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Invitrogen
KLC3 Polyclonal Antibody
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FIGURE: 1 / 4
KLC3 Antibody (PA5-100592) in ICC/IF
Immunocytochemistry analysis of KLC3 in HepG2 cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with KLC3 polyclonal antibody (Product # PA5-100592) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG(H+L) (Red) and an AlexaFluor488 conjugated goat anti-mouse IgG(H+L) (Green) were used as the secondary antibodies. The nuclear counter stain is DAPI (blue).
Product Details
PA5-100592
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human KLC3(Accession Q6P597), corresponding to amino acid residues H146-A196.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2850099
Product Specific Information
Antibody detects endogenous levels of total KLC2.
Target Information
KLC3 encodes a member of the kinesin light chain gene family. Kinesins are molecular motors involved in the transport of cargo along microtubules, and are composed of two kinesin heavy chain (KHC) and two kinesin light chain (KLC) molecules. KLCs are thought to typically be involved in binding cargo and regulating kinesin activity. In the rat, a protein similar to this gene product is expressed in post-meiotic spermatids, where it associates with structural components of sperm tails and mitochondria.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: kinesin light chain 2; Kinesin light chain 3; Kinesin light chain KLCt; KLC2-like
Gene Aliases: BC017147; KLC2; KLC2L; KLC3; KLCt; KNS2B
UniProt ID: (Human) Q6P597, (Mouse) Q91W40, (Rat) Q68G30
Entrez Gene ID: (Human) 147700, (Mouse) 232943, (Rat) 171549
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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