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Invitrogen
KLRC2/KLRC4 Polyclonal Antibody
Product Details
PA5-99852
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human KLRC2(Accession P26717), corresponding to amino acid residues M1-Q40.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2818785
Product Specific Information
Antibody detects endogenous levels of total KLRC2/4.
Target Information
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. The group, designated KLRC (NKG2) are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The KLRC (NKG2) gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. KLRC2 alternative splice variants have been described but their full-length nature has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD159 antigen-like family member C; CD159c; killer cell lectin-like receptor subfamily C, member 2; killer cell lectin-like receptor subfamily C, member 4; natual killer cell group 2-F; NK cell receptor C; NK cell receptor F; NKG2-C type II integral membrane protein; NKG2-C-activating NK receptor; NKG2-F type II integral membrane protein; NKG2-F-activating NK receptor
Gene Aliases: CD159c; KLRC2; KLRC4; NKG2-C; NKG2-F; NKG2C; Nkg2E; NKG2F; rNKG2C
UniProt ID: (Human) P26717, (Human) O43908
Entrez Gene ID: (Human) 3822, (Human) 8302, (Rat) 29684, (Mouse) 16642
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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