Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: GGVMYISGG ITHDTFQKEL MCFDPDTDKW IQKAPMTTVR GLHCMCTVGE RLYVIGGNHF RGTSDYDDVL SCEYYSPILD QWTPIAAMLR GQSDVGVAVF ENKIYVVGGY SWNNRCMVEI VQKYDPDKDE WHKVFDLPES LGGIRACTLT VFPPEETTPS PSRESPLSAP (487-655 aa encoded by BC008729)
This gene encodes a BTB and kelch domain containing protein and belongs to the kelch repeat domain containing superfamily of proteins. The encoded protein functions as an adaptor protein that complexes with Cullin 3 and other proteins to form the Cullin 3-based E3 ubiquitin-protein ligase complex. This complex is necessary for proper chromosome segregation and completion of cytokinesis. Alternate splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: BTB and kelch domain containing 2; BTB and kelch domain-containing protein 2; FLJ10262; kelch-like 13; kelch-like family member 13; Kelch-like protein 13; MGC74791
Gene Aliases: 1200009K10Rik; AI451128; BKLHD2; D130072F20Rik; KIAA1309; KLHL13; mKIAA1309
UniProt ID: (Human) Q9P2N7, (Mouse) Q80TF4
Entrez Gene ID: (Human) 90293, (Rat) 313445, (Mouse) 67455
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support