Invitrogen

Ki-67 Monoclonal Antibody (SolA15), FITC, eBioscience™

Ki-67 Antibody in Immunocytochemistry, Immunohistochemistry (Paraffin) (ICC/IF, IHC (P))

FIGURE: 1 / 96

Ki-67 Antibody (11-5698-82) in ICC/IF, IHC (P)

Frontiers in oncology 2020 - Figure 1 (A) Scheme of experiments. (B) Representative image (at 10X, transmitted light microscopy) of GBM143 xenograft line cultured for 3 weeks in vitro in media indicated; cells were collected and orthotopically implanted into cranially irradiated mice 24 hrs post-irradiation (IR). (C) Representative Immunofluorescence (IF) images (at 4X, tiling) for hLamin A+C staining from 0 Gy and 20 Gy-IR mice corona... View More

Ki-67 Antibody in Immunocytochemistry (ICC/IF)

Ki-67 Antibody in Immunocytochemistry, Flow Cytometry (ICC/IF, Flow)

Ki-67 Antibody in Immunohistochemistry, Flow Cytometry (IHC, Flow)

Ki-67 Antibody in Western Blot, Immunohistochemistry, Flow Cytometry (WB, IHC, Flow)

Ki-67 Antibody in Immunocytochemistry, Immunohistochemistry (ICC/IF, IHC)

Product Image Gallery

Ki-67 Antibody — Figure 6 Succinate is produced by Tritrichomonas and sufficient to activate the tuft cell - ILC2 circuit (A and B) GF mice monocolonized with Tritrichomonas and concentrations of acetate (A) and succinate (B) measured in the cecal content after 6 weeks. (C) Metabolite receptor mRNA expression quantified by qPCR in tuft cells versus other epithelial cells sorted from small intestine (SI) and normalized to levels in non-tuft epithelial cells. (D-F) Tritrichomonas -free IL-13-reporter (Sm13) mice were treated with succinate, acetate or a SCFA mix (acetate, butyrate, propionate) in drinking water for 4 days. Expression of Ki-67 and IL-13 by ILC2s in SI quantified by flow cytometry and representative dot plot from wild-type (WT) mice shown (D). Expression of Ki-67 (E) and IL-13 (F) by ILC2s from WT, Pou2f3 -/- , Il25 -/- and Trpm5 -/- mice treated with indicated solutions. (G) Tritrichomonas -free WT mice treated with 100 mM succinate in drinking water for 10 days. Frequencies of tuft cells in SI by flow cytometry. (H and I) Tritrichomonas -free A20 fl R+ and Il25 -/- A20 fl R+ mice treated with 100 mM succinate in drinking water for 25 days and frequencies of tuft cells (H) and SI length (I) analyzed. Data from one experiment (A, B) or from one experiment representative of at least two independent experiments (C, D, G-I) or pooled from multiple independent experiments (E, F). C, mean and s.e.m.; n = 3. **p < 0.01, ****p < 0.0001; ns, not significant by M {TM}

Product Details

11-5698-82

Applications

Tested Dilution

Publications

Western Blot (WB)

View 1 publication 1 publication

Immunohistochemistry (IHC)

Assay-Dependent

View 70 publications 70 publications

Immunohistochemistry (Paraffin) (IHC (P))

View 3 publications 3 publications

Immunohistochemistry (PFA fixed) (IHC (PFA))

View 2 publications 2 publications

Immunohistochemistry (Frozen) (IHC (F))

View 1 publication 1 publication

Immunocytochemistry (ICC/IF)

10 µg/mL

View 45 publications 45 publications

Flow Cytometry (Flow)

0.25 µg/test

View 113 publications 113 publications

Functional Assay (Functional)

View 1 publication 1 publication

Miscellaneous PubMed (MISC)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Dog, Cynomolgus monkey, Human, Mouse, Non-human primate, Rat

Published species

Guinea pig, Human, Mouse, Rat

Host/Isotype

Rat / IgG2a, kappa

Recommended Isotype Control

Rat IgG2a kappa Isotype Control (eBR2a), FITC, eBioscience™

Class

Monoclonal

Type

Antibody

Clone

SolA15

Conjugate

FITC FITC FITC

Excitation/Emission Max

498/517 nm View spectra

Form

Liquid

Concentration

0.5 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.2

Contains

0.09% sodium azide

Storage conditions

4°C, store in dark, DO NOT FREEZE!

Shipping conditions

Ambient (domestic); Wet ice (international)

AB_11151330

Product Specific Information

Description: The monoclonal antibody SolA15 recognizes mouse and rat Ki-67, a 300 kDa nuclear protein. Ki-67 is present during all active phases of the cell cycle (G1, S, G2, and mitosis), but is absent from resting cells (G0). Ki-67 is detected within the nucleus during interphase but redistributes to the chromosomes during mitosis. Ki-67 is used as a marker for determining the growth fraction of a given population of cells. In studies of tumor cells, the "Ki-67 labeling index" refers to the number of Ki-67 positive cells within the population and this is used to predict outcome of particular cancer types. Ki-67 has been shown to interact with the DNA-bound protein chromobox protein homolog 3 (CBX3) (heterochromatin).

The SolA15 antibody also recognizes human, non-human primate and canine Ki-67.

Applications Reported: This SolA15 antibody has been reported for use in intracellular staining followed by flow cytometric analysis, immunohistochemical staining, and immunocytochemistry.

Applications Tested: This SolA15 antibody has been tested by immunocytochemistry on fixed and permeabilized OLN93 cells at less than or equal to 10 µg/mL. It has also been tested by intracellular staining and flow cytometric analysis of stimulated mouse splenocytes using the Foxp3/Transcription Factor Staining Buffer Set (Product # 00-5523-00) and protocol. For flow application this can be used at less than or equal to 0.25 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.

Excitation: 488 nm; Emission: 520 nm; Laser: Blue Laser.

Filtration: 0.2 µm post-manufacturing filtered.

Target Information

Ki-67 is a nuclear protein that is expressed during various stages in the cell cycle, particularly during late G1, S, G2, and M phases. The protein has a forkhead associated domain (FHA) through which it associates with euchromatin at the perichromosomal layer, the centromeric heterochromatin, and the nucleolus. Ki-67 is shown to have a cell cycle dependent topographical distribution with perinucleolar expression at G1, expression in the nuclear matrix at G2, and expression on the chromosomes during M phase. Ki-67 is commonly used as a proliferation marker because it is not detected in G0 cells, but increases steadily from G1 through mitosis. Ki-67 antibodies are useful in establishing the cell growing fraction in neoplasms. In neoplastic tissues, the prognostic value is comparable to the tritiated thymidine-labelling index. The correlation between low Ki-67 index and histologically low-grade tumors is strong. Ki-67 is routinely used as a neuronal marker of cell cycling and proliferation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

How to use the Panel Builder

Watch the video to learn how to use the Invitrogen Flow Cytometry Panel Builder to build your next flow cytometry panel in 5 easy steps.

Product References

Poly-L-ornithine blocks the inhibitory effects of fibronectin on oligodendrocyte differentiation and promotes myelin repair.

Neural regeneration research

Xiong YJ,Soomro SH,Huang ZH,Yu PP,Ping J,Fu H

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunocytochemistry

Sat Apr 01 00:00:00 UTC 2023

Transformation of primary murine peritoneal mast cells by constitutive KIT activation is accompanied by loss of Cdkn2a/Arf expression.

Frontiers in immunology

Capellmann S,Sonntag R,Schüler H,Meurer SK,Gan L,Kauffmann M,Horn K,Königs-Werner H,Weiskirchen R,Liedtke C,Huber M

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Flow Cytometry

Wed Apr 19 00:00:00 UTC 2023

Extracellular matrix bioink boosts stemness and facilitates transplantation of intestinal organoids as a biosafe Matrigel alternative.

Bioengineering & translational medicine

Xu ZY,Huang JJ,Liu Y,Chen CW,Qu GW,Wang GF,Zhao Y,Wu XW,Ren JA

11-5698-82 was used in Immunocytochemistry-immunofluorescence to show that the development of such photo-responsive bioink has the potential to replace tumor-derived Matrigel and facilitate the application of organoids in translational medicine and disease modeling.

Sun Jan 01 00:00:00 UTC 2023

Mesenchyme-derived vertebrate lonesome kinase controls lung organogenesis by altering the matrisome.

Cellular and molecular life sciences : CMLS

Brütsch SM,Madzharova E,Pantasis S,Wüstemann T,Gurri S,Steenbock H,Gazdhar A,Kuhn G,Angel P,Bellusci S,Brinckmann J,Auf dem Keller U,Werner S,Bordoli MR

11-5698-82 was used in Immunohistochemistry-immunofluorescence to support a role for mesenchyme-derived VLK in lung development through regulation of matrix dynamics and the resulting modulation of alveolar epithelial cell differentiation.

Wed Mar 15 00:00:00 UTC 2023

B-cell antigen receptor expression and phosphatidylinositol 3-kinase signaling regulate genesis and maintenance of mouse chronic lymphocytic leukemia.

Haematologica

Schmid VK,Khadour A,Ahmed N,Brandl C,Nitschke L,Rajewsky K,Jumaa H,Hobeika E

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Flow Cytometry

Mon Aug 01 00:00:00 UTC 2022

Association of Myeloid Liver Kinase B1 Depletion With a Reduction in Alveolar Macrophage Numbers and an Impaired Host Defense During Gram-Negative Pneumonia.

The Journal of infectious diseases

Otto NA,de Vos AF,van Heijst JWJ,Roelofs JJTH,van der Poll T

11-5698 was used in Flow cytometry/Cell sorting to suggest that Myeloid LKB1 is important for local host defense during Klebsiella pneumonia by maintaining adequate AM numbers in the lung.

Fri Apr 01 00:00:00 UTC 2022

Inhibition of LncRNA Vof-16 expression promotes nerve regeneration and functional recovery after spinal cord injury.

Neural regeneration research

Zhang XM,Zeng LN,Yang WY,Ding L,Chen KZ,Fu WJ,Zeng SQ,Liang YR,Chen GH,Wu HF

11-5698-82 was used in Immunocytochemistry-immunofluorescence to suggest that lncRNA Vof-16 is associated with the regulation of inflammation and apoptosis.

Sat Jan 01 00:00:00 UTC 2022

Inhibition of LncRNA Vof-16 expression promotes nerve regeneration and functional recovery after spinal cord injury.

Neural regeneration research

Zhang XM,Zeng LN,Yang WY,Ding L,Chen KZ,Fu WJ,Zeng SQ,Liang YR,Chen GH,Wu HF

11-5698-82 was used in Immunocytochemistry-immunofluorescence to suggest that lncRNA Vof-16 is associated with the regulation of inflammation and apoptosis.

Sat Jan 01 00:00:00 UTC 2022

Bisphenol-A impairs synaptic formation and function by RGS4-mediated regulation of BDNF signaling in the cerebral cortex.

