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Invitrogen
KIF23 Polyclonal Antibody
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FIGURE: 1 / 4
KIF23 Antibody (PA5-100863) in ICC/IF
Immunocytochemistry analysis of KIF23 in A549 cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with KIF23 polyclonal antibody (Product # PA5-100863) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG(H+L) (Red) and an AlexaFluor488 conjugated goat anti-mouse IgG(H+L) (Green) were used as the secondary antibodies. The nuclear counter stain is DAPI (blue).
Product Details
PA5-100863
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human KIF23(Accession Q02241), corresponding to amino acid residues V432-S482.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2850361
Product Specific Information
Antibody detects endogenous levels of total KIF23.
Target Information
The protein encoded by this gene is a member of kinesin-like protein family. This family includes microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. This protein has been shown to cross-bridge antiparallel microtubules and drive microtubule movement in vitro. Alternate splicing of this gene results in two transcript variants encoding two different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: kinesin-like 5 (mitotic kinesin-like protein 1); Kinesin-like protein 5; Kinesin-like protein KIF23; Mitotic kinesin-like protein 1
Gene Aliases: 3110001D19Rik; C87313; CHO1; KIF23; KNSL5; MKLP-1; MKLP1
UniProt ID: (Human) Q02241, (Mouse) E9Q5G3
Entrez Gene ID: (Human) 9493, (Mouse) 71819
mitotic cytokinesis
cytokinesis
microtubule-based movement
cell cycle
mitotic nuclear division
positive regulation of cytokinesis
mitotic spindle midzone assembly
cell division
mitotic spindle elongation
actomyosin contractile ring assembly
retrograde vesicle-mediated transport, Golgi to ER
antigen processing and presentation of exogenous peptide antigen via MHC class II
plus-end-directed vesicle transport along microtubule
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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