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Invitrogen
KIDINS220 Monoclonal Antibody (P220 1F8/3)
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KIDINS220 Antibody (MA1-90667) in WB, IP
Medical sciences (Basel, Switzerland) 2022 -
Western blot analysis of TRPV1/ARMS/AKAP79 in TRPV1/ARMS transfected and PKA stimulated HEK293 via anti-TRPV1, anti-ARMS, and anti-AKAP79. BANDS at ~79 kDa: AKAP79, BANDS at ~120 kDa: TRPV1, BANDS at ~220 kDa: ARMS.
Product Details
MA1-90667
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Rat
Published species
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
P220 1F8/3
Immunogen
Recombinant Kidins220/ARMS (last 347 amino acids at the carboxy terminus) protein.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
IgG fraction
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2130952
Product Specific Information
MA1-90667 detects Kidins220 from rat samples.
Target Information
This gene encodes a transmembrane protein that is preferentially expressed in the nervous system where it controls neuronal cell survival, differentiation into exons and dendrites, and synaptic plasticity. The encoded protein interacts with membrane receptors, cytosolic signaling components, and cytoskeletal proteins, serving as a scaffold that mediates crosstalk between the neurotrophin pathway and several other intracellular signaling pathways. Aberrant expression of this gene is associated with the onset of various neuropsychiatric disorders and neurodegenerative diseases, including Alzheimer's disease. Naturally occurring mutations in this gene are associated with a syndrome characterized by spastic paraplegia, intellectual disability, nystagmus and obesity. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: ankyrin repeat-rich membrane spanning protein; Ankyrin repeat-rich membrane-spanning protein; kinase D-interacting substance 220; kinase D-interacting substance of 220 kDa; Kinase D-interacting substrate of 220 kDa; MGC163482
Gene Aliases: ARMS; Kidins220
UniProt ID: (Rat) Q9EQG6
Entrez Gene ID: (Rat) 116478
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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