-Star; Sam68-like mammalian protein 2; Sam68-like phosphotyrosine protein; Sam68-like phosphotyrosine protein, T-STAR; SLM-2
Gene Aliases: Etle; etoile; KHDRBS3; SALP; SLM-2; SLM2; T-STAR; TSTAR
UniProt ID: (Human) O75525
Entrez Gene ID: (Human) 10656
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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