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Product Details
61100ACTMOTIF
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
This kLF5 antibody was raised against a peptide derived from the N-terminus of mouse kLF5 (krueppel-like factor 5).
Conjugate
Form
Liquid
Purification
Antigen affinity chromatography
Storage buffer
70mM tris, pH 8, with 0.07mM EDTA, 105mM NaCl, 31mM glycine, 30% glycerol
Contains
0.035% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Target Information
KLF5 is a member of the Kruppel-like factor subfamily of zinc finger proteins. It contains three C2H2-type zinc fingers at the carboxyl-terminus that preferentially bind to cis-DNA elements that are GC rich. KLF5 is a transcription activator that promotes cell proliferation and oncogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: (intestinal Kruppel-like factor; basic transcription element binding protein 2; Basic transcription element-binding protein 2; BTE-binding protein 2; Colon krueppel-like factor; colon kruppel-like factor; GC box binding protein 2; GC-box-binding protein 2; Intestinal-enriched krueppel-like factor; intestinal-enriched kruppel-like factor; Klf5C isoform; Krueppel-like factor 5; Kruppel-like factor 5 (intestinal); RP11-505F3.5; Transcription factor BTEB2
Gene Aliases: 4930520J07Rik; BTEB2; CKLF; IKLF; KLF5
UniProt ID: (Human) Q13887, (Mouse) Q9Z0Z7
Entrez Gene ID: (Human) 688, (Mouse) 12224
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
protein binding
metal ion binding
nucleic acid binding
DNA binding
transcription factor activity, sequence-specific DNA binding
transcription factor binding
sequence-specific DNA binding
negative regulation of transcription from RNA polymerase II promoter
angiogenesis
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
microvillus assembly
regulation of microvillus assembly
skeletal muscle cell differentiation
positive regulation of fat cell differentiation
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
intestinal epithelial cell development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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