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KIAA1530 Antibody (MA5-27844) in ICC/IF
Immunocytochemistry-Immunofluorescence analysis of KIAA1530 was performed in HeLa cells fixed in 4% paraformaldehyde at RT for 15 min. Green: KIAA1530 Monoclonal Antibody (GT816) (Product # MA5-27844) diluted at 1:500. Red: alpha Tubulin 4a, a cytoskeleton marker. Blue: Hoechst 33342 staining. Scale bar = 10 µm.
Product Details
MA5-27844
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
GT816
Immunogen
Recombinant protein encompassing a sequence within the N-terminus region of human UVSSA. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein G
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2735253
Product Specific Information
Positive Control: HeLa, A375
Predicted Reactivity: Mouse (83%), Rat (83%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The protein encoded by KIAA1530 appears to be involved in ubiquitination and dephosphorylation of RNA polymerase II subunits that stall after UV irradiation. The encoded protein interacts with several members of the nucleotide excision repair complex, and is thought to be involved in the transcription-coupled nucleotide excision repair (TC-NER) pathway to help remove lesions in the DNA that block transcription. Defects in KIAA1530 can cause UV-sensitive syndrome 3. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: UV-stimulated scaffold protein A
Gene Aliases: KIAA1530; UVSS3; UVSSA
UniProt ID: (Human) Q2YD98
Entrez Gene ID: (Human) 57654
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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