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Abnova
KIF1B Polyclonal Antibody, MaxPab™
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Product Details
H00023095-B01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KIF1B (AAH01415, 1 a.a. approximately 579 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
0.5-1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MSKTSLGQSM SKYDLLVWFE ISELEPTGEY IPAVVDHTAG LPCQGTFLLH QGIQRRITVT IIHEKGSELH WKDVRELVVG RIRNKPEVDE AAVDAILSLN IISAKYLKSS HNSSRTFYRF EAVWDSSLHN SLLLNRVTPY GEKIYMTLSA YLELDHCIQP AVITKDVCMV FYSRDAKISP PRSLRSLFGS GYSKSPDSNR VTGIYELSLC KMSDTGSPGM QRRRRKILDT SVAYVRGEEN LAGWRPRGDS LILEHQWELE KLELLHEVEK TRHFLLLRER LGDSIPKSLS DSLSPSLSSG TLSTSTSISS QISTTTFESA ITPSESSGYD SGDIESLVDR EKELATKCLQ LLTHTFNREF SQVHGSVSDC KLSDISPIGR DPSESSFSSA TLTPSSTCPS LVDSRSNSLD QKTPEANSRA SSPCPEFEQF QIVPAVETPY LARAGKNEFL NLVPDIEEIR PSSVVSKKGY LHFKEPLYSN WAKHFVVVRR PYVFIYNSDK DPVERGIINL STAQVEYSED QQAMVKTPNT FAVCTKHRGV LLQALNDKDM NDWLYAFNPL LAGTIRSKLS RRCPSQSKY
Target Information
The kinesins constitute a large family of microtubule-dependent motor proteins, which are responsible for the distribution of numerous organelles, vesicles and macromolecular complexes throughout the cell. Individual kinesin members play crucial roles in cell division, intracellular transport and membrane trafficking events including endocytosis and transcytosis. KIF1B is a member of the KIF1/Unc104 family of kinesin-like proteins that are involved in the transport of mitochondria or synaptic vesicles in axons. KIF1B is an amino-terminal-type motor protein that is ubiquitously expressed, with the most abundant levels in differentiated nerve cells. The human KIF1B gene maps to chromosome 1p36. 2. Defects in axonal transport due to mutations at the KIF1B gene can underlie the human peripheral neuropathy phenotype. The mouse KIF1B gene generates an alternatively spliced transcript, which produces two isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: kinesin superfamily protein KIF1B; Kinesin-like protein KIF1B; Klp
Gene Aliases: CMT2; CMT2A; CMT2A1; HMSNII; KIAA0591; KIAA1448; KIF1B; KLP; NBLST1
UniProt ID: (Human) O60333
Entrez Gene ID: (Human) 23095
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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