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Invitrogen
KV1.1 (KCNA1) Polyclonal Antibody
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FIGURE: 1 / 1
KV1.1 (KCNA1) Antibody (PA5-95168) in WB
Western blot analysis of KV1.1 (KCNA1) in Lane 1: rat brain tissue lysate (40 µg), Lane 2: rat testis tissue lysate (40 µg), Lane 3: rat cardiac muscle tissue lysate (40 µg), Lane 4: HeLa whole cell lysate (40 µg), Lane 5: U87 whole cell lysate (40 µg), Lane 6: SHG whole cell lysate (40 µg), Lane 7: NEURO whole cell lysate (40 µg). Samples were incubated with KV1.1 (KCNA1) polyclonal antibody (Product # PA5-95168).
Product Details
PA5-95168
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human Kv1.1 potassium channel (465-481aa IAHYRQVNIRTANCTTA).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 5mg BSA
Contains
0.05mg sodium azide, 0.05mg thimerosal
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2806973
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: Rat Brain Tissue, Rat Testis Tissue, Rat Cardiac Muscle Tissue, HELA whole cell, U87 whole cell, SHG whole cell, NEURO whole cell.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Target Information
This gene encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. The encoded protein has six putative transmembrane segments, and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif. The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: brain potassium channel protein-1; IA; MBK1; megencephaly; MGC126782; MGC138385; MKI; potassium (K+) channel protein voltage dependent; potassium channel, voltage gated shaker related subfamily A, member 1; potassium voltage gated channel shaker related subfamily member 1; potassium voltage gated channel, shaker related subfamily, member 1; Potassium voltage-gated channel subfamily A member 1; potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia); RBKI; RCK1; Voltage-gated K(+) channel HuKI; Voltage-gated potassium channel HBK1; Voltage-gated potassium channel subunit Kv1.1
Gene Aliases: AEMK; AI840627; EA1; HBK1; HUK1; Kca1-1; Kcna; KCNA1; Kcpvd; KV1.1; MBK1; mceph; Mk-1; MK1; RBK1; Shak
UniProt ID: (Human) Q09470, (Mouse) P16388, (Rat) P10499
Entrez Gene ID: (Human) 3736, (Mouse) 16485, (Rat) 24520
startle response
potassium ion transport
regulation of muscle contraction
chemical synaptic transmission
neuroblast proliferation
cell communication by electrical coupling
magnesium ion homeostasis
neuronal action potential
hippocampus development
neuronal signal transduction
cellular protein localization
regulation of ion transmembrane transport
regulation of membrane potential
neuromuscular process
detection of mechanical stimulus involved in sensory perception of pain
detection of mechanical stimulus involved in sensory perception of touch
protein homooligomerization
cellular response to magnesium ion
potassium ion transmembrane transport
transport
ion transport
brain development
transmembrane transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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