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Proteintech
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Immunogen sequence: MGRPRPRAA KTWMFLLLLG GAWAGHSRAQ EDKVLGGHEC QPHSQPWQAA LFQGQQLLCG GVLVGGNWVL TAAHCKKPKY TVRLGDHSLQ NKDGPEQEIP VVQSIPHPCY NSSDVEDHNH DLMLLQLRDQ ASLGSKVKPI SLADHCTQPG QKCTVSGWGT VTSPRENFPD TLNCAEVKIF PQKKCEDAYP GQITDVMVCA GSSKGADTCQ GDSGGPLVCD GALQGITSWG SDPCGRSDKP GVYTNICRYL DWIKKIIGSK G (1-260 aa encoded by BC040887)
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in tandem in a gene cluster on chromosome 19. The encoded protein may be involved in proteolytic cascade in the skin and may serve as a biomarker for ovarian cancer. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Brain Serine protease 1; H NRPN; hK8; kallikrein 8; kallikrein 8 (neuropsin/ovasin); Kallikrein-8; kallikrein-related peptidase 8; Kallikrein8; mK8; Neuropsin; NP; Ovasin; PRO322; protease, serine, 19 (neuropsin); Serine protease 19; Serine protease TADG-14; Tumor-associated differentially expressed gene 14 protein; UNQ283
Gene Aliases: BSP1; HNP; KLK8; NP; NRPN; PRSS19; TADG14; UNQ283/PRO322
UniProt ID: (Human) O60259, (Mouse) Q61955
Entrez Gene ID: (Human) 11202, (Rat) 308565, (Mouse) 259277
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