Disease models & mechanisms

Hyun SA,Ko MY,Jang S,Lee BS,Rho J,Kim KK,Kim WY,Ka M

11-5698-82 was used in Immunohistochemistry to provide molecular mechanistic insights into anatomical and physiological neurotoxic consequences related to a potent endocrine modifier.

Fri Jul 01 00:00:00 UTC 2022

Application of an instructive hydrogel accelerates re-epithelialization of xenografted human skin wounds.

Scientific reports

Sparks HD,Mandla S,Vizely K,Rosin N,Radisic M,Biernaskie J

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunohistochemistry

Sat Aug 20 00:00:00 UTC 2022

Application of an instructive hydrogel accelerates re-epithelialization of xenografted human skin wounds.

Scientific reports

Sparks HD,Mandla S,Vizely K,Rosin N,Radisic M,Biernaskie J

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunohistochemistry

Sat Aug 20 00:00:00 UTC 2022

IFN-γ-dependent tumor-antigen cross-presentation by lymphatic endothelial cells promotes their killing by T cells and inhibits metastasis.

Science advances

Garnier L,Pick R,Montorfani J,Sun M,Brighouse D,Liaudet N,Kammertoens T,Blankenstein T,Page N,Bernier-Latamani J,Tran NL,Petrova TV,Merkler D,Scheiermann C,Hugues S

11-5698-82 was used in Flow cytometry/Cell sorting to assess the impact of cytotoxic T cells on the local lymphatic vasculature and concomitant tumor dissemination during an antitumor response.

Fri Jun 10 00:00:00 UTC 2022

Inhibiting Type I Arginine Methyltransferase Activity Promotes T Cell-Mediated Antitumor Immune Responses.

Cancer immunology research

Fedoriw A,Shi L,O'Brien S,Smitheman KN,Wang Y,Hou J,Sherk C,Rajapurkar S,Laraio J,Williams LJ,Xu C,Han G,Feng Q,Bedford MT,Wang L,Barbash O,Kruger RG,Hwu P,Mohammad HP,Peng W

11-5698-82 was used in Flow cytometry/Cell sorting to indicate that type I PRMT inhibition exhibits immunomodulatory properties and synergizes with immune checkpoint blockade to induce durable antitumor responses in a T cell-dependent manner, suggesting that type I PRMT inhibition can potentiate an antitumor immunity in refractory settings.

Fri Apr 01 00:00:00 UTC 2022

Fluorinated triphenylphosphonium analogs improve cell selectivity and in vivo detection of mito-metformin.

iScience

AbuEid M,Keyes RF,McAllister D,Peterson F,Kadamberi IP,Sprague DJ,Chaluvally-Raghavan P,Smith BC,Dwinell MB

11-5698-82 was used in Immunocytochemistry-immunofluorescence to investigate the biological effects of direct modification to TPP+ to improve the efficacy and detection of mito-metformin (MMe), a TPP+-conjugated probe we have shown to have promising preclinical efficacy against solid cancer cells.

Thu Dec 22 00:00:00 UTC 2022

B-cell response to seasonal influenza vaccine in mice is amenable to pharmacological modulation through β-adrenoceptor.

Life sciences

Bufan B,Arsenović-Ranin N,Živković I,Petrović R,Leposavić G

11-5698-82 was used in Flow cytometry/Cell sorting to indicate that chronic propranolol treatment may impair response to QIV.

Fri Jul 15 00:00:00 UTC 2022

Holistic Characterization of Tumor Monocyte-to-Macrophage Differentiation Integrates Distinct Immune Phenotypes in Kidney Cancer.

Cancer immunology research

Mujal AM,Combes AJ,Rao AA,Binnewies M,Samad B,Tsui J,Boissonnas A,Pollack JL,Argüello RJ,Meng MV,Porten SP,Ruhland MK,Barry KC,Chan V,Krummel MF

11-5698-82 was used in Flow cytometry/Cell sorting to show that holistic analysis of monocyte-to-macrophage differentiation creates a framework for critically different immune states.

Fri Apr 01 00:00:00 UTC 2022

GCN2 inhibition sensitizes arginine-deprived hepatocellular carcinoma cells to senolytic treatment.

Cell metabolism

Missiaen R,Anderson NM,Kim LC,Nance B,Burrows M,Skuli N,Carens M,Riscal R,Steensels A,Li F,Simon MC

11-5698-82 was used in Flow Cytometry to suggest novel strategies to treat human liver cancers through targeting SLC7A1 and/or a combination of arginine restriction, inhibition of GCN2, and senolytic agents.

Tue Aug 02 00:00:00 UTC 2022

Therapeutic inhibition of the SRC-kinase HCK facilitates T cell tumor infiltration and improves response to immunotherapy.

Science advances

Poh AR,Love CG,Chisanga D,Steer JH,Baloyan D,Chopin M,Nutt S,Rautela J,Huntington ND,Etemadi N,O'Brien M,O'Keefe R,Ellies LG,Macri C,Mintern JD,Whitehead L,Gangadhara G,Boon L,Chand AL,Lowell CA,Shi W,Pixley FJ,Ernst M

11-5698-82 was used in Flow cytometry/Cell sorting to suggest that therapeutic targeting of HCK activity enhances response to immunotherapy by simultaneously stimulating immune cell activation and inhibiting the immunosuppressive tumor microenvironment.

Fri Jun 24 00:00:00 UTC 2022

FOXP3 exon 2 controls T_reg stability and autoimmunity.

Science immunology

Du J,Wang Q,Yang S,Chen S,Fu Y,Spath S,Domeier P,Hagin D,Anover-Sombke S,Haouili M,Liu S,Wan J,Han L,Liu J,Yang L,Sangani N,Li Y,Lu X,Janga SC,Kaplan MH,Torgerson TR,Ziegler SF,Zhou B

11-5698-82 was used in Flow cytometry/Cell sorting to show that patients expressing only the shorter isoform fail to maintain self-tolerance and develop immunodeficiency, polyendocrinopathy, and enteropathy X-linked (IPEX) syndrome.

Fri Jun 24 00:00:00 UTC 2022

Uncoupling of macrophage inflammation from self-renewal modulates host recovery from respiratory viral infection.

Immunity

Zhu B,Wu Y,Huang S,Zhang R,Son YM,Li C,Cheon IS,Gao X,Wang M,Chen Y,Zhou X,Nguyen Q,Phan AT,Behl S,Taketo MM,Mack M,Shapiro VS,Zeng H,Ebihara H,Mullon JJ,Edell ES,Reisenauer JS,Demirel N,Kern RM,Chakraborty R,Cui W,Kaplan MH,Zhou X,Goldrath AW,Sun J

11-5698-82 was used in Flow cytometry/Cell sorting to examine the relationship between proliferative and inflammatory properties of tissue macrophages by defining the impact of the Wnt/β-catenin pathway in alveolar macrophages.

Tue Jun 08 00:00:00 UTC 2021

Visualization of individual cell division history in complex tissues using iCOUNT.

Cell stem cell

Denoth-Lippuner A,Jaeger BN,Liang T,Royall LN,Chie SE,Buthey K,Machado D,Korobeynyk VI,Kruse M,Munz CM,Gerbaulet A,Simons BD,Jessberger S

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunocytochemistry

Thu Nov 04 00:00:00 UTC 2021

Epicardial placement of human MSC-loaded fibrin sealant films for heart failure: Preclinical efficacy and mechanistic data.

Molecular therapy : the journal of the American Society of Gene Therapy

Fields L,Ito T,Kobayashi K,Ichihara Y,Podaru MN,Hussain M,Yamashita K,Machado V,Lewis-McDougall F,Suzuki K

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunocytochemistry

Wed Aug 04 00:00:00 UTC 2021

Ageing promotes early T follicular helper cell differentiation by modulating expression of RBPJ.

Aging cell

Webb LMC,Fra-Bido S,Innocentin S,Matheson LS,Attaf N,Bignon A,Novarino J,Fazilleau N,Linterman MA

11-5698-82 was used in Flow Cytometry to show increased formation of Tfh precursors (pre-Tfh) but no associated increase in germinal centre (GC)-Tfh cells in aged mice, suggesting age-driven promotion of only early Tfh cell differentiation.

Fri Jan 01 00:00:00 UTC 2021

Heterogeneity of astrocytes: Electrophysiological properties of juxtavascular astrocytes before and after brain injury.

Glia

Götz S,Bribian A,López-Mascaraque L,Götz M,Grothe B,Kunz L

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunocytochemistry

Mon Feb 01 00:00:00 UTC 2021

Environmental oxygen regulates astrocyte proliferation to guide angiogenesis during retinal development.

Development (Cambridge, England)

Perelli RM,O'Sullivan ML,Zarnick S,Kay JN

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunohistochemistry

Sat May 01 00:00:00 UTC 2021

Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition).

European journal of immunology

Cossarizza A,Chang HD,Radbruch A,Abrignani S,Addo R,Akdis M,Andrä I,Andreata F,Annunziato F,Arranz E,Bacher P,Bari S,Barnaba V,Barros-Martins J,Baumjohann D,Beccaria CG,Bernardo D,Boardman DA,Borger J,Böttcher C,Brockmann L,Burns M,Busch DH,Cameron G,Cammarata I,Cassotta A,Chang Y,Chirdo FG,Christakou E,Čičin-Šain L,Cook L,Corbett AJ,Cornelis R,Cosmi L,Davey MS,De Biasi S,De Simone G,Del Zotto G,Delacher M,Di Rosa F,Di Santo J,Diefenbach A,Dong J,Dörner T,Dress RJ,Dutertre CA,Eckle SBG,Eede P,Evrard M,Falk CS,Feuerer M,Fillatreau S,Fiz-Lopez A,Follo M,Foulds GA,Fröbel J,Gagliani N,Galletti G,Gangaev A,Garbi N,Garrote JA,Geginat J,Gherardin NA,Gibellini L,Ginhoux F,Godfrey DI,Gruarin P,Haftmann C,Hansmann L,Harpur CM,Hayday AC,Heine G,Hernández DC,Herrmann M,Hoelsken O,Huang Q,Huber S,Huber JE,Huehn J,Hundemer M,Hwang WYK,Iannacone M,Ivison SM,Jäck HM,Jani PK,Keller B,Kessler N,Ketelaars S,Knop L,Knopf J,Koay HF,Kobow K,Kriegsmann K,Kristyanto H,Krueger A,Kuehne JF,Kunze-Schumacher H,Kvistborg P,Kwok I,Latorre D,Lenz D,Levings MK,Lino AC,Liotta F,Long HM,Lugli E,MacDonald KN,Maggi L,Maini MK,Mair F,Manta C,Manz RA,Mashreghi MF,Mazzoni A,McCluskey J,Mei HE,Melchers F,Melzer S,Mielenz D,Monin L,Moretta L,Multhoff G,Muñoz LE,Muñoz-Ruiz M,Muscate F,Natalini A,Neumann K,Ng LG,Niedobitek A,Niemz J,Almeida LN,Notarbartolo S,Ostendorf L,Pallett LJ,Patel AA,Percin GI,Peruzzi G,Pinti M,Pockley AG,Pracht K,Prinz I,Pujol-Autonell I,Pulvirenti N,Quatrini L,Quinn KM,Radbruch H,Rhys H,Rodrigo MB,Romagnani C,Saggau C,Sakaguchi S,Sallusto F,Sanderink L,Sandrock I,Schauer C,Scheffold A,Scherer HU,Schiemann M,Schildberg FA,Schober K,Schoen J,Schuh W,Schüler T,Schulz AR,Schulz S,Schulze J,Simonetti S,Singh J,Sitnik KM,Stark R,Starossom S,Stehle C,Szelinski F,Tan L,Tarnok A,Tornack J,Tree TIM,van Beek JJP,van de Veen W,van Gisbergen K,Vasco C,Verheyden NA,von Borstel A,Ward-Hartstonge KA,Warnatz K,Waskow C,Wiedemann A,Wilharm A,Wing J,Wirz O,Wittner J,Yang JHM,Yang J

11-5698-82 was used in Miscellaneous to provide the key aspects to consider when performing flow cytometry experiments.

