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Invitrogen
KIDINS220 Polyclonal Antibody
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KIDINS220 Antibody (PA5-22116) in IHC (P)
KIDINS220 Polyclonal Antibody detects KIDINS220 protein at membrane on mouse esophagus by immunohistochemical analysis. Sample: Paraffin-embedded mouse esophagus. KIDINS220 Polyclonal Antibody (Product # PA5-22116) dilution: 1:500. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min.
Product Details
PA5-22116
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide encompassing a sequence within the Intracellular domain of human KIDINS220. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_11156995
Product Specific Information
Recommended positive controls: 293T, H1299, HeLaS3, HepG2, Molt-4, Raji.
Predicted reactivity: Rat (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes a transmembrane protein that is preferentially expressed in the nervous system where it controls neuronal cell survival, differentiation into exons and dendrites, and synaptic plasticity. The encoded protein interacts with membrane receptors, cytosolic signaling components, and cytoskeletal proteins, serving as a scaffold that mediates crosstalk between the neurotrophin pathway and several other intracellular signaling pathways. Aberrant expression of this gene is associated with the onset of various neuropsychiatric disorders and neurodegenerative diseases, including Alzheimer's disease. Naturally occurring mutations in this gene are associated with a syndrome characterized by spastic paraplegia, intellectual disability, nystagmus and obesity. Alternative splicing results in multiple transcript variants.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ankyrin repeat-rich membrane spanning; Ankyrin repeat-rich membrane-spanning protein; Kinase D-interacting substrate of 220 kDa; kinase D-interacting substrate, 220kDa; MGC163482; truncated KIDINS220
Gene Aliases: 3110039L19Rik; AI194387; AI316525; ARMS; C330002I19Rik; KIAA1250; KIDINS220; mKIAA1250
UniProt ID: (Human) Q9ULH0
Entrez Gene ID: (Human) 57498, (Mouse) 77480
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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