Proteintech

KIF20A Polyclonal Antibody

KIF20A Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 6

KIF20A Antibody (15911-1-AP) in IHC (P)

Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using (Product # 15911-1-AP) (KIF20A antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

KIF20A Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

15911-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 4 publications 4 publications

Immunohistochemistry (IHC)

View 2 publications 2 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200

Immunocytochemistry (ICC/IF)

Assay-dependent

View 2 publications 2 publications

Immunoprecipitation (IP)

0.5-4.0 µg

Not applicable (N/A)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KIF20A Fusion Protein Ag8700 (1-351 aa encoded by BC012999)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.19 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MSQGILSPP AGLLSDDDVV VSPMFESTAA DLGSVVRKNL LSDCSVVSTS LEDKQQVPSE DSMEKVKVYL RVRPLLPSEL ERQEDQGCVR IENVETLVLQ APKDSFALKS NERGIGQATH RFTFSQIFGP EVGQASFFNL TVKEMVKDVL KGQNWLIYTY GVTNSGKTHT IQGTIKDGGI LPRSLALIFN SLQGQLHPTP DLKPLLSNEV IWLDSKQIRQ EEMKKLSLLN GGLQEEELST SLKRSVYIES RIGTSTSFDS GIAGLSSISQ CTSSSQLDET SHRWAQPDTA PLPVPANIRF SIWISFFEIY NELLYDLLEP PSQQRKRQTL RLCEDQNGNP YVKDLNWIHV QD (1-351 aa encoded by BC012999)

Target Information

Mitotic kinesin required for chromosome passenger complex (CPC)-mediated cytokinesis. Following phosphorylation by PLK1, involved in recruitment of PLK1 to the central spindle. Interacts with guanosine triphosphate (GTP)-bound forms of RAB6A and RAB6B. May act as a motor required for the retrograde RAB6 regulated transport of Golgi membranes and associated vesicles along microtubules. Has a microtubule plus end-directed motility. [UniProt]

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Identification of prognostic and therapeutic biomarkers in type 2 papillary renal cell carcinoma.

World journal of surgical oncology

Wang Y,Tian X,Zhu SX,Xu WH,Anwaier A,Su JQ,Gan HL,Qu YY,Zhao JY,Zhang HL,Ye DW

Thu Mar 16 00:00:00 UTC 2023

Mir-153-3p Modulates the Breast Cancer Cells' Chemosensitivity to Doxorubicin by Targeting KIF20A.

Cancers

Rahman KU,Yang S,Azam N,Yuan Z,Yu J,Zhao C,Feng B

Sat Mar 11 00:00:00 UTC 2023

The mechanism of acentrosomal spindle assembly in human oocytes.

Science (New York, N.Y.)

Wu T,Dong J,Fu J,Kuang Y,Chen B,Gu H,Luo Y,Gu R,Zhang M,Li W,Dong X,Sun X,Sang Q,Wang L

Fri Nov 18 00:00:00 UTC 2022

Five-gene signature associating with Gleason score serve as novel biomarkers for identifying early recurring events and contributing to early diagnosis for Prostate Adenocarcinoma.

Journal of Cancer

Zhang L,Li Y,Wang X,Ping Y,Wang D,Cao Y,Dai Y,Liu W,Tao Z

Sat Nov 11 00:00:00 UTC 2023

KIF20A Predicts Poor Survival of Patients and Promotes Colorectal Cancer Tumor Progression through the JAK/STAT3 Signaling Pathway.

Disease markers

Zhang Q,Di J,Ji Z,Mi A,Li Q,Du X,Wang A,Wang A,Qin C

Thu Jun 03 00:00:00 UTC 2021

Bisphenol A triggers the malignancy of acute myeloid leukemia cells via regulation of IL-4 and IL-6.

Journal of biochemical and molecular toxicology

Zhang S,Li J,Fan J,Wu X

Wed Jan 01 00:00:00 UTC 2020

Coupling fission and exit of RAB6 vesicles at Golgi hotspots through kinesin-myosin interactions.

Nature communications

Miserey-Lenkei S,Bousquet H,Pylypenko O,Bardin S,Dimitrov A,Bressanelli G,Bonifay R,Fraisier V,Guillou C,Bougeret C,Houdusse A,Echard A,Goud B

Wed Nov 01 00:00:00 UTC 2017

Coupling fission and exit of RAB6 vesicles at Golgi hotspots through kinesin-myosin interactions.

Nature communications

Miserey-Lenkei S,Bousquet H,Pylypenko O,Bardin S,Dimitrov A,Bressanelli G,Bonifay R,Fraisier V,Guillou C,Bougeret C,Houdusse A,Echard A,Goud B

Wed Nov 01 00:00:00 UTC 2017

Coupling fission and exit of RAB6 vesicles at Golgi hotspots through kinesin-myosin interactions.

Nature communications

Miserey-Lenkei S,Bousquet H,Pylypenko O,Bardin S,Dimitrov A,Bressanelli G,Bonifay R,Fraisier V,Guillou C,Bougeret C,Houdusse A,Echard A,Goud B

Wed Nov 01 00:00:00 UTC 2017

Coupling fission and exit of RAB6 vesicles at Golgi hotspots through kinesin-myosin interactions.

Nature communications

Miserey-Lenkei S,Bousquet H,Pylypenko O,Bardin S,Dimitrov A,Bressanelli G,Bonifay R,Fraisier V,Guillou C,Bougeret C,Houdusse A,Echard A,Goud B

Wed Nov 01 00:00:00 UTC 2017

Genistein-induced mitotic arrest of gastric cancer cells by downregulating KIF20A, a proteomics study.

Proteomics

Yan GR,Zou FY,Dang BL,Zhang Y,Yu G,Liu X,He QY

Wed Aug 01 00:00:00 UTC 2012

Genistein-induced mitotic arrest of gastric cancer cells by downregulating KIF20A, a proteomics study.

Proteomics

Yan GR,Zou FY,Dang BL,Zhang Y,Yu G,Liu X,He QY

Wed Aug 01 00:00:00 UTC 2012

Bioinformatics

Protein Aliases: GG10_2; Kinesin-like protein KIF20A; Mitotic kinesin-like protein 2; MKlp2; RAB6 interacting, kinesin-like (rabkinesin6); Rab6-interacting kinesin-like protein; Rabkinesin-6

View more View less

Gene Aliases: KIF20A; MKLP2; RAB6KIFL

View more View less

UniProt ID: (Human) O95235

View more View less

Entrez Gene ID: (Human) 10112

View more View less

Function(s)

microtubule motor activity transporter activity protein binding ATP binding microtubule binding ATPase activity protein kinase binding

Process(es)

mitotic cytokinesis cytokinesis cell separation after cytokinesis microtubule bundle formation microtubule-based movement protein transport vesicle-mediated transport

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more

KIF20A Polyclonal Antibody

KIF20A Antibody (15911-1-AP) in IHC (P)

Product Details

15911-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Not applicable (N/A)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

We're here to help

Your items have has been added!