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Recommended positive controls: 293T.
Predicted reactivity: Mouse (91%), Zebrafish (81%), Xenopus laevis (82%), Chicken (83%), Bovine (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a BTB and kelch domain containing protein and belongs to the kelch repeat domain containing superfamily of proteins. The encoded protein functions as an adaptor protein that complexes with Cullin 3 and other proteins to form the Cullin 3-based E3 ubiquitin-protein ligase complex. This complex is necessary for proper chromosome segregation and completion of cytokinesis. Alternate splicing results in multiple transcript variants.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: BTB and kelch domain containing 2; BTB and kelch domain-containing protein 2; FLJ10262; kelch-like 13; kelch-like family member 13; Kelch-like protein 13; MGC74791
Gene Aliases: BKLHD2; KIAA1309; KLHL13
UniProt ID: (Human) Q9P2N7
Entrez Gene ID: (Human) 90293
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