Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
KRT81 Polyclonal Antibody
Promotion
View available promotion(s)
Promo code: {{promo.promoCode}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
FIGURE: 1 / 1
KRT81 Antibody (PA5-92102) in WB
Western blot analysis of KRT81 in extracts of various cell lines. Samples were incubated with KRT81 Polyclonal antibody (Product # PA5-92102) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
Product Details
PA5-92102
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 350-450 of human KRT81 (NP_0022722)
Conjugate
Form
Liquid
Concentration
1.08 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2806379
Product Specific Information
Immunogen sequence: VAQSEQQGEA ALSDARCKLA ELEGALQKAK QDMACLIREY QEVMNSKLGL DIEIATYRRL LEGEEQRLCE GIGAVNVCVS SSRGGVVCGD LCVSGSRPVT G
Positive Samples: Raji, A-549
Target Information
The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB3 and KRTHB6, is found primarily in the hair cortex. Mutations in this gene and KRTHB6 have been observed in patients with a rare dominant hair disease, monilethrix.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: ghHb1; ghHKb1; Hair keratin K2.9; hard keratin, type II, 1; K81; keratin 81, type II; keratin complex 2, basic, gene 19; Keratin, hair, basic, 1; Keratin, type II cuticular Hb1; Keratin-81; krt81; Metastatic lymph node 137 gene protein; MLN 137; Type II hair keratin Hb1; Type-II keratin Kb21
Gene Aliases: AA589625; ghHkb1; Hb-1; HB1; hHAKB2-1; Krt2-19; KRT81; KRTHB1; MLN137
UniProt ID: (Human) Q14533, (Mouse) Q9ERE2
Entrez Gene ID: (Human) 3887, (Mouse) 64818
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support