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Invitrogen
KNT1 Polyclonal Antibody
FIGURE: 1 / 6
KNT1 Antibody (PA5-119465) in IHC (P)
Immunohistochemistry analysis of Kininogen 1 in paraffin-embedded Rat Stomach tissue. Samples were incubated with polyclonal antibody (Product # PA5-119465) at a dilution of 10 µg/mL, followed by HRP-Linked Caprine Anti-Rabbit IgG using a dilution of 2 µg/mL.
Product Details
PA5-119465
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein T-Kininogen 1. The antigen corresponds to amino acid range 378-430 of the target protein.
Conjugate
Form
Liquid
Concentration
500 µg/mL
Purification
Protein A/G
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2903963
Target Information
KNT1 (T-Kinninogen 1) is the acute phase kininogen of the rat. KNT1 could be a healing protein because of its properties as a cysteine protease inhibitor. Evidence has been presented that mRNA of T-kininogen synthesis may be a function of interleukin 6 production. In rats, four types of kininogens are produced, two of which are classical high and low molecular weight kininogens and two of which are low molecular weight-like kininogens, designated T-kininogen 1 and T-kininogen 2. T-kininogen 1 and T-kininogen 2 are 430 amino acid secreted rat proteins that each contain three cystatin domains and have nearly identical functions. Existing in plasma, both T-kininogen 1 and T-kininogen 2 are glycoproteins that act as thiol protease inhibitors and also play a role in blood coagulation, specifically by helping to optimally position blood coagulation factors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Alpha-1-MAP; low molecular weight (LMW) T-kininogen II; Major acute phase protein; major acute phase protein (alpha-1-MAP); T-kininogen 2; T-kininogen II; T-Kinninogen 1; Thiostatin
Gene Aliases: kininogen
UniProt ID: (Rat) P08932
Entrez Gene ID: (Rat) 288001
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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