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Recommended positive controls: 293T, A431, Jurkat, Raji.
Predicted reactivity: Mouse (88%), Rat (87%), Bovine (90%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Inhibits the poly(ADP-ribosyl)ation activity of PARP1 and the degradation of PARP1 by CASP3 following genotoxic stress. Binds to double-stranded RNA or DNA without sequence specificity. Involved in development of the eye and of primordial germ cells.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: HBV X-transactivated gene 5 protein; HBV XAg-transactivated protein 5; HLA-HA8; Minor histocompatibility antigen HA-8; penguin homolog; protein 5 transactivated by hepatitis B virus X antigen (HBxAg); Pumilio homolog 3; pumilio RNA-binding family member 3
Gene Aliases: cPERP-C; HA-8; HLA-HA8; KIAA0020; PEN; PUF-A; PUF6; PUM3; XTP5
UniProt ID: (Human) Q15397
Entrez Gene ID: (Human) 9933
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