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The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB1 and KRTHB6, is found primarily in the hair cortex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: hair keratin; Hair keratin K2.11; Hair keratin K211; hard keratin, type II, 6; K86; keratin 86, type II; keratin protein HB6; keratin, hair, basic, 6 (monilethrix); Keratin, type II cuticular Hb6; Keratin-86; Type II hair keratin Hb6; Type-II keratin Kb26
Gene Aliases: Hb1; HB6; K86; KRT86; KRTHB1; KRTHB6; MNX
UniProt ID: (Human) O43790
Entrez Gene ID: (Human) 3892
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