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Positive Samples: BT-474, Jurkat, A-549, U-251MG, HeLa
Immunogen sequence: MAENPSLENH RIKSFKNKGR DVETMRRHRN EVTVELRKNK RDEHLLKKRN VPQEESLEDS DVDADFKAQN VTLEAILQNA TSDNPVVQLS AVQAARKLLS SDRNPPIDDL IKSGILPILV KCLERDDNPS LQFEAAWALT NIASGTSAQT QAVVQSNAVP LFLRLLRSPH QNVCEQAVWA LGNIIGDGPQ CRDYVISLGV VKPLLSFISP
The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC), which consists of 60-100 proteins. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion while larger molecules are transported by an active process. The protein encoded by this gene belongs to the importin alpha family, and is involved in nuclear protein import.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: importin alpha 4; Importin alpha Q2; importin alpha-3; importin subunit alpha-3; Importin subunit alpha-4; importin-alpha-Q2; karyopherin (importin) alpha 3; karyopherin alpha 3 (importin alpha 4); Karyopherin subunit alpha-3; predicted role in nuclear import; Qip2; RP11-432M24.3; SRP1-gamma
Gene Aliases: hSRP1; importin; IPOA4; KPNA3; QIP2; SRP1; SRP1gamma; SRP4
UniProt ID: (Human) O00505, (Mouse) O35344
Entrez Gene ID: (Human) 3839, (Mouse) 16648, (Rat) 361055
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