Wed Dec 01 00:00:00 UTC 2021

HDAC1 Regulates Neuronal Differentiation.

Frontiers in molecular neuroscience

Nieto-Estevez V,Changarathil G,Adeyeye AO,Coppin MO,Kassim RS,Zhu J,Hsieh J

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunohistochemistry (PFA fixed)

Tue Feb 01 00:00:00 UTC 2022

Macrophage LAMTOR1 Deficiency Prevents Dietary Obesity and Insulin Resistance Through Inflammation-Induced Energy Expenditure.

Frontiers in cell and developmental biology

Ying L,Zhang M,Ma X,Si Y,Li X,Su J,Yin J,Bao Y

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Flow Cytometry

Tue Jun 08 00:00:00 UTC 2021

Transcription factor old astrocyte specifically induced substance is a novel regulator of kidney fibrosis.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Yamamoto A,Morioki H,Nakae T,Miyake Y,Harada T,Noda S,Mitsuoka S,Matsumoto K,Tomimatsu M,Kanemoto S,Tanaka S,Maeda M,Conway SJ,Imaizumi K,Fujio Y,Obana M

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunohistochemistry

Mon Feb 01 00:00:00 UTC 2021

HOXA11 plays critical roles in disease progression and response to cytarabine in AML.

Oncology reports

Fu JF,Shih LY,Yen TH

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Flow Cytometry

Thu Jul 01 00:00:00 UTC 2021

Thrombospondin-2 spatiotemporal expression in skeletal fractures.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society

Zondervan RL,Jenkins DC,Reicha JD,Hankenson KD

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunocytochemistry

Fri Jan 01 00:00:00 UTC 2021

MicroRNA-384 inhibits nasopharyngeal carcinoma growth and metastasis via binding to Smad5 and suppressing the Wnt/β-catenin axis.

Cytotechnology

Zeng X,Liao H,Wang F

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunohistochemistry

Thu Apr 01 00:00:00 UTC 2021

IL-1beta promotes the age-associated decline of beta cell function.

iScience

Böni-Schnetzler M,Méreau H,Rachid L,Wiedemann SJ,Schulze F,Trimigliozzi K,Meier DT,Donath MY

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunohistochemistry

Fri Nov 19 00:00:00 UTC 2021

Adult neural stem cells have latent inflammatory potential that is kept suppressed by Tcf4 to facilitate adult neurogenesis.

Science advances

Shariq M,Sahasrabuddhe V,Krishna S,Radha S,Bellampalli R,Dwivedi A,Cheramangalam R,Reizis B,Hébert J,Ghosh HS

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunohistochemistry

Sat May 01 00:00:00 UTC 2021

A booster dose enhances immunogenicity of the COVID-19 vaccine candidate ChAdOx1 nCoV-19 in aged mice.

Med (New York, N.Y.)

Silva-Cayetano A,Foster WS,Innocentin S,Belij-Rammerstorfer S,Spencer AJ,Burton OT,Fra-Bidó S,Le Lee J,Thakur N,Conceicao C,Wright D,Barrett J,Evans-Bailey N,Noble C,Bailey D,Liston A,Gilbert SC,Lambe T,Linterman MA

11-5698-82 was used in Flow Cytometry, Immunohistochemistry to show that ChAdOx1 nCoV-19 induces both cellular and humoral immunity in adult and aged mice and suggest a prime-boost strategy is a rational approach to enhance immunogenicity in older persons.

Fri Mar 12 00:00:00 UTC 2021

A booster dose enhances immunogenicity of the COVID-19 vaccine candidate ChAdOx1 nCoV-19 in aged mice.

Med (New York, N.Y.)

Fri Mar 12 00:00:00 UTC 2021

Targeting Feedforward Loops Formed by Nuclear Receptor RORγ and Kinase PBK in mCRPC with Hyperactive AR Signaling.

Cancers

Zhang X,Huang Z,Wang J,Ma Z,Yang J,Corey E,Evans CP,Yu AM,Chen HW

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunohistochemistry

Thu Apr 01 00:00:00 UTC 2021

Requirement of DNMT1 to orchestrate epigenomic reprogramming for NPM-ALK-driven lymphomagenesis.

Life science alliance

Redl E,Sheibani-Tezerji R,Cardona CJ,Hamminger P,Timelthaler G,Hassler MR,Zrimšek M,Lagger S,Dillinger T,Hofbauer L,Draganić K,Tiefenbacher A,Kothmayer M,Dietz CH,Ramsahoye BH,Kenner L,Bock C,Seiser C,Ellmeier W,Schweikert G,Egger G

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunohistochemistry

Mon Feb 01 00:00:00 UTC 2021

Notch Signaling between Cerebellar Granule Cell Progenitors.

eNeuro

Adachi T,Miyashita S,Yamashita M,Shimoda M,Okonechnikov K,Chavez L,Kool M,Pfister SM,Inoue T,Kawauchi D,Hoshino M

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunohistochemistry

Fri Jul 02 00:00:00 UTC 2021

Dissecting phenotypic transitions in metastatic disease via photoconversion-based isolation.

eLife

Sela Y,Li J,Kuri P,Merrell AJ,Li N,Lengner C,Rompolas P,Stanger BZ

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunohistochemistry

Tue Feb 23 00:00:00 UTC 2021

Cell death & disease

Catlin JP,Marziali LN,Rein B,Yan Z,Feltri ML,Schaner Tooley CE

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunocytochemistry

Thu Oct 28 00:00:00 UTC 2021

Delta-like 4 is required for pulmonary vascular arborization and alveolarization in the developing lung.

JCI insight

Xia S,Menden HL,Townley N,Mabry SM,Johnston J,Nyp MF,Heruth DP,Korfhagen T,Sampath V

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunohistochemistry

Thu Apr 08 00:00:00 UTC 2021

Shikonin Derivatives from Onsoma visianii Decrease Expression of Phosphorylated STAT3 in Leukemia Cells and Exert Antitumor Activity.

Nutrients

Todorovic Z,Milovanovic J,Arsenijevic D,Vukovic N,Vukic M,Arsenijevic A,Djurdjevic P,Milovanovic M,Arsenijevic N

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Flow Cytometry

Wed Mar 31 00:00:00 UTC 2021

CDCP1 promotes compensatory renal growth by integrating Src and Met signaling.

Life science alliance

Kajiwara K,Yamano S,Aoki K,Okuzaki D,Matsumoto K,Okada M

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunohistochemistry

Thu Apr 01 00:00:00 UTC 2021

Targeting Phosphatidylserine Enhances the Anti-tumor Response to Tumor-Directed Radiation Therapy in a Preclinical Model of Melanoma.

Cell reports

Budhu S,Giese R,Gupta A,Fitzgerald K,Zappasodi R,Schad S,Hirschhorn D,Campesato LF,De Henau O,Gigoux M,Liu C,Mazo G,Deng L,Barker CA,Wolchok JD,Merghoub T

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Flow Cytometry

Tue Jan 12 00:00:00 UTC 2021

GTSE1 is possibly involved in the DNA damage repair and cisplatin resistance in osteosarcoma.

Journal of orthopaedic surgery and research

Xie C,Xiang W,Shen H,Shen J

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunohistochemistry

Tue Dec 07 00:00:00 UTC 2021

An mTORC1-dependent switch orchestrates the transition between mouse spermatogonial stem cells and clones of progenitor spermatogonia.

Cell reports

Suzuki S,McCarrey JR,Hermann BP

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Flow Cytometry

Tue Feb 16 00:00:00 UTC 2021

An mTORC1-dependent switch orchestrates the transition between mouse spermatogonial stem cells and clones of progenitor spermatogonia.

Cell reports

Suzuki S,McCarrey JR,Hermann BP

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Flow Cytometry

Tue Feb 16 00:00:00 UTC 2021

TWIK-1 BAC-GFP Transgenic Mice, an Animal Model for TWIK-1 Expression.

Cells

Kwon O,Yang H,Kim SC,Kim J,Sim J,Lee J,Hwang EM,Shim S,Park JY

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunohistochemistry

Thu Oct 14 00:00:00 UTC 2021

Ten-eleven translocation protein 1 modulates medulloblastoma progression.

Genome biology

Kim H,Kang Y,Li Y,Chen L,Lin L,Johnson ND,Zhu D,Robinson MH,McSwain L,Barwick BG,Yuan X,Liao X,Zhao J,Zhang Z,Shu Q,Chen J,Allen EG,Kenney AM,Castellino RC,Van Meir EG,Conneely KN,Vertino PM,Jin P,Li J

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunohistochemistry

Thu Apr 29 00:00:00 UTC 2021

Field size effects on DNA damage and proliferation in normal human cell populations irradiated with X-ray microbeams.

Scientific reports

Ojima M,Ito A,Usami N,Ohara M,Suzuki K,Kai M

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunocytochemistry

Fri Mar 26 00:00:00 UTC 2021

CXCR4 Regulates Temporal Differentiation via PRC1 Complex in Organogenesis of Epithelial Glands.

International journal of molecular sciences

Kim J,Lee SW,Park K

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunocytochemistry

Sun Jan 10 00:00:00 UTC 2021

Mutant ASXL1 induces age-related expansion of phenotypic hematopoietic stem cells through activation of Akt/mTOR pathway.

