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Immunogen sequence: QIINGEDCSP HSQPWQAALV MENELFCSGV LVHPQWVLSA AHCFQNSYTI GLGLHSLEAD QEPGSQMVEA SLSVRHPEYN RPLLANDLML IKLDESVSES DTIRSISIAS QCPTAGNSCL VSGWGLLANG RMPTVLQCVN VSVVSEEVCS KLYDPLYHPS MFCAGGGQDQ KDSCNGDSGG PLICNGYLQG LVSFGKAPCG QVGVPGVYTN LCKFTEWIEK TVQAS
Kallikreins are a subgroup of serine proteases and are implicated in carcinogenesis. A novel Kallikrein gene Prostase/KLK-L1 (also known as KLK4) is expressed and is up-regulated by androgens and progestins. KLK-L1 may be involved in the pathogenesis and/or progression of prostate, breast, and possibly other malignancies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: androgen-regulated message 1; enamel matrix serine protease 1; Enamel matrix serine proteinase 1; kallikrein 4 (prostase, enamel matrix, prostate); Kallikrein-4; Kallikrein-like protein 1; kallikrein-related peptidase 4; KLK-4; KLK-L1; KLKL1; Prostase; protease, serine 17 (enamel matrix, prostate); Serine protease 17
Gene Aliases: AI2A1; ARM1; EMSP; EMSP1; ESMP1; kallikrein; KLK-L1; KLK4; PRSS17; PSTS
UniProt ID: (Human) Q9Y5K2, (Mouse) Q9Z0M1
Entrez Gene ID: (Human) 9622, (Mouse) 56640, (Rat) 408210
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