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Positive Control:Human skin tissue (IHC). MCF-7 cell lysates.
Cellular Location: Secreted.
Kallikreins are a subgroup of serine proteases and are implicated in carcinogenesis. A novel Kallikrein gene Prostase/KLK-L1 (also known as KLK4) is expressed and is up-regulated by androgens and progestins. KLK-L1 may be involved in the pathogenesis and/or progression of prostate, breast, and possibly other malignancies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: androgen-regulated message 1; enamel matrix serine protease 1; Enamel matrix serine proteinase 1; Kallikrein-4; Kallikrein-like protein 1; kallikrein-related peptidase 4; KLK-4; KLK-L1; KLKL1; Prostase; Serine protease 17
Gene Aliases: AI2A1; ARM1; EMSP; EMSP1; kallikrein; KLK-L1; KLK4; PRSS17; PSTS
UniProt ID: (Human) Q9Y5K2
Entrez Gene ID: (Human) 9622
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