Nature communications

Fujino T,Goyama S,Sugiura Y,Inoue D,Asada S,Yamasaki S,Matsumoto A,Yamaguchi K,Isobe Y,Tsuchiya A,Shikata S,Sato N,Morinaga H,Fukuyama T,Tanaka Y,Fukushima T,Takeda R,Yamamoto K,Honda H,Nishimura EK,Furukawa Y,Shibata T,Abdel-Wahab O,Suematsu M,Kitamura T

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Flow Cytometry

Tue Mar 23 00:00:00 UTC 2021

Gene Signatures Detect Damaged Liver Sinusoidal Endothelial Cells in Chronic Liver Diseases.

Frontiers in medicine

Verhulst S,van Os EA,De Smet V,Eysackers N,Mannaerts I,van Grunsven LA

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunocytochemistry

Wed Nov 10 00:00:00 UTC 2021

Imbalanced Activation of Wnt-/β-Catenin-Signaling in Liver Endothelium Alters Normal Sinusoidal Differentiation.

Frontiers in physiology

Koch PS,Sandorski K,Heil J,Schmid CD,Kürschner SW,Hoffmann J,Winkler M,Staniczek T,de la Torre C,Sticht C,Schledzewski K,Taketo MM,Trogisch FA,Heineke J,Géraud C,Goerdt S,Olsavszky V

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunohistochemistry

Fri Oct 22 00:00:00 UTC 2021

NEIL3-deficiency increases gut permeability and contributes to a pro-atherogenic metabolic phenotype.

Scientific reports

Karlsen TR,Kong XY,Holm S,Quiles-Jiménez A,Dahl TB,Yang K,Sagen EL,Skarpengland T,S Øgaard JD,Holm K,Vestad B,Olsen MB,Aukrust P,Bjørås M,Hov JR,Halvorsen B,Gregersen I

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunocytochemistry

Tue Oct 05 00:00:00 UTC 2021

Developmental Role of Adenosine Kinase in the Cerebellum.

eNeuro

Gebril H,Wahba A,Zhou X,Lai T,Alharfoush E,DiCicco-Bloom E,Boison D

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunohistochemistry

Fri Jul 02 00:00:00 UTC 2021

A defined subset of clonal retinal stem cell spheres is biased to RPE differentiation.

iScience

Baakdhah TW,Coles B,van der Kooy D

11-5698-82 was used in Flow Cytometry to conclude that HP and LP spheres contain late RPE progenitors which are not affected by proliferative signals.

Fri Jun 25 00:00:00 UTC 2021

Intestinal CD11b⁺ B Cells Ameliorate Colitis by Secreting Immunoglobulin A.

Frontiers in immunology

Fu Y,Wang Z,Yu B,Lin Y,Huang E,Liu R,Zhao C,Lu M,Xu W,Liu H,Liu Y,Wang L,Chu Y

11-5698-82 was used in Flow Cytometry to demonstrate that CD11b+ B cells are essential intestinal suppressive immune cells and the primary source of intestinal IgA, which plays an indispensable role in maintaining intestinal homeostasis.

Fri Jan 07 00:00:00 UTC 2022

Aptamer-assisted tumor localization of bacteria for enhanced biotherapy.

Nature communications

Geng Z,Cao Z,Liu R,Liu K,Liu J,Tan W

11-5698-82 was used in Flow Cytometry to demonstrate how bacterial behaviors can be tuned by surface conjugation and supports the potential of aptamer-conjugated bacteria for both targeted intratumoral localization and enhanced tumor biotherapy.

Mon Nov 15 00:00:00 UTC 2021

Combined OX40 Agonist and PD-1 Inhibitor Immunotherapy Improves the Efficacy of Vascular Targeted Photodynamic Therapy in a Urothelial Tumor Model.

Molecules (Basel, Switzerland)

Alvim RG,Georgala P,Nogueira L,Somma AJ,Nagar K,Thomas J,Alvim L,Riegel A,Hughes C,Chen J,Reis AB,Lebdai S,Scherz A,Zanganeh S,Gardner R,Kim K,Coleman JA

11-5698-82 was used in Flow Cytometry to study the efficacy of the vascular targeted photodynamic therapy in combination with concurrent PD-1 inhibitor/OX40 agonist immunotherapy in a urothelial tumor-bearing model.

Sat Jun 19 00:00:00 UTC 2021

Disruption of Tfh:B Cell Interactions Prevents Antibody-Mediated Rejection in a Kidney Transplant Model in Rats: Impact of Calcineurin Inhibitor Dose.

Frontiers in immunology

Steines L,Poth H,Schuster A,Amann K,Banas B,Bergler T

11-5698-82 was used in Immunocytochemistry to conclude that Tfh:B cell crosstalk was controlled only by hiCNI treatment, preventing the development of DSA and ABMR.

Tue Sep 28 00:00:00 UTC 2021

Cell-Intrinsic Tumorigenic Functions of PPARγ in Bladder Urothelial Carcinoma.

Molecular cancer research : MCR

Sanchez DJ,Missiaen R,Skuli N,Steger DJ,Simon MC

11-5698-82 was used in Flow cytometry/Cell sorting to indicate that PPARγ promotes UC progression in a subset of patients, at least in part, through cell-autonomous mechanisms linked to SHH signaling.

Thu Apr 01 00:00:00 UTC 2021

An in vivo model allowing continuous observation of human vascular formation in the same animal over time.

Scientific reports

Tsukada Y,Muramatsu F,Hayashi Y,Inagaki C,Su H,Iba T,Kidoya H,Takakura N

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunohistochemistry

Tue Jan 12 00:00:00 UTC 2021

Assaying Cell Cycle Status Using Flow Cytometry.

Methods in molecular biology (Clifton, N.J.)

Rahmé R

11-5698-82 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry to describe methods to assess cell cycle status in flow cytometry.

Wed Jun 16 00:00:00 UTC 2021

Inhibition of glycolysis in the presence of antigen generates suppressive antigen-specific responses and restrains rheumatoid arthritis in mice.

Biomaterials

Mangal JL,Inamdar S,Le T,Shi X,Curtis M,Gu H,Acharya AP

11-5698-82 was used in Flow Cytometry to investigate the metabolic reprogramming of Dendritic cells (DC), in the presence of an antigen, generates anti-inflammatory DC and T cell responses for the treatment of arthritis symptoms in collagen-induced autoimmune arthritis mice.

Fri Oct 01 00:00:00 UTC 2021

EBF1-deficient bone marrow stroma elicits persistent changes in HSC potential.

Nature immunology

Derecka M,Herman JS,Cauchy P,Ramamoorthy S,Lupar E,Grün D,Grosschedl R

11-5698-82 was used in Flow Cytometry to investigate how transcriptional changes in bone marrow (BM) mesenchymal stromal cells result in long-lasting effects on hematopoietic stem cells.

Sun Mar 01 00:00:00 UTC 2020

Human Lung Stem Cell-Based Alveolospheres Provide Insights into SARS-CoV-2-Mediated Interferon Responses and Pneumocyte Dysfunction.

Cell stem cell

Katsura H,Sontake V,Tata A,Kobayashi Y,Edwards CE,Heaton BE,Konkimalla A,Asakura T,Mikami Y,Fritch EJ,Lee PJ,Heaton NS,Boucher RC,Randell SH,Baric RS,Tata PR

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunocytochemistry

Thu Dec 03 00:00:00 UTC 2020

Egr2-guided histone H2B monoubiquitination is required for peripheral nervous system myelination.

Nucleic acids research

Wüst HM,Wegener A,Fröb F,Hartwig AC,Wegwitz F,Kari V,Schimmel M,Tamm ER,Johnsen SA,Wegner M,Sock E

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunocytochemistry

Fri Sep 18 00:00:00 UTC 2020

Genetic manipulation of LKB1 elicits lethal metastatic prostate cancer.

The Journal of experimental medicine

Hermanova I,Zúñiga-García P,Caro-Maldonado A,Fernandez-Ruiz S,Salvador F,Martín-Martín N,Zabala-Letona A,Nuñez-Olle M,Torrano V,Camacho L,Lizcano JM,Talamillo A,Carreira S,Gurel B,Cortazar AR,Guiu M,López JI,Martinez-Romero A,Astobiza I,Valcarcel-Jimenez L,Lorente M,Arruabarrena-Aristorena A,Velasco G,Gomez-Muñoz A,Suárez-Cabrera C,Lodewijk I,Flores JM,Sutherland JD,Barrio R,de Bono JS,Paramio JM,Trka J,Graupera M,Gomis RR,Carracedo A

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunohistochemistry

Mon Jun 01 00:00:00 UTC 2020

Epithelial Vegfa Specifies a Distinct Endothelial Population in the Mouse Lung.

Developmental cell

Vila Ellis L,Cain MP,Hutchison V,Flodby P,Crandall ED,Borok Z,Zhou B,Ostrin EJ,Wythe JD,Chen J

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunocytochemistry

Mon Mar 09 00:00:00 UTC 2020

Multimodal single-cell analysis reveals distinct radioresistant stem-like and progenitor cell populations in murine glioma.

Glia

Alexander J,LaPlant QC,Pattwell SS,Szulzewsky F,Cimino PJ,Caruso FP,Pugliese P,Chen Z,Chardon F,Hill AJ,Spurrell C,Ahrendsen D,Pietras A,Starita LM,Hambardzumyan D,Iavarone A,Shendure J,Holland EC

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunohistochemistry

Tue Dec 01 00:00:00 UTC 2020

Metabolite releasing polymers control dendritic cell function by modulating their energy metabolism.

Journal of materials chemistry. B

Mangal JL,Inamdar S,Yang Y,Dutta S,Wankhede M,Shi X,Gu H,Green M,Rege K,Curtis M,Acharya AP

11-5698-82 was used in Flow Cytometry to investigate if intracellular delivery of key-metabolites in a sustained manner provides a new direction in immunometabolism field-based immunotherapy with potential applications in different diseases associated with immune disorders.

Wed Jun 24 00:00:00 UTC 2020

FGF2 modulates simultaneously the mode, the rate of division and the growth fraction in cultures of radial glia.

Development (Cambridge, England)

Ledesma-Terrón M,Peralta-Cañadas N,Míguez DG

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunocytochemistry

Fri Jul 24 00:00:00 UTC 2020

NPC1 deficiency impairs cerebellar postnatal development of microglia and climbing fiber refinement in a mouse model of Niemann-Pick disease type C.

Development (Cambridge, England)

Boyle BR,Melli SE,Altreche RS,Padron ZM,Yousufzai FAK,Kim S,Vasquez MD,Carone DM,Carone BR,Soto I

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunohistochemistry (Frozen)

Mon Aug 03 00:00:00 UTC 2020

Novel enhanced GFP-positive congenic inbred strain establishment and application of tumor-bearing nude mouse model.

Cancer science

Lan Q,Chen Y,Dai C,Li S,Fei X,Dong J,Shen Y,Dai X,Lu Z,Liu B,Wang Q,Wang H,Zhou Z,Ji X,Wang Z,Huang Q

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunocytochemistry

Thu Oct 01 00:00:00 UTC 2020

Mycobacterium tuberculosis-infected alveolar epithelial cells modulate dendritic cell function through the HIF-1α-NOS2 axis.

