Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: IEEQVRRGLEG KEQEVPTFTE LSRENDEEKV TFNLSKGACS SSGATSSKSS TLGPSALKTI GSSASVKRKE SS
Highest antigen sequence identity to the following orthologs - mouse 82%, rat 85%.
Kin is a nuclear protein that forms intranuclear foci during proliferation and is redistributed in the nucleoplasm during the cell cycle. Short-wave ultraviolet light provokes the relocalization of the protein, suggesting its participation in the cellular response to DNA damage. Originally selected based on protein-binding with RecA antibodies, the mouse protein presents a limited similarity with a functional domain of the bacterial RecA protein, a characteristic shared by the human ortholog.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Binding to curved DNA; DNA/RNA-binding protein KIN17; KIN, antigenic determinant of recA protein homolog
Gene Aliases: BTCD; KIN; KIN17; Rts2
UniProt ID: (Human) O60870
Entrez Gene ID: (Human) 22944
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