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Immunogen sequence: FLLSGNDPAI HLYKENEGLH QFEEQPVENL FPELTNLTSS VLWLDVHNFP GTSRRLSALG CQSGYVRVAH VDQRSREVLQ MWSVL
Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 88%.
Kaptin, also named as KPTN and Actin-associated protein 2E4, originally isolated from human blood platelets and likely to be involved in the actin rearrangements occurring during activation. It plays a unique role in the actin rearrangements that accompany platelet activation and stereocilia formation. Kaptin is necessary for normal neuromorphogenesis. It may play a role in producing the sensory apparatus in hair cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Actin-associated protein 2E4; actin-binding protein; kaptin; kaptin (actin binding protein); KICSTOR complex protein kaptin
Gene Aliases: 2310042D10Rik; 2E4; C030013F01Rik; KPTN; MRT41
UniProt ID: (Human) Q9Y664
Entrez Gene ID: (Human) 11133, (Mouse) 70394, (Rat) 308107
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