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Abnova
KIRREL2 Monoclonal Antibody (2B9-1D3)
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Product Details
H00084063-M01
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
2B9-1D3
Immunogen
KIRREL2 (AAH07312, 1 a.a. approximately 219 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: MLRMRVPALL VLLFCFRGRA GPSPHLLQQP EDLVVLLGEG GAQASLGRRA SASFSEQKNL MRIPGSSDGS SSRGPEEEET GSREDRGPIV HTDHSDLVLE EEGTLETKDP TNGYYKVRGV SVSLSLGEAP GGGLFLPPPS PLGPPGTPTF YDFNPHLGMV PPCRLYRARA GYLTTPHPRA FTSYIKPTSF GPPDLAPGTP PFPYAAFPTP SHPRLQTHV
Target Information
This gene encodes a type I transmembrane protein and member of the immunoglobulin superfamily of cell adhesion molecules. The encoded protein localizes to adherens junctions in pancreatic beta cells and regulates insulin secretion. Autoantibodies against the encoded protein have been detected in serum from patients with type 1 diabetes. This gene may also play a role in glomerular development and decreased expression of this gene has been observed in human glomerular diseases. This gene and the related opposite-strand gene nephrin are regulated by a bidirectional promoter.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DKFZp564A1164; Kin of IRRE-like protein 2; Kin of irregular chiasm-like protein 2; MGC15718; nephrin-like 3; nephrin-like gene 1; Nephrin-like protein 3
Gene Aliases: FILTRIN; KIRREL2; NEPH3; NLG1; UNQ5827/PRO19646
UniProt ID: (Human) Q6UWL6
Entrez Gene ID: (Human) 84063
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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