Product References
COP9 signalosome deletion promotes renal injury and distal convoluted tubule remodeling.
American journal of physiology. Renal physiology
Cornelius RJ,Nelson JW,Su XT,Yang CL,Ellison DH
Fri Jul 01 00:00:00 UTC 2022
UBR5 is a novel regulator of WNK1 stability.
American journal of physiology. Cell physiology
Jung JU,B Ghosh A,Earnest S,Deaton SL,Cobb MH
Wed Jun 01 00:00:00 UTC 2022
KLHL3 deficiency in mice ameliorates obesity, insulin resistance, and nonalcoholic fatty liver disease by regulating energy expenditure.
Experimental & molecular medicine
Jang JH,Lee JW,Cho MJ,Hwang B,Kwon MG,Kim DH,Lee NK,Lee J,Park YJ,Yang YR,Kim J,Kim YH,An TH,Oh KJ,Bae KH,Park JG,Min JK
Mon Aug 01 00:00:00 UTC 2022
KLHL3 deficiency in mice ameliorates obesity, insulin resistance, and nonalcoholic fatty liver disease by regulating energy expenditure.
Experimental & molecular medicine
Jang JH,Lee JW,Cho MJ,Hwang B,Kwon MG,Kim DH,Lee NK,Lee J,Park YJ,Yang YR,Kim J,Kim YH,An TH,Oh KJ,Bae KH,Park JG,Min JK
Mon Aug 01 00:00:00 UTC 2022
KLHL3 deficiency in mice ameliorates obesity, insulin resistance, and nonalcoholic fatty liver disease by regulating energy expenditure.
Experimental & molecular medicine
Jang JH,Lee JW,Cho MJ,Hwang B,Kwon MG,Kim DH,Lee NK,Lee J,Park YJ,Yang YR,Kim J,Kim YH,An TH,Oh KJ,Bae KH,Park JG,Min JK
Mon Aug 01 00:00:00 UTC 2022
KLHL3 deficiency in mice ameliorates obesity, insulin resistance, and nonalcoholic fatty liver disease by regulating energy expenditure.
Experimental & molecular medicine
Jang JH,Lee JW,Cho MJ,Hwang B,Kwon MG,Kim DH,Lee NK,Lee J,Park YJ,Yang YR,Kim J,Kim YH,An TH,Oh KJ,Bae KH,Park JG,Min JK
Mon Aug 01 00:00:00 UTC 2022
Combined Kelch-like 3 and Cullin 3 Degradation is a Central Mechanism in Familial Hyperkalemic Hypertension in Mice.
Journal of the American Society of Nephrology : JASN
Maeoka Y,Ferdaus MZ,Cornelius RJ,Sharma A,Su XT,Miller LN,Robertson JA,Gurley SB,Yang CL,Ellison DH,McCormick JA
Tue Mar 01 00:00:00 UTC 2022
Combined Kelch-like 3 and Cullin 3 Degradation is a Central Mechanism in Familial Hyperkalemic Hypertension in Mice.
Journal of the American Society of Nephrology : JASN
Maeoka Y,Ferdaus MZ,Cornelius RJ,Sharma A,Su XT,Miller LN,Robertson JA,Gurley SB,Yang CL,Ellison DH,McCormick JA
Tue Mar 01 00:00:00 UTC 2022
A viral interferon regulatory factor degrades RNA-binding protein hnRNP Q1 to enhance aerobic glycolysis via recruiting E3 ubiquitin ligase KLHL3 and decaying GDPD1 mRNA.
Cell death and differentiation
Qi X,Yan Q,Shang Y,Zhao R,Ding X,Gao SJ,Li W,Lu C
Tue Nov 01 00:00:00 UTC 2022
A viral interferon regulatory factor degrades RNA-binding protein hnRNP Q1 to enhance aerobic glycolysis via recruiting E3 ubiquitin ligase KLHL3 and decaying GDPD1 mRNA.
Cell death and differentiation
Qi X,Yan Q,Shang Y,Zhao R,Ding X,Gao SJ,Li W,Lu C
Tue Nov 01 00:00:00 UTC 2022
Renal COP9 Signalosome Deficiency Alters CUL3-KLHL3-WNK Signaling Pathway.