Journal of leukocyte biology

Rodrigues TS,Alvarez ARP,Gembre AF,Forni MFPAD,de Melo BMS,Alves Filho JCF,Câmara NOS,Bonato VLD

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Flow Cytometry

Thu Oct 01 00:00:00 UTC 2020

In vivo antitumor activity by dual stromal and tumor-targeted oncolytic measles viruses.

Cancer gene therapy

Jing Y,Chavez V,Khatwani N,Ban Y,Espejo AP,Chen X,Merchan JR

11-5698 was used in Immunohistochemistry-immunofluorescence to validate the concept that dual stromal and tumor cell viral targeting enhances the therapeutic effects of systemically administered oncolytic viruses.

Tue Dec 01 00:00:00 UTC 2020

Radiation Induced Metabolic Alterations Associate With Tumor Aggressiveness and Poor Outcome in Glioblastoma.

Frontiers in oncology

Gupta K,Vuckovic I,Zhang S,Xiong Y,Carlson BL,Jacobs J,Olson I,Petterson XM,Macura SI,Sarkaria J,Burns TC

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunocytochemistry

Mon Sep 28 00:00:00 UTC 2020

Radiation Induced Metabolic Alterations Associate With Tumor Aggressiveness and Poor Outcome in Glioblastoma.

Frontiers in oncology

Gupta K,Vuckovic I,Zhang S,Xiong Y,Carlson BL,Jacobs J,Olson I,Petterson XM,Macura SI,Sarkaria J,Burns TC

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunocytochemistry

Mon Sep 28 00:00:00 UTC 2020

TNFSF15 facilitates human umbilical cord blood haematopoietic stem cell expansion by activating Notch signal pathway.

Journal of cellular and molecular medicine

Ding Y,Gao S,Shen J,Bai T,Yang M,Xu S,Gao Y,Zhang Z,Li L

11-5698 was used in Flow cytometry/Cell sorting to indicate that TNFSF15 is useful for in vitro expansion of UCB-HSC for clinical applications.

Thu Oct 01 00:00:00 UTC 2020

TNFSF15 facilitates human umbilical cord blood haematopoietic stem cell expansion by activating Notch signal pathway.

Journal of cellular and molecular medicine

Ding Y,Gao S,Shen J,Bai T,Yang M,Xu S,Gao Y,Zhang Z,Li L

11-5698 was used in Flow cytometry/Cell sorting to indicate that TNFSF15 is useful for in vitro expansion of UCB-HSC for clinical applications.

Thu Oct 01 00:00:00 UTC 2020

BMP2 signalling activation enhances bone metastases of non-small cell lung cancer.

Journal of cellular and molecular medicine

Huang F,Cao Y,Wu G,Chen J,Lin W,Lan R,Wu B,Xie X,Hong J,Fu L

11-5698 was used in Flow cytometry/Cell sorting to investigate whether BMP2 contributes to non-small cell lung cancer bone metastasis.

Tue Sep 01 00:00:00 UTC 2020

Agrin Promotes Limbal Stem Cell Proliferation and Corneal Wound Healing Through Hippo-Yap Signaling Pathway.

Investigative ophthalmology & visual science

Hou L,Fu W,Liu Y,Wang Q,Wang L,Huang Y

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunocytochemistry

Mon May 11 00:00:00 UTC 2020

Modeling dermatophytosis: Guinea pig skin explants represent a highly suitable model to study Trichophyton benhamiae infections.

The Journal of dermatology

Baumbach CM,Schrödl W,Nenoff P,Uhrlaß S,Mülling CKW,Michler JK

11-5698-82 was used in Immunohistochemistry to establish an Dermatophyte infection model based on guinea pig skin explants mimicking the in vivo situation as closely as possible to survey the pathogenesis of dermatophytoses.

Wed Jan 01 00:00:00 UTC 2020

Quinazolinone derivative BNUA-3 ameliorated [NDEA+2-AAF]-induced liver carcinogenesis in SD rats by modulating AhR-CYP1B1-Nrf2-Keap1 pathway.

Clinical and experimental pharmacology & physiology

Bose P,Siddique MUM,Acharya R,Jayaprakash V,Sinha BN,Lapenna A,Pattanayak SP

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunohistochemistry

Wed Jan 01 00:00:00 UTC 2020

New Insights into the Pathogenesis of Diabetic Nephropathy: Proximal Renal Tubules Are Primary Target of Oxidative Stress in Diabetic Kidney.

Acta histochemica et cytochemica

Haraguchi R,Kohara Y,Matsubayashi K,Kitazawa R,Kitazawa S

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunohistochemistry

Tue Apr 28 00:00:00 UTC 2020

A discrete subtype of neural progenitor crucial for cortical folding in the gyrencephalic mammalian brain.

eLife

Matsumoto N,Tanaka S,Horiike T,Shinmyo Y,Kawasaki H

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunocytochemistry

Tue Apr 21 00:00:00 UTC 2020

A discrete subtype of neural progenitor crucial for cortical folding in the gyrencephalic mammalian brain.

eLife

Matsumoto N,Tanaka S,Horiike T,Shinmyo Y,Kawasaki H

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunocytochemistry

Tue Apr 21 00:00:00 UTC 2020

Treatment of mice with a ligand binding blocking anti-CD28 monoclonal antibody improves healing after myocardial infarction.

PloS one

Gladow N,Hollmann C,Ramos G,Frantz S,Kerkau T,Beyersdorf N,Hofmann U

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Flow Cytometry

Mon Jul 06 00:00:00 UTC 2020

Adenosine kinase inhibition promotes proliferation of neural stem cells after traumatic brain injury.

Brain communications

Gebril HM,Rose RM,Gesese R,Emond MP,Huo Y,Aronica E,Boison D

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunohistochemistry

Fri Apr 02 00:00:00 UTC 2021

Adenosine kinase inhibition promotes proliferation of neural stem cells after traumatic brain injury.

Brain communications

Gebril HM,Rose RM,Gesese R,Emond MP,Huo Y,Aronica E,Boison D

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunohistochemistry

Fri Apr 02 00:00:00 UTC 2021

Discrete populations of isotype-switched memory B lymphocytes are maintained in murine spleen and bone marrow.

Nature communications

Riedel R,Addo R,Ferreira-Gomes M,Heinz GA,Heinrich F,Kummer J,Greiff V,Schulz D,Klaeden C,Cornelis R,Menzel U,Kröger S,Stervbo U,Köhler R,Haftmann C,Kühnel S,Lehmann K,Maschmeyer P,McGrath M,Naundorf S,Hahne S,Sercan-Alp Ö,Siracusa F,Stefanowski J,Weber M,Westendorf K,Zimmermann J,Hauser AE,Reddy ST,Durek P,Chang HD,Mashreghi MF,Radbruch A

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Flow Cytometry

Fri May 22 00:00:00 UTC 2020

Follicular Regulatory T Cells Can Access the Germinal Center Independently of CXCR5.

Cell reports

Vanderleyden I,Fra-Bido SC,Innocentin S,Stebegg M,Okkenhaug H,Evans-Bailey N,Pierson W,Denton AE,Linterman MA

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunofluorescence

Tue Jan 21 00:00:00 UTC 2020

Follicular Regulatory T Cells Can Access the Germinal Center Independently of CXCR5.

Cell reports

Vanderleyden I,Fra-Bido SC,Innocentin S,Stebegg M,Okkenhaug H,Evans-Bailey N,Pierson W,Denton AE,Linterman MA

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunofluorescence

Tue Jan 21 00:00:00 UTC 2020

Elevated Serum Amino Acids Induce a Subpopulation of Alpha Cells to Initiate Pancreatic Neuroendocrine Tumor Formation.

Cell reports. Medicine

Smith DK,Kates L,Durinck S,Patel N,Stawiski EW,Kljavin N,Foreman O,Sipos B,Solloway MJ,Allan BB,Peterson AS

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunohistochemistry

Tue Aug 25 00:00:00 UTC 2020

A single-cell transcriptomic and anatomic atlas of mouse dorsal raphe Pet1 neurons.

eLife

Okaty BW,Sturrock N,Escobedo Lozoya Y,Chang Y,Senft RA,Lyon KA,Alekseyenko OV,Dymecki SM

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunohistochemistry

Mon Jun 22 00:00:00 UTC 2020

Interleukin-13 disrupts type 2 pneumocyte stem cell activity.

JCI insight

Glisinski KM,Schlobohm AJ,Paramore SV,Birukova A,Moseley MA,Foster MW,Barkauskas CE

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunocytochemistry

Thu Jan 16 00:00:00 UTC 2020

Interleukin-13 disrupts type 2 pneumocyte stem cell activity.

JCI insight

Glisinski KM,Schlobohm AJ,Paramore SV,Birukova A,Moseley MA,Foster MW,Barkauskas CE

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunocytochemistry

Thu Jan 16 00:00:00 UTC 2020

CD103⁺ cDC1 and endogenous CD8⁺ T cells are necessary for improved CD40L-overexpressing CAR T cell antitumor function.

Nature communications

Kuhn NF,Lopez AV,Li X,Cai W,Daniyan AF,Brentjens RJ

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Flow Cytometry

Wed Dec 02 00:00:00 UTC 2020

Chemosensitization of prostate cancer stem cells in mice by angiogenin and plexin-B2 inhibitors.

Communications biology

Li S,Goncalves KA,Lyu B,Yuan L,Hu GF

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Flow Cytometry

Wed Jan 15 00:00:00 UTC 2020

Changes in Liver Mechanical Properties and Water Diffusivity During Normal Pregnancy Are Driven by Cellular Hypertrophy.

Frontiers in physiology

Garczyńska K,Tzschätzsch H,Kühl AA,Morr AS,Lilaj L,Häckel A,Schellenberger E,Berndt N,Holzhütter HG,Braun J,Sack I,Guo J

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunohistochemistry

Fri Dec 18 00:00:00 UTC 2020

Regeneration of the pulmonary vascular endothelium after viral pneumonia requires COUP-TF2.

Science advances

Zhao G,Weiner AI,Neupauer KM,de Mello Costa MF,Palashikar G,Adams-Tzivelekidis S,Mangalmurti NS,Vaughan AE

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunocytochemistry

Sun Nov 01 00:00:00 UTC 2020

Aripiprazole reduces liver cell division.

PloS one

Pirc Marolt T,Kramar B,Bulc Rozman K,Šuput D,Milisav I

11-5698-82 was used in Immunocytochemistry to report that therapeutically relevant aripiprazole concentrations, equal to laboratory alert levels in patients' serum, reduce the rate of hepatocytes' division.

Tue Dec 08 00:00:00 UTC 2020

Aripiprazole reduces liver cell division.

