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Immunogen sequence: SAQCLPETLS TLRYASRAQR VTTRPQAPKS PVAKQPQRLE TEMLQLQEEN RRLQFQLDQM DCKASGLSGA RVAWAQRNLY GML
Highest antigen sequence identity to the following orthologs: Mouse - 77%, Rat - 78%.
KIF12 encodes a member of the kinesin superfamily of microtubule-associated molecular motors with functions related to the microtubule cytosekelton. Members of this superfamily play important roles in intracellular transport and cell division. A similar protein in mouse functions in the beta cell antioxidant signaling cascade, acting as a scaffold for the transcription factor specificity protein 1 (Sp1). Mice that lack this gene exhibit beta cell oxidative stress resulting in hypoinsulinemic glucose intolerance.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Kinesin-like protein KIF12; RP1156P10.3
Gene Aliases: KIF12
UniProt ID: (Human) Q96FN5
Entrez Gene ID: (Human) 113220
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