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Proteintech
KLHL12 Polyclonal Antibody
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Product Details
14883-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLHL12 Fusion Protein Ag6658 (217-568 aa encoded by BC004175)
Conjugate
Form
Liquid
Concentration
0.36 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: NLLQYVRMP LLTPRYITDV IDAEPFIRCS LQCRDLVDEA KKFHLRPELR SQMQGPRTRA RLGANEVLLV VGGFGSQQSP IDVVEKYDPK TQEWSFLPSI TRKRRYVASV SLHDRIYVIG GYDGRSRLSS VECLDYTADE DGVWYSVAPM NVRRGLAGAT TLGDMIYVSG GFDGSRRHTS MERYDPNIDQ WSMLGDMQTA REGAGLVVAS GVIYCLGGYD GLNILNSVEK YDPHTGHWTN VTPMATKRSG AGVALLNDHI YVVGGFDGTA HLSSVEAYNI RTDSWTTVTS MTTPRCYVGA TVLRGRLYAI AGYDGNSLLS SIECYDPIID SWEVVTSMGT QRCDAGVCVL REK (217-568 aa encoded by BC004175)
Target Information
Serves as a substrate-specific adapter for the CUL3-based ubiquitin-protein E3 ligase complex. Negatively regulates the Wnt signaling pathway via the targeted ubiquitination and subsequent proteolysis of DVL3.Tissue specificity: Highly expressed in testis and at lower levels in the submandibular salivary gland.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: CUL3-interacting protein 1; DKIR homolog; FLJ27152; hDKIR; kelch-like 12; kelch-like family member 12; Kelch-like protein 12; kelch-like protein C3IP1
Gene Aliases: C3IP1; DKIR; KLHL12
UniProt ID: (Human) Q53G59, (Mouse) Q8BZM0, (Rat) Q8R2H4
Entrez Gene ID: (Human) 59349, (Mouse) 240756, (Rat) 266772
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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