PloS one

Pirc Marolt T,Kramar B,Bulc Rozman K,Šuput D,Milisav I

Tue Dec 08 00:00:00 UTC 2020

Cardiac fibroblast proliferation rates and collagen expression mature early and are unaltered with advancing age.

JCI insight

Wu R,Ma F,Tosevska A,Farrell C,Pellegrini M,Deb A

11-5698 was used in Flow cytometry/Cell sorting to demonstrated that more than 50% of cardiac fibroblasts were actively proliferating in the first day of postnatal life.

Thu Dec 17 00:00:00 UTC 2020

Cardiac fibroblast proliferation rates and collagen expression mature early and are unaltered with advancing age.

JCI insight

Wu R,Ma F,Tosevska A,Farrell C,Pellegrini M,Deb A

11-5698 was used in Flow cytometry/Cell sorting to demonstrated that more than 50% of cardiac fibroblasts were actively proliferating in the first day of postnatal life.

Thu Dec 17 00:00:00 UTC 2020

Comparative Analysis of Age-Related Changes in Lacrimal Glands and Meibomian Glands of a C57BL/6 Male Mouse Model.

International journal of molecular sciences

Yoon CH,Ryu JS,Hwang HS,Kim MK

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunohistochemistry

Thu Jun 11 00:00:00 UTC 2020

Transcriptome analysis of basic fibroblast growth factor treated stem cells isolated from human exfoliated deciduous teeth.

Heliyon

Nowwarote N,Manokawinchoke J,Kanjana K,Fournier BPJ,Sukarawan W,Osathanon T

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunocytochemistry

Mon Jun 01 00:00:00 UTC 2020

Metastasis-initiating cells induce and exploit a fibroblast niche to fuel malignant colonization of the lungs.

Nature communications

Pein M,Insua-Rodríguez J,Hongu T,Riedel A,Meier J,Wiedmann L,Decker K,Essers MAG,Sinn HP,Spaich S,Sütterlin M,Schneeweiss A,Trumpp A,Oskarsson T

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunohistochemistry

Fri Mar 20 00:00:00 UTC 2020

The effects of hedgehog ligand neutralising antibody 5E1 in a mouse model of endometriosis.

BMC research notes

Cousins FL,Farley JK,Kerrigan R,Mukherjee S,Darzi S,Gargett CE,Deane JA

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunocytochemistry

Fri Sep 25 00:00:00 UTC 2020

B Cell Activating Factor (BAFF) Is Required for the Development of Intra-Renal Tertiary Lymphoid Organs in Experimental Kidney Transplantation in Rats.

International journal of molecular sciences

Steines L,Poth H,Herrmann M,Schuster A,Banas B,Bergler T

11-5698 was used in Immunohistochemistry to investigate whether BAFF is required for TLO formation in a full MHC-mismatch Ktx model in rats.

Wed Oct 28 00:00:00 UTC 2020

B Cell Activating Factor (BAFF) Is Required for the Development of Intra-Renal Tertiary Lymphoid Organs in Experimental Kidney Transplantation in Rats.

International journal of molecular sciences

Steines L,Poth H,Herrmann M,Schuster A,Banas B,Bergler T

11-5698 was used in Immunohistochemistry to investigate whether BAFF is required for TLO formation in a full MHC-mismatch Ktx model in rats.

Wed Oct 28 00:00:00 UTC 2020

Nature communications

Mei Y,Han X,Liu Y,Yang J,Sumagin R,Ji P

11-5698 was used in Flow cytometry/Cell sorting to reveal that beta2 integrins are transcriptional targets of SRF.

Tue Jun 23 00:00:00 UTC 2020

Microbiota-Sourced Purines Support Wound Healing and Mucous Barrier Function.

iScience

Lee JS,Wang RX,Goldberg MS,Clifford GP,Kao DJ,Colgan SP

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunohistochemistry (Paraffin)

Fri Jun 26 00:00:00 UTC 2020

Blockade of the AHR restricts a Treg-macrophage suppressive axis induced by L-Kynurenine.

Nature communications

Campesato LF,Budhu S,Tchaicha J,Weng CH,Gigoux M,Cohen IJ,Redmond D,Mangarin L,Pourpe S,Liu C,Zappasodi R,Zamarin D,Cavanaugh J,Castro AC,Manfredi MG,McGovern K,Merghoub T,Wolchok JD

11-5698 was used in Flow cytometry/Cell sorting to show that the AHR pathway is selectively active in IDO/TDO-overexpressing tumors and is associated with resistance to immune checkpoint inhibitors.

Tue Aug 11 00:00:00 UTC 2020

The armed oncolytic adenovirus ZD55-IL-24 eradicates melanoma by turning the tumor cells from the self-state into the nonself-state besides direct killing.

Cell death & disease

Hu HJ,Liang X,Li HL,Du CM,Hao JL,Wang HY,Gu JF,Ni AM,Sun LY,Xiao J,Hu JQ,Yuan H,Dai YS,Jin XT,Zhang KJ,Liu XY

11-5698 was used in Flow cytometry/Cell sorting to elucidate the underlying antitumor mechanism of ZD55-IL-24 in both immunocompetent and immunocompromised mouse model.

Mon Nov 30 00:00:00 UTC 2020

Eradication of tumor growth by delivering novel photothermal selenium-coated tellurium nanoheterojunctions.

Science advances

Chen S,Xing C,Huang D,Zhou C,Ding B,Guo Z,Peng Z,Wang D,Zhu X,Liu S,Cai Z,Wu J,Zhao J,Wu Z,Zhang Y,Wei C,Yan Q,Wang H,Fan D,Liu L,Zhang H,Cao Y

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunocytochemistry

Wed Apr 01 00:00:00 UTC 2020

CXCR4 Signaling Has a CXCL12-Independent Essential Role in Murine MLL-AF9-Driven Acute Myeloid Leukemia.

Cell reports

Ramakrishnan R,Peña-Martínez P,Agarwal P,Rodriguez-Zabala M,Chapellier M,Högberg C,Eriksson M,Yudovich D,Shah M,Ehinger M,Nilsson B,Larsson J,Hagström-Andersson A,Ebert BL,Bhatia R,Järås M

11-5698 was used in Flow cytometry/Cell sorting to identify CXCR4 signaling as essential for AML stem cells by protecting them from differentiation independent of CXCL12 stimulation.

Tue May 26 00:00:00 UTC 2020

Single-cell RNA sequencing identifies shared differentiation paths of mouse thymic innate T cells.

Nature communications

Lee M,Lee E,Han SK,Choi YH,Kwon DI,Choi H,Lee K,Park ES,Rha MS,Joo DJ,Shin EC,Kim S,Kim JK,Lee YJ

11-5698 was used in Flow cytometry/Cell sorting to indicate that innate T cells share effector differentiation processes in the thymus.

Mon Aug 31 00:00:00 UTC 2020

Exercise reduces inflammatory cell production and cardiovascular inflammation via instruction of hematopoietic progenitor cells.

Nature medicine

Frodermann V,Rohde D,Courties G,Severe N,Schloss MJ,Amatullah H,McAlpine CS,Cremer S,Hoyer FF,Ji F,van Koeverden ID,Herisson F,Honold L,Masson GS,Zhang S,Grune J,Iwamoto Y,Schmidt SP,Wojtkiewicz GR,Lee IH,Gustafsson K,Pasterkamp G,de Jager SCA,Sadreyev RI,MacFadyen J,Libby P,Ridker P,Scadden DT,Naxerova K,Jeffrey KL,Swirski FK,Nahrendorf M

11-5698 was used in Flow cytometry/Cell sorting to demonstrate that physical activity alters hematopoietic stem and progenitor cells via modulation of their niche, reducing hematopoietic output of inflammatory leukocytes.

Fri Nov 01 00:00:00 UTC 2019

Unleashing Type-2 Dendritic Cells to Drive Protective Antitumor CD4⁺ T Cell Immunity.

Cell

Binnewies M,Mujal AM,Pollack JL,Combes AJ,Hardison EA,Barry KC,Tsui J,Ruhland MK,Kersten K,Abushawish MA,Spasic M,Giurintano JP,Chan V,Daud AI,Ha P,Ye CJ,Roberts EW,Krummel MF

11-5698 was used in Flow cytometry/Cell sorting to highlight a pathway that restrains cDC2 and whose reversal enhances CD4+ Tconv abundance and controls tumor growth.

Thu Apr 18 00:00:00 UTC 2019

Anti-commensal IgG Drives Intestinal Inflammation and Type 17 Immunity in Ulcerative Colitis.

Immunity

Castro-Dopico T,Dennison TW,Ferdinand JR,Mathews RJ,Fleming A,Clift D,Stewart BJ,Jing C,Strongili K,Labzin LI,Monk EJM,Saeb-Parsy K,Bryant CE,Clare S,Parkes M,Clatworthy MR

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunofluorescence

Tue Apr 16 00:00:00 UTC 2019

Anti-commensal IgG Drives Intestinal Inflammation and Type 17 Immunity in Ulcerative Colitis.

Immunity

Castro-Dopico T,Dennison TW,Ferdinand JR,Mathews RJ,Fleming A,Clift D,Stewart BJ,Jing C,Strongili K,Labzin LI,Monk EJM,Saeb-Parsy K,Bryant CE,Clare S,Parkes M,Clatworthy MR

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunofluorescence

Tue Apr 16 00:00:00 UTC 2019

Mesenchymal Niche-Specific Expression of Cxcl12 Controls Quiescence of Treatment-Resistant Leukemia Stem Cells.

Cell stem cell

Agarwal P,Isringhausen S,Li H,Paterson AJ,He J,Gomariz Á,Nagasawa T,Nombela-Arrieta C,Bhatia R

11-5698-82 was used in Flow Cytometry to highlight a critical role of niche-specific effects of Cxcl12 expression in maintaining quiescence of TKI-resistant LSC populations.

Thu May 02 00:00:00 UTC 2019

TNF-α Coordinates Hematopoietic Stem Cell Survival and Myeloid Regeneration.

Cell stem cell

Yamashita M,Passegué E

11-5698 was used in Flow cytometry/Cell sorting to reveal several TNF-α-mediated pro-survival mechanisms unique to HSCs, highlight an important role for necroptosis in HSC killing, and establish TNF-α as a major pro-survival and pro-regeneration factor for HSCs.

Thu Sep 05 00:00:00 UTC 2019

Sensing of apoptotic cells through Axl causes lung basal cell proliferation in inflammatory diseases.

The Journal of experimental medicine

Fujino N,Brand OJ,Morgan DJ,Fujimori T,Grabiec AM,Jagger CP,Maciewicz RA,Yamada M,Itakura K,Sugiura H,Ichinose M,Hussell T

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunofluorescence

Mon Sep 02 00:00:00 UTC 2019

Sensing of apoptotic cells through Axl causes lung basal cell proliferation in inflammatory diseases.

