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          • Primary Antibodies ›
          • KLF2/3/4/6/7/8/12 Antibodies

          Osenses

          KLF 2-4, 6-8, 12 Polyclonal Antibody

          2 References

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          Datasheet
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          Datasheet
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          Cite KLF 2-4, 6-8, 12 Polyclonal Antibody

          Product Details

          OSK00052W-100UL

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:300-1:2,000
          -

          Immunohistochemistry (IHC)

          1:300-1:2,000
          -

          Miscellaneous PubMed (MISC)

          -
          View 2 publications 2 publications
          Product Specifications

          Species Reactivity

          Mouse, Rat, Human

          Host/Isotype

          Rabbit / Ig

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          A synthetic from the c-terminal of human Krueppel-like factor 2, 3, 4, 6, 7, 8, 12 (KLF2, KLF3, KLF4, KLF6, KLF7, KLF8, KLF12) conjugated to an immunogenic carrier protein was used as the antigen
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Lyophilized

          Concentration

          Conc. Not Determined

          Storage buffer

          whole serum

          Contains

          no preservative

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Product Specific Information

          Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.

          The peptide is homologous in many species including rat, mouse.

          Specificity of this antibody: Krueppel-like factor 2, 3, 4, 6, 7, 8, 12.

          Target Information

          The Kruppel family of transcription factors (KLFs) are a set of C2H2-type zinc-finger DNA binding proteins that regulate gene expression.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: AP-2 repressor; AP-2rep transcription factor; B-cell-derived protein 1; Basic krueppel-like factor; Basic krueppel-like factor 3; basic kruppel like factor; Basic Kruppel- like factor; basic Kruppel-like factor; basic kruppel-like factor 3; CACCC-box-binding protein BKLF; core promoter element binding protein; Core promoter element-binding protein; endothelial Kruppel-like zinc finger protein; Epithelial zinc finger protein EZF; GC-rich binding factor; GC-rich sites-binding factor GBF; gut Kruppel-like factor; Gut-enriched krueppel-like factor; immediate early response, erythropoietin 1; KLF12 zinc finger transcriptional repressor; Krueppel-like factor 12; Krueppel-like factor 2; Krueppel-like factor 3; Krueppel-like factor 4; Krueppel-like factor 6; Krueppel-like factor 7; Krueppel-like factor 8; Kruppel-like factor 12; Kruppel-like factor 2 (lung); Kruppel-like factor 3 (basic); Kruppel-like factor 4 (Gut enriched kruppel-like factor) (Epithelial zinc-finger protein EZF); Kruppel-like factor 4 (gut); Kruppel-like factor 6; Kruppel-like factor 7 (ubiquitous); Kruppel-like factor 8; Kruppel-like factor 8, pseudogene 1; Kruppel-like factor LKLF; Kruppel-like zinc finger protein Zf9; Lung krueppel-like factor; lung Kruppel-like factor; lung Kruppel-like zinc finger transcription factor; Proto-oncogene BCD1; protooncogene B-cell derived 1; suppression of tumorigenicity 12 (prostate); Suppressor of tumorigenicity 12 protein; TEF-2; transcript ch138; Transcription factor Zf9; Transcriptional repressor AP-2rep; Ubiquitous krueppel-like factor; ubiquitous Kruppel-like factor; ubiquitous Kruppel-like transcription factor; Zinc finger protein 741

          View more View less

          Gene Aliases: 2700063E05Rik; 9830124P08Rik; 9930027G08Rik; A830097P10Rik; Aa1017; AI225908; AI315654; AI448727; AL024007; AP-2rep; AP2REP; B130052C06Rik; BCD1; BKLF; BKLF3; C86813; CBA1; COPEB; CPBP; D530033K05Rik; EZF; FM2; FM6; GBF; GKLF; HSPC122; Ierepo1; Ierepo3; KLF12; KLF2; KLF3; KLF4; KLF6; KLF7; KLF8; Klf8-ps1; LKLF; PAC1; R75280; RGD1565831; ST12; Tef-2; UKLF; ZF9; Zie; ZNF74; ZNF741

