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Positive Control: U87-MG, SK-N-SH, SK-N-AS
Predicted Reactivity: Mouse (85%), Rat (86%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
KIF12 encodes a member of the kinesin superfamily of microtubule-associated molecular motors with functions related to the microtubule cytosekelton. Members of this superfamily play important roles in intracellular transport and cell division. A similar protein in mouse functions in the beta cell antioxidant signaling cascade, acting as a scaffold for the transcription factor specificity protein 1 (Sp1). Mice that lack this gene exhibit beta cell oxidative stress resulting in hypoinsulinemic glucose intolerance.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Kinesin-like protein KIF12; RP1156P10.3
Gene Aliases: KIF12
UniProt ID: (Human) Q96FN5
Entrez Gene ID: (Human) 113220
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