The Journal of experimental medicine

Fujino N,Brand OJ,Morgan DJ,Fujimori T,Grabiec AM,Jagger CP,Maciewicz RA,Yamada M,Itakura K,Sugiura H,Ichinose M,Hussell T

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunofluorescence

Mon Sep 02 00:00:00 UTC 2019

TFEB Mediates Immune Evasion and Resistance to mTOR Inhibition of Renal Cell Carcinoma via Induction of PD-L1.

Clinical cancer research : an official journal of the American Association for Cancer Research

Zhang C,Duan Y,Xia M,Dong Y,Chen Y,Zheng L,Chai S,Zhang Q,Wei Z,Liu N,Wang J,Sun C,Tang Z,Cheng X,Wu J,Wang G,Zheng F,Laurence A,Li B,Yang XP

11-5698 was used in Flow cytometry/Cell sorting to investigate whether the resistance to mTORi is due to upregulation of PD-L1 and the underlying molecular mechanisms.

Fri Nov 15 00:00:00 UTC 2019

MicroRNA-127-3p controls murine hematopoietic stem cell maintenance by limiting differentiation.

Haematologica

Crisafulli L,Muggeo S,Uva P,Wang Y,Iwasaki M,Locatelli S,Anselmo A,Colombo FS,Carlo-Stella C,Cleary ML,Villa A,Gentner B,Ficara F

11-5698 was used in Flow cytometry/Cell sorting to investigate the contribution of micro-RNA in the regulation of self-renewal vs differentiation.

Sun Sep 01 00:00:00 UTC 2019

SREBP1c-PAX4 Axis Mediates Pancreatic β-Cell Compensatory Responses Upon Metabolic Stress.

Diabetes

Lee G,Jang H,Kim YY,Choe SS,Kong J,Hwang I,Park J,Im SS,Kim JB

11-5698 was used in Immunohistochemistry to study SREBP1c as a mediator of beta-cell compensatory responses during obesity.

Tue Jan 01 00:00:00 UTC 2019

JAK-STAT inhibition impairs K-RAS-driven lung adenocarcinoma progression.

International journal of cancer

Mohrherr J,Haber M,Breitenecker K,Aigner P,Moritsch S,Voronin V,Eferl R,Moriggl R,Stoiber D,Győrffy B,Brcic L,László V,Döme B,Moldvay J,Dezső K,Bilban M,Popper H,Moll HP,Casanova E

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunohistochemistry

Sun Dec 15 00:00:00 UTC 2019

Comprehensive and cell-type-based characterization of the dorsal midbrain during development.

Genes to cells : devoted to molecular & cellular mechanisms

Arimura N,Dewa KI,Okada M,Yanagawa Y,Taya SI,Hoshino M

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunohistochemistry

Tue Jan 01 00:00:00 UTC 2019

Pulsatile MEK Inhibition Improves Anti-tumor Immunity and T Cell Function in Murine Kras Mutant Lung Cancer.

Cell reports

Choi H,Deng J,Li S,Silk T,Dong L,Brea EJ,Houghton S,Redmond D,Zhong H,Boiarsky J,Akbay EA,Smith PD,Merghoub T,Wong KK,Wolchok JD

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Flow Cytometry

Tue Apr 16 00:00:00 UTC 2019

IL-17 inhibits CXCL9/10-mediated recruitment of CD8⁺ cytotoxic T cells and regulatory T cells to colorectal tumors.

Journal for immunotherapy of cancer

Chen J,Ye X,Pitmon E,Lu M,Wan J,Jellison ER,Adler AJ,Vella AT,Wang K

11-5698-82 was used in Flow cytometry/Cell sorting to show that IL-17 mainly signals to tumor cells to promote CRC, but the underlying mechanism remains unclear.

Wed Nov 27 00:00:00 UTC 2019

IL-17 inhibits CXCL9/10-mediated recruitment of CD8⁺ cytotoxic T cells and regulatory T cells to colorectal tumors.

Journal for immunotherapy of cancer

Chen J,Ye X,Pitmon E,Lu M,Wan J,Jellison ER,Adler AJ,Vella AT,Wang K

11-5698-82 was used in Flow cytometry/Cell sorting to show that IL-17 mainly signals to tumor cells to promote CRC, but the underlying mechanism remains unclear.

Wed Nov 27 00:00:00 UTC 2019

Deficiency in the secreted protein Semaphorin3d causes abnormal parathyroid development in mice.

The Journal of biological chemistry

Singh A,Mia MM,Cibi DM,Arya AK,Bhadada SK,Singh MK

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunocytochemistry

Fri May 24 00:00:00 UTC 2019

SORLA regulates endosomal trafficking and oncogenic fitness of HER2.

Nature communications

Pietilä M,Sahgal P,Peuhu E,Jäntti NZ,Paatero I,Närvä E,Al-Akhrass H,Lilja J,Georgiadou M,Andersen OM,Padzik A,Sihto H,Joensuu H,Blomqvist M,Saarinen I,Boström PJ,Taimen P,Ivaska J

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunohistochemistry

Tue May 28 00:00:00 UTC 2019

FCRL5⁺ Memory B Cells Exhibit Robust Recall Responses.

Cell reports

Kim CC,Baccarella AM,Bayat A,Pepper M,Fontana MF

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Flow Cytometry

Tue Apr 30 00:00:00 UTC 2019

Lymphoid Aggregates in the CNS of Progressive Multiple Sclerosis Patients Lack Regulatory T Cells.

Frontiers in immunology

Bell L,Lenhart A,Rosenwald A,Monoranu CM,Berberich-Siebelt F

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunohistochemistry

Thu Oct 22 00:00:00 UTC 2020

Live imaging of alveologenesis in precision-cut lung slices reveals dynamic epithelial cell behaviour.

Nature communications

Akram KM,Yates LL,Mongey R,Rothery S,Gaboriau DCA,Sanderson J,Hind M,Griffiths M,Dean CH

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunofluorescence

Tue Mar 12 00:00:00 UTC 2019

Live imaging of alveologenesis in precision-cut lung slices reveals dynamic epithelial cell behaviour.

Nature communications

Akram KM,Yates LL,Mongey R,Rothery S,Gaboriau DCA,Sanderson J,Hind M,Griffiths M,Dean CH

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunofluorescence

Tue Mar 12 00:00:00 UTC 2019

Soluble TREM2 ameliorates pathological phenotypes by modulating microglial functions in an Alzheimer's disease model.

Nature communications

Zhong L,Xu Y,Zhuo R,Wang T,Wang K,Huang R,Wang D,Gao Y,Zhu Y,Sheng X,Chen K,Wang N,Zhu L,Can D,Marten Y,Shinohara M,Liu CC,Du D,Sun H,Wen L,Xu H,Bu G,Chen XF

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunohistochemistry

Mon Mar 25 00:00:00 UTC 2019

CD109 Restrains Activation of Cutaneous IL-17-Producing γδ T Cells by Commensal Microbiota.

Cell reports

Zhang H,Carnevale G,Polese B,Simard M,Thurairajah B,Khan N,Gentile ME,Fontes G,Vinh DC,Pouliot R,King IL

11-5698-82 was used in Flow Cytometry to provide insight into the regulation of the skin IL-23/IL-17 immune axis and how homeostasis is maintained at this important barrier site.

Tue Oct 08 00:00:00 UTC 2019

Female and male mouse lung group 2 innate lymphoid cells differ in gene expression profiles and cytokine production.

PloS one

Mathä L,Shim H,Steer CA,Yin YH,Martinez-Gonzalez I,Takei F

11-5698-82 was used in Flow Cytometry to suggest that female ILC2s are more readily activated than male ILC2s due to their gene expression at the naïve state, which is potentially influenced by the lung environment.

Mon Dec 16 00:00:00 UTC 2019

Knockdown of Ant2 Reduces Adipocyte Hypoxia And Improves Insulin Resistance in Obesity.

Nature metabolism

Seo JB,Riopel M,Cabrales P,Huh JY,Bandyopadhyay GK,Andreyev AY,Murphy AN,Beeman SC,Smith GI,Klein S,Lee YS,Olefsky JM

11-5698-82 was used in Flow Cytometry to demonstrate that increased adipocyte O2 demand, mediated by ANT2 activity, is the dominant cause of adipocyte hypoxia.

Tue Jan 01 00:00:00 UTC 2019

Adrenergic nerve degeneration in bone marrow drives aging of the hematopoietic stem cell niche.

Nature medicine

Maryanovich M,Zahalka AH,Pierce H,Pinho S,Nakahara F,Asada N,Wei Q,Wang X,Ciero P,Xu J,Leftin A,Frenette PS

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Flow Cytometry

Fri Jun 01 00:00:00 UTC 2018

Modulation of Myelopoiesis Progenitors Is an Integral Component of Trained Immunity.

Cell

Mitroulis I,Ruppova K,Wang B,Chen LS,Grzybek M,Grinenko T,Eugster A,Troullinaki M,Palladini A,Kourtzelis I,Chatzigeorgiou A,Schlitzer A,Beyer M,Joosten LAB,Isermann B,Lesche M,Petzold A,Simons K,Henry I,Dahl A,Schultze JL,Wielockx B,Zamboni N,Mirtschink P,Coskun Ü,Hajishengallis G,Netea MG,Chavakis T

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Flow Cytometry

Thu Jan 11 00:00:00 UTC 2018

A Metabolite-Triggered Tuft Cell-ILC2 Circuit Drives Small Intestinal Remodeling.

Cell

Schneider C,O'Leary CE,von Moltke J,Liang HE,Ang QY,Turnbaugh PJ,Radhakrishnan S,Pellizzon M,Ma A,Locksley RM

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Flow Cytometry

Thu Jul 12 00:00:00 UTC 2018

Quiescent Tissue Stem Cells Evade Immune Surveillance.

Immunity

Agudo J,Park ES,Rose SA,Alibo E,Sweeney R,Dhainaut M,Kobayashi KS,Sachidanandam R,Baccarini A,Merad M,Brown BD

11-5698 was used in Flow cytometry/Cell sorting to identify a link between stem cell quiescence, antigen presentation, and immune evasion.

Tue Feb 20 00:00:00 UTC 2018

Fc Effector Function Contributes to the Activity of Human Anti-CTLA-4 Antibodies.

Cancer cell

Arce Vargas F,Furness AJS,Litchfield K,Joshi K,Rosenthal R,Ghorani E,Solomon I,Lesko MH,Ruef N,Roddie C,Henry JY,Spain L,Ben Aissa A,Georgiou A,Wong YNS,Smith M,Strauss D,Hayes A,Nicol D,O'Brien T,Mårtensson L,Ljungars A,Teige I,Frendéus B,Pule M,Marafioti T,Gore M,Larkin J,Turajlic S,Swanton C,Peggs KS,Quezada SA

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Flow Cytometry

Mon Apr 09 00:00:00 UTC 2018

Dual-targeting Wnt and uPA receptors using peptide conjugated ultra-small nanoparticle drug carriers inhibited cancer stem-cell phenotype in chemo-resistant breast cancer.