          View more View less

          UniProt ID: (Human) Q9Y4X4, (Human) Q9Y5W3, (Human) P57682, (Human) O43474, (Human) Q99612, (Human) O75840, (Human) O95600, (Mouse) O35738, (Mouse) Q60843, (Rat) Q9ET58, (Mouse) Q60980, (Mouse) Q60793, (Mouse) Q99JB0, (Mouse) Q8BLM0

          View more View less

          Entrez Gene ID: (Human) 11278, (Human) 10365, (Human) 51274, (Human) 9314, (Human) 1316, (Human) 8609, (Human) 11279, (Mouse) 16597, (Rat) 306110, (Mouse) 16598, (Rat) 306330, (Mouse) 16599, (Rat) 114845, (Mouse) 16600, (Rat) 114505, (Mouse) 23849, (Rat) 58954, (Mouse) 93691, (Rat) 363243, (Mouse) 245671, (Rat) 302582

          View more View less

          Function(s)
          RNA polymerase II regulatory region sequence-specific DNA binding transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding DNA binding transcription factor activity, sequence-specific DNA binding transcription corepressor activity protein binding metal ion binding sequence-specific DNA binding core promoter proximal region sequence-specific DNA binding transcription factor activity, sequence-specific DNA binding transcription factor recruiting core promoter binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding RNA polymerase II transcription factor binding transcriptional activator activity, RNA polymerase II transcription factor binding transcription cofactor binding beta-catenin binding zinc ion binding phosphatidylinositol 3-kinase regulator activity histone deacetylase binding transcription regulatory region DNA binding double-stranded DNA binding transcription coactivator activity nucleic acid binding transcription factor binding
          Process(es)
          transcription, DNA-templated B cell differentiation wound healing positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter cellular response to hydrogen peroxide cellular response to cycloheximide cellular response to peptide negative regulation of transcription from RNA polymerase II promoter regulation of transcription, DNA-templated regulation of transcription from RNA polymerase II promoter transcription from RNA polymerase II promoter negative regulation of cell proliferation epidermal cell differentiation response to organic substance negative regulation of phosphatidylinositol 3-kinase signaling negative regulation of muscle hyperplasia stem cell population maintenance cell differentiation post-embryonic camera-type eye development negative regulation of NF-kappaB transcription factor activity positive regulation of cellular protein metabolic process response to retinoic acid negative regulation of heterotypic cell-cell adhesion post-embryonic hemopoiesis regulation of cell proliferation negative regulation of cysteine-type endopeptidase activity involved in apoptotic process regulation of phosphatidylinositol 3-kinase activity negative regulation of interleukin-8 biosynthetic process positive regulation of nitric oxide biosynthetic process fat cell differentiation regulation of cell differentiation negative regulation of transcription, DNA-templated positive regulation of hemoglobin biosynthetic process negative regulation of smooth muscle cell proliferation epidermis morphogenesis positive regulation of protein metabolic process negative regulation of protein kinase B signaling positive regulation of telomerase activity canonical Wnt signaling pathway negative regulation of response to cytokine stimulus negative regulation of ERK1 and ERK2 cascade cellular response to growth factor stimulus cellular response to laminar fluid shear stress negative regulation of cell migration involved in sprouting angiogenesis negative regulation of chemokine (C-X-C motif) ligand 2 production cell morphogenesis in utero embryonic development negative regulation of interleukin-6 production erythrocyte homeostasis multicellular organism growth positive regulation of transcription from RNA polymerase II promoter in response to stress regulation of gene expression, epigenetic erythrocyte maturation Type I pneumocyte differentiation multicellular organism development cytokine-mediated signaling pathway response to laminar fluid shear stress cellular response to interleukin-1 cellular response to tumor necrosis factor cellular response to organic cyclic compound axonogenesis axon guidance dendrite morphogenesis cellular response to retinoic acid mesodermal cell fate determination positive regulation of gene expression negative regulation of gene expression somatic stem cell population maintenance regulation of axon regeneration negative regulation of inflammatory response negative regulation of leukocyte adhesion to arterial endothelial cell positive regulation of transcription regulatory region DNA binding
          It has to be done as per old AB suggested Products section.
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