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Invitrogen
Kallikrein 11 (Cleaved Ile54) Polyclonal Antibody
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FIGURE: 1 / 2
Kallikrein 11 (Cleaved Ile54) Antibody (PA5-37436) in WB
Western blot analysis of Kallikrein 11 (Cleaved Ile54) in Lane 1: C6 whole cell lysate (40 µg), Lane 2: BV2 whole cell lysate (40 µg), Lane 3: U-87MG whole cell lysate (40 µg), Lane 4: A2780 whole cell lysate (40 µg). Samples were incubated with Kallikrein 11 (Cleaved Ile54) polyclonal antibody (Product # PA5-37436) at a dilution of 1:500.
Product Details
PA5-37436
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to amino acids 23-71 of human Cleaved-KLK11
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2554060
Product Specific Information
This antibody detects endogenous protein at a molecular weight of 25 and 31 kDa.
Purity is >95% by SDS-PAGE.
Target Information
Kallikreins (KLKs) belong to the serine protease family of proteolytic enzymes. Human pancreatic/renal KLK encodes for the KLK1 enzyme, which is involved in post-translational processing of polypeptide precursors. The function of the other members of KLK gene family is currently unknown, but evidence suggests that many KLKs are implicated in carcinogenesis. The human KLK gene family consists of 15 serine proteases. The human KLK genes are clustered on chromosome 19q13. Unlike other kalllikreins, the KLK4-15 encoded proteases are less related and do not contain a conventional KLK loop. Clusters of genes exhibit high prostatic (KLK2-4, KLK15) or pancreatic (KLK6-13) expression . KLK2 is also known as glandular kallikrein 2, tissue kallikrein or HGK-1, and KLK3 is known as prostate-specific antigen (PSA). Both KLK2 and KLK3 have important applications in prostate cancer and breast cancer diagnostics. KLK4, KLK5, KLK9, KLK13, KLK12 and KLK14 have been previously known as KLK-L1, KLK-L2, KLK-L3, KLK-L4, KLK-L5 and KLK-L6, respectively.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Hippostasin; hK11; kallikrein 11; Kallikrein-11; kallikrein-related peptidase 11; Kallikrein11; protease, serine, 20; Serine protease 20; Trypsin-like protease
Gene Aliases: 2310015I08Rik; KLK11; PRSS20; TLSP; UNQ649/PRO1279
UniProt ID: (Human) Q9UBX7, (Mouse) Q9QYN3
Entrez Gene ID: (Human) 11012, (Rat) 292849, (Mouse) 56538
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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