Biomaterials

Miller-Kleinhenz J,Guo X,Qian W,Zhou H,Bozeman EN,Zhu L,Ji X,Wang YA,Styblo T,O'Regan R,Mao H,Yang L

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunofluorescence

Mon Jan 01 00:00:00 UTC 2018

Dual-targeting Wnt and uPA receptors using peptide conjugated ultra-small nanoparticle drug carriers inhibited cancer stem-cell phenotype in chemo-resistant breast cancer.

Biomaterials

Miller-Kleinhenz J,Guo X,Qian W,Zhou H,Bozeman EN,Zhu L,Ji X,Wang YA,Styblo T,O'Regan R,Mao H,Yang L

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunofluorescence

Mon Jan 01 00:00:00 UTC 2018

Defining Lineage Potential and Fate Behavior of Precursors during Pancreas Development.

Developmental cell

Sznurkowska MK,Hannezo E,Azzarelli R,Rulands S,Nestorowa S,Hindley CJ,Nichols J,Göttgens B,Huch M,Philpott A,Simons BD

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunofluorescence

Mon Aug 06 00:00:00 UTC 2018

Defining Lineage Potential and Fate Behavior of Precursors during Pancreas Development.

Developmental cell

Sznurkowska MK,Hannezo E,Azzarelli R,Rulands S,Nestorowa S,Hindley CJ,Nichols J,Göttgens B,Huch M,Philpott A,Simons BD

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunofluorescence

Mon Aug 06 00:00:00 UTC 2018

MicroRNA-126 deficiency enhanced the activation and function of CD4⁺ T cells by elevating IRS-1 pathway.

Clinical and experimental immunology

Chu F,Hu Y,Zhou Y,Guo M,Lu J,Zheng W,Xu H,Zhao J,Xu L

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Flow Cytometry

Thu Feb 01 00:00:00 UTC 2018

Generation of mouse-zebrafish hematopoietic tissue chimeric embryos for hematopoiesis and host-pathogen interaction studies.

Disease models & mechanisms

Parada-Kusz M,Penaranda C,Hagedorn EJ,Clatworthy A,Nair AV,Henninger JE,Ernst C,Li B,Riquelme R,Jijon H,Villablanca EJ,Zon LI,Hung D,Allende ML

11-5698 was used in Flow cytometry/Cell sorting to develop a xenotransplantation technique that transiently generates hundreds of haematopoietic tissue chimeric embryos by transplanting murine bone marrow cells into zebrafish blastulae.

Mon Nov 05 00:00:00 UTC 2018

Inhibition of histone deacetylase 1 ameliorates renal tubulointerstitial fibrosis via modulation of inflammation and extracellular matrix gene transcription in mice.

International journal of molecular medicine

Nguyễn-Thanh T,Kim D,Lee S,Kim W,Park SK,Kang KP

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunofluorescence

Mon Jan 01 00:00:00 UTC 2018

Vitreous Cytokine Expression and a Murine Model Suggest a Key Role of Microglia in the Inflammatory Response to Retinal Detachment.

Investigative ophthalmology & visual science

Kiang L,Ross BX,Yao J,Shanmugam S,Andrews CA,Hansen S,Besirli CG,Zacks DN,Abcouwer SF

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunofluorescence

Mon Jul 02 00:00:00 UTC 2018

C-Kit Cardiac Progenitor Cell Based Cell Sheet Improves Vascularization and Attenuates Cardiac Remodeling following Myocardial Infarction in Rats.

BioMed research international

Dergilev K,Tsokolaeva Z,Makarevich P,Beloglazova I,Zubkova E,Boldyreva M,Ratner E,Dyikanov D,Menshikov M,Ovchinnikov A,Ageev F,Parfyonova Y

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunofluorescence

Mon Jan 14 00:00:00 UTC 2019

A morphology independent approach for identifying dividing adult neural stem cells in the mouse hippocampus.

Developmental dynamics : an official publication of the American Association of Anatomists

Harris L,Zalucki O,Oishi S,Burne TH,Jhaveri DJ,Piper M

11-5698 was used in Immunohistochemistry-immunofluorescence to verify using Hes5::GFP mice, that labeling for the cell cycle marker Ki67 and selection against the intermediate progenitor cell marker TBR2 (Ki67+ve ; TBR2-ve nuclei) is sufficient to identify dividing horizontally and radially oriented adult hippocampal neural stem cells in the adult mouse hippocampus.

Mon Jan 01 00:00:00 UTC 2018

ARTS mediates apoptosis and regeneration of the intestinal stem cell niche.

Nature communications

Koren E,Yosefzon Y,Ankawa R,Soteriou D,Jacob A,Nevelsky A,Ben-Yosef R,Bar-Sela G,Fuchs Y

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunofluorescence

Fri Nov 02 00:00:00 UTC 2018

Stem cell factor is selectively secreted by arterial endothelial cells in bone marrow.

Nature communications

Xu C,Gao X,Wei Q,Nakahara F,Zimmerman SE,Mar J,Frenette PS

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Flow Cytometry

Fri Jun 22 00:00:00 UTC 2018

Selective pharmacological inhibition of DDR1 prevents experimentally-induced glomerulonephritis in prevention and therapeutic regime.

Journal of translational medicine

Moll S,Yasui Y,Abed A,Murata T,Shimada H,Maeda A,Fukushima N,Kanamori M,Uhles S,Badi L,Cagarelli T,Formentini I,Drawnel F,Georges G,Bergauer T,Gasser R,Bonfil RD,Fridman R,Richter H,Funk J,Moeller MJ,Chatziantoniou C,Prunotto M

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunohistochemistry (Paraffin)

Fri Jun 01 00:00:00 UTC 2018

Factors Within the Endoneurial Microenvironment Act to Suppress Tumorigenesis of MPNST.

Frontiers in cellular neuroscience

Stratton JA,Assinck P,Sinha S,Kumar R,Moulson A,Patrick N,Raharjo E,Chan JA,Midha R,Tetzlaff W,Biernaskie J

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunocytochemistry

Thu Oct 01 00:00:00 UTC 2020

ATF3 Sustains IL-22-Induced STAT3 Phosphorylation to Maintain Mucosal Immunity Through Inhibiting Phosphatases.

Frontiers in immunology

Glal D,Sudhakar JN,Lu HH,Liu MC,Chiang HY,Liu YC,Cheng CF,Shui JW

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Flow Cytometry

Thu Sep 26 00:00:00 UTC 2019

Pax6 Lengthens G1 Phase and Decreases Oscillating Cdk6 Levels in Murine Embryonic Cortical Progenitors.

Frontiers in cellular neuroscience

Mi D,Manuel M,Huang YT,Mason JO,Price DJ

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Flow Cytometry

Thu Mar 04 00:00:00 UTC 2021

The organic ester O,O'-diethyl-(S,S)-ethylenediamine-N,N'-di-2-(3-cyclohexyl)propanoate dihydrochloride attenuates murine breast cancer growth and metastasis.

Oncotarget

Jurisevic M,Arsenijevic A,Pantic J,Gajovic N,Milovanovic J,Milovanovic M,Poljarevic J,Sabo T,Vojvodic D,Radosavljevic GD,Arsenijevic N

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Flow Cytometry

Fri Jun 15 00:00:00 UTC 2018

Lymphotoxin α fine-tunes T cell clonal deletion by regulating thymic entry of antigen-presenting cells.

Nature communications

Lopes N,Charaix J,Cédile O,Sergé A,Irla M

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Flow Cytometry

Wed Mar 28 00:00:00 UTC 2018

Bcl11b is essential for licensing Th2 differentiation during helminth infection and allergic asthma.

Nature communications

Lorentsen KJ,Cho JJ,Luo X,Zuniga AN,Urban JF,Zhou L,Gharaibeh R,Jobin C,Kladde MP,Avram D

11-5698 was used in Flow cytometry/Cell sorting to establish novel roles for Bcl11b in the regulatory loop that licenses Th2 program in vivo.

Thu Apr 26 00:00:00 UTC 2018

Complement Activation Contributes to Severe Acute Respiratory Syndrome Coronavirus Pathogenesis.

mBio

Gralinski LE,Sheahan TP,Morrison TE,Menachery VD,Jensen K,Leist SR,Whitmore A,Heise MT,Baric RS

11-5698 was used in Flow cytometry/Cell sorting to study complement signalling as regulating a proinflammatory response to SARS-CoV infection.

Tue Oct 09 00:00:00 UTC 2018

Hematopoietic stem cells can differentiate into restricted myeloid progenitors before cell division in mice.

Nature communications

Grinenko T,Eugster A,Thielecke L,Ramasz B,Krüger A,Dietz S,Glauche I,Gerbaulet A,von Bonin M,Basak O,Clevers H,Chavakis T,Wielockx B

11-5698-82 was used in Flow Cytometry to study the mechanisms that control fate decision in adult haematopoietic stem cells.s.

Tue May 15 00:00:00 UTC 2018

Crosstalk between alternative polyadenylation and miRNAs in the regulation of protein translational efficiency.

Genome research

Fu Y,Chen L,Chen C,Ge Y,Kang M,Song Z,Li J,Feng Y,Huo Z,He G,Hou M,Chen S,Xu A

11-5698-82 was used in Flow Cytometry to reveal that the alternative polyadenylation (APA) effect on translational efficiency was mainly regulated by miRNAs, and this regulation was cell cycle dependent.

Thu Nov 01 00:00:00 UTC 2018

Myeloid progenitor cluster formation drives emergency and leukaemic myelopoiesis.

Nature

Hérault A,Binnewies M,Leong S,Calero-Nieto FJ,Zhang SY,Kang YA,Wang X,Pietras EM,Chu SH,Barry-Holson K,Armstrong S,Göttgens B,Passegué E

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Flow Cytometry

Thu Apr 06 00:00:00 UTC 2017

A somatic mutation in erythro-myeloid progenitors causes neurodegenerative disease.

Nature

Mass E,Jacome-Galarza CE,Blank T,Lazarov T,Durham BH,Ozkaya N,Pastore A,Schwabenland M,Chung YR,Rosenblum MK,Prinz M,Abdel-Wahab O,Geissmann F

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Flow Cytometry

Thu Sep 21 00:00:00 UTC 2017

Autophagy maintains the metabolism and function of young and old stem cells.

Nature

Ho TT,Warr MR,Adelman ER,Lansinger OM,Flach J,Verovskaya EV,Figueroa ME,Passegué E

11-5698 was used in Flow cytometry/Cell sorting to demonstrate an essential function for autophagy in removing activated mitochondria and controlling oxidative metabolism, thereby maintaining HSC stemness and regenerative potential.

Thu Mar 09 00:