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Product Details
H00008302-M03
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
1D10
Immunogen
KLRC4 (AAH17784, 1 a.a. approximately 158 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
Immunogen sequence: MNKQRGTYSE VSLAQDPKRQ QRKLKGNKIS ISGTKQEIFQ VELNLQNASS DHQGNDKTYH CKGLLPPPEK LTAEVLGIIC IVLMATVLKT IVLIPCIGVL EQNNFSLNRR MQKARHCGHC PEEWITYSNS CYYIGKERRT WEERVCWPVL RRTLICFL
Target Information
The KLRC4 (Killer Cell Lectin Like Receptor C4) gene encodes a member of the NKG2 family of receptors, which are expressed mostly on natural killer (NK) cells and some T lymphocytes. This gene is located on chromosome 12 and plays a key role in immune surveillance and the activation of NK cells. The KLRC4 protein, also known as NKG2F, interacts with other receptors such as KLRK1 (NKG2D) to recognize stress-induced ligands on potential target cells, thereby mediating their destruction. Variants and polymorphisms in KLRC4 have been investigated in various immune-related conditions, including their association with thyroid diseases and cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: killer cell lectin-like receptor subfamily C, member 4; natual killer cell group 2-F; NK cell receptor F; NKG2-F type II integral membrane protein; NKG2-F-activating NK receptor
Gene Aliases: KLRC4; NKG2-F; NKG2F
UniProt ID: (Human) O43908
Entrez Gene ID: (Human) 8302
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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