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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • KPNA2 Antibodies

          Proteintech

          KPNA2 Polyclonal Antibody

          39 References
          View all (23) KPNA2 antibodies

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          Datasheet
          Protocols
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          Datasheet
          Protocols
          Questions & Answers

          Cite KPNA2 Polyclonal Antibody

          • Antibody Testing Data (8)
          KPNA2 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.
          KPNA2 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 8

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          KPNA2 Antibody (10819-1-AP) in ICC/IF

          Immunofluorescent analysis of ( 10% Formaldehyde ) fixed HepG2 cells using 10819-1-AP (KPNA2 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          KPNA2 Antibody in Immunocytochemistry (ICC/IF)
          KPNA2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          KPNA2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          KPNA2 Antibody in Western Blot (WB)
          KPNA2 Antibody in Western Blot (WB)
          KPNA2 Antibody in Western Blot (WB)
          KPNA2 Antibody in Western Blot (WB)
          KPNA2 Antibody in Western Blot (WB)

          Product Details

          10819-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:2,000
          View 20 publications 20 publications

          Immunohistochemistry (IHC)

          -
          View 10 publications 10 publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:20-1:400
          -

          Immunocytochemistry (ICC/IF)

          1:20-1:200
          View 5 publications 5 publications

          Immunoprecipitation (IP)

          Assay-dependent
          View 4 publications 4 publications
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Published species

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          KPNA2 Fusion Protein Ag1153 (230-529 aa encoded by BC005978)
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.19 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Product Specific Information

          Immunogen sequence: TWTLSNLCR NKNPAPPIDA VEQILPTLVR LLHHDDPEVL ADTCWAISYL TDGPNERIGM VVKTGVVPQL VKLLGASELP IVTPALRAIG NIVTGTDEQT QVVIDAGALA VFPSLLTNPK TNIQKEATWT MSNITAGRQD QIQQVVNHGL VPFLVSVLSK ADFKTQKEAV WAVTNYTSGG TVEQIVYLVH CGIIEPLMNL LTAKDTKIIL VILDAISNIF QAAENLGETE KLSIMIEECG GLDKIEALQN HENESVYKAS LSLIEKYFSV EEEEDQNVVP ETTSEGYTFQ VQDGAPGTFN F (230-529 aa encoded by BC005978)

          Target Information

          The import of proteins into the nucleus is a process that involves at least 2 steps. The first is an energy-independent docking of the protein to the nuclear envelope and the second is an energy-dependent translocation through the nuclear pore complex. Imported proteins require a nuclear localization sequence which generally consists of a short region of basic amino acids or 2 such regions spaced about 10 amino acids apart. Proteins involved in the first step of nuclear import have been identified in different systems. These include the Xenopus protein importin and its yeast homolog, SRP1, which bind to the NLS. KPNA2 protein interacts with the NLSs of DNA helicase Q1 and SV40 T antigen and may be involved in the nuclear transport of proteins. KPNA2 also may play a role in VJ recombination.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: IMA2; importin alpha 2; Importin alpha P1; Importin subunit alpha-1; importin subunit alpha-2; importin-alpha-P1; IPOA 1; IPOA1 QIP2; karyopherin (importin) alpha 2; Karyopherin A2; karyopherin alpha 2 (RAG cohort 1, importin alpha 1); Karyopherin subunit alpha-2; m-importin-alpha-P1; nuclear import protein; Pendulin; Pore targeting complex 58 kDa subunit; PTAC58; RAG cohort 1; RAG cohort protein 1; RCH 1; SRP 1; SRP1 alpha; SRP1-alpha

          View more View less

          Gene Aliases: 2410044B12Rik; importin; IPOA1; KPNA2; PTAC58; QIP2; RCH1; SRP1; SRP1-alpha; SRP1alpha

          View more View less

          UniProt ID: (Human) P52292, (Mouse) P52293

          View more View less

          Entrez Gene ID: (Human) 3838, (Mouse) 16647, (Rat) 85245

          View more View less

          Function(s)
          protein binding nuclear localization sequence binding protein transporter activity histone deacetylase binding poly(A) RNA binding
          Process(es)
          protein import into nucleus NLS-bearing protein import into nucleus intracellular protein transport regulation of transcription by glucose regulation of DNA recombination DNA metabolic process modulation by virus of host process intracellular transport of virus
          It has to be done as per old AB suggested Products section.
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