Journal of the American Society of Nephrology : JASN
Cornelius RJ,Si J,Cuevas CA,Nelson JW,Gratreak BDK,Pardi R,Yang CL,Ellison DH
Thu Nov 01 00:00:00 UTC 2018
Renal COP9 Signalosome Deficiency Alters CUL3-KLHL3-WNK Signaling Pathway.
Journal of the American Society of Nephrology : JASN
Cornelius RJ,Si J,Cuevas CA,Nelson JW,Gratreak BDK,Pardi R,Yang CL,Ellison DH
Thu Nov 01 00:00:00 UTC 2018
Decreased KLHL3 expression is involved in the pathogenesis of pseudohypoaldosteronism type II caused by cullin 3 mutation in vivo.
Clinical and experimental nephrology
Yoshida S,Araki Y,Mori T,Sasaki E,Kasagi Y,Isobe K,Susa K,Inoue Y,Bomont P,Okado T,Rai T,Uchida S,Sohara E
Sat Dec 01 00:00:00 UTC 2018
Decreased KLHL3 expression is involved in the pathogenesis of pseudohypoaldosteronism type II caused by cullin 3 mutation in vivo.
Clinical and experimental nephrology
Yoshida S,Araki Y,Mori T,Sasaki E,Kasagi Y,Isobe K,Susa K,Inoue Y,Bomont P,Okado T,Rai T,Uchida S,Sohara E
Sat Dec 01 00:00:00 UTC 2018
KLHL3 Knockout Mice Reveal the Physiological Role of KLHL3 and the Pathophysiology of Pseudohypoaldosteronism Type II Caused by Mutant KLHL3.
Molecular and cellular biology
Sasaki E,Susa K,Mori T,Isobe K,Araki Y,Inoue Y,Yoshizaki Y,Ando F,Mori Y,Mandai S,Zeniya M,Takahashi D,Nomura N,Rai T,Uchida S,Sohara E
Sat Apr 01 00:00:00 UTC 2017
KLHL3 Knockout Mice Reveal the Physiological Role of KLHL3 and the Pathophysiology of Pseudohypoaldosteronism Type II Caused by Mutant KLHL3.
Molecular and cellular biology
Sasaki E,Susa K,Mori T,Isobe K,Araki Y,Inoue Y,Yoshizaki Y,Ando F,Mori Y,Mandai S,Zeniya M,Takahashi D,Nomura N,Rai T,Uchida S,Sohara E
Sat Apr 01 00:00:00 UTC 2017
cMyBP-C was decreased via KLHL3-mediated proteasomal degradation in congenital heart diseases.
Experimental cell research
Wang L,Lai G,Chu G,Liang X,Zhao Y
Thu Jun 01 00:00:00 UTC 2017
cMyBP-C was decreased via KLHL3-mediated proteasomal degradation in congenital heart diseases.
Experimental cell research
Wang L,Lai G,Chu G,Liang X,Zhao Y
Thu Jun 01 00:00:00 UTC 2017
cMyBP-C was decreased via KLHL3-mediated proteasomal degradation in congenital heart diseases.
Experimental cell research
Wang L,Lai G,Chu G,Liang X,Zhao Y
Thu Jun 01 00:00:00 UTC 2017
cMyBP-C was decreased via KLHL3-mediated proteasomal degradation in congenital heart diseases.
Experimental cell research
Wang L,Lai G,Chu G,Liang X,Zhao Y
Thu Jun 01 00:00:00 UTC 2017
Kelch-Like Protein 2 Mediates Angiotensin II-With No Lysine 3 Signaling in the Regulation of Vascular Tonus.
Journal of the American Society of Nephrology : JASN
Zeniya M,Morimoto N,Takahashi D,Mori Y,Mori T,Ando F,Araki Y,Yoshizaki Y,Inoue Y,Isobe K,Nomura N,Oi K,Nishida H,Sasaki S,Sohara E,Rai T,Uchida S
Tue Sep 01 00:00:00 UTC 2015
Kelch-Like Protein 2 Mediates Angiotensin II-With No Lysine 3 Signaling in the Regulation of Vascular Tonus.
