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Invitrogen
KHDRBS3 Polyclonal Antibody
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FIGURE: 1 / 2
KHDRBS3 Antibody (PA5-85471) in ICC/IF
KHDRBS3 Polyclonal Antibody detects KHDRBS3 protein at nucleus by immunofluorescent analysis. Sample: HeLa cells were fixed in 4% paraformaldehyde/PBS for 15 min. Green: KHDRBS3 protein stained by KHDRBS3 Polyclonal Antibody (Product # PA5-85471) diluted at 1:500. Blue: Hoechst 33342 staining.
Product Details
PA5-85471
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human KHDRBS3. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.83 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2792611
Product Specific Information
Keep as concentrated solution.
Predicted reactivity: Mouse (98%), Rat (97%), Bovine (100%).
Positive Control: SK-N-SH, SK-N-AS.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
As a RNA-binding protein, KHDRBS3 plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. KHDRBS3 may play a role as a negative regulator of cell growth. It inhibits cell proliferation and involved in splice site selection of vascular endothelial growth factor. It induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. RNA-binding abilities are down-regulated by tyrosine kinase PTK6. It also involved in post-transcriptional regulation of HIV-1 gene expression.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: KH domain containing, RNA binding, signal transduction associated 3; KH domain-containing, RNA-binding, signal transduction-associated protein 3; RNA-binding protein T-Star; Sam68-like mammalian protein 2; Sam68-like phosphotyrosine protein; Sam68-like phosphotyrosine protein, T-STAR; SLM-2
Gene Aliases: Etle; etoile; KHDRBS3; SALP; SLM-2; SLM2; T-STAR; TSTAR
UniProt ID: (Human) O75525
Entrez Gene ID: (Human) 10656
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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