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Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL42) E3 ubiquitin ligase complex mediates the ubiquitination and subsequent degradation of KATNA1. Involved in microtubule dynamics throughout mitosis. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Ctb9; Cullin-3-binding protein 9; kelch domain containing 5; Kelch domain-containing protein 5; kelch-like family member 42; kelch-like family, member 42; Kelch-like protein 42
Gene Aliases: A330079N23Rik; AI450355; C230080I20Rik; Ctb9; KIAA1340; KLHDC5; KLHL42; mKIAA1340
UniProt ID: (Human) Q9P2K6, (Mouse) Q8BFQ9
Entrez Gene ID: (Human) 57542, (Mouse) 232539
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