Journal of the American Society of Nephrology : JASN
Zeniya M,Morimoto N,Takahashi D,Mori Y,Mori T,Ando F,Araki Y,Yoshizaki Y,Inoue Y,Isobe K,Nomura N,Oi K,Nishida H,Sasaki S,Sohara E,Rai T,Uchida S
Tue Sep 01 00:00:00 UTC 2015
Involvement of selective autophagy mediated by p62/SQSTM1 in KLHL3-dependent WNK4 degradation.
The Biochemical journal
Mori Y,Mori T,Wakabayashi M,Yoshizaki Y,Zeniya M,Sohara E,Rai T,Uchida S
Sun Nov 15 00:00:00 UTC 2015
Impaired degradation of WNK by Akt and PKA phosphorylation of KLHL3.
Biochemical and biophysical research communications
Yoshizaki Y,Mori Y,Tsuzaki Y,Mori T,Nomura N,Wakabayashi M,Takahashi D,Zeniya M,Kikuchi E,Araki Y,Ando F,Isobe K,Nishida H,Ohta A,Susa K,Inoue Y,Chiga M,Rai T,Sasaki S,Uchida S,Sohara E
Fri Nov 13 00:00:00 UTC 2015
Impaired degradation of WNK by Akt and PKA phosphorylation of KLHL3.
Biochemical and biophysical research communications
Yoshizaki Y,Mori Y,Tsuzaki Y,Mori T,Nomura N,Wakabayashi M,Takahashi D,Zeniya M,Kikuchi E,Araki Y,Ando F,Isobe K,Nishida H,Ohta A,Susa K,Inoue Y,Chiga M,Rai T,Sasaki S,Uchida S,Sohara E
Fri Nov 13 00:00:00 UTC 2015
Impaired degradation of WNK1 and WNK4 kinases causes PHAII in mutant KLHL3 knock-in mice.
Human molecular genetics
Susa K,Sohara E,Rai T,Zeniya M,Mori Y,Mori T,Chiga M,Nomura N,Nishida H,Takahashi D,Isobe K,Inoue Y,Takeishi K,Takeda N,Sasaki S,Uchida S
Wed Oct 01 00:00:00 UTC 2014
Impaired degradation of WNK1 and WNK4 kinases causes PHAII in mutant KLHL3 knock-in mice.
Human molecular genetics
Susa K,Sohara E,Rai T,Zeniya M,Mori Y,Mori T,Chiga M,Nomura N,Nishida H,Takahashi D,Isobe K,Inoue Y,Takeishi K,Takeda N,Sasaki S,Uchida S
Wed Oct 01 00:00:00 UTC 2014
KLHL3 mutations cause familial hyperkalemic hypertension by impairing ion transport in the distal nephron.
Nature genetics
Louis-Dit-Picard H,Barc J,Trujillano D,Miserey-Lenkei S,Bouatia-Naji N,Pylypenko O,Beaurain G,Bonnefond A,Sand O,Simian C,Vidal-Petiot E,Soukaseum C,Mandet C,Broux F,Chabre O,Delahousse M,Esnault V,Fiquet B,Houillier P,Bagnis CI,Koenig J,Konrad M,Landais P,Mourani C,Niaudet P,Probst V,Thauvin C,Unwin RJ,Soroka SD,Ehret G,Ossowski S,Caulfield M,Bruneval P,Estivill X,Froguel P,Hadchouel J,Schott JJ,Jeunemaitre X
Sun Mar 11 00:00:00 UTC 2012
KLHL3 mutations cause familial hyperkalemic hypertension by impairing ion transport in the distal nephron.
Nature genetics
Louis-Dit-Picard H,Barc J,Trujillano D,Miserey-Lenkei S,Bouatia-Naji N,Pylypenko O,Beaurain G,Bonnefond A,Sand O,Simian C,Vidal-Petiot E,Soukaseum C,Mandet C,Broux F,Chabre O,Delahousse M,Esnault V,Fiquet B,Houillier P,Bagnis CI,Koenig J,Konrad M,Landais P,Mourani C,Niaudet P,Probst V,Thauvin C,Unwin RJ,Soroka SD,Ehret G,Ossowski S,Caulfield M,Bruneval P,Estivill X,Froguel P,Hadchouel J,Schott JJ,Jeunemaitre X
Sun Mar 11 00:00:00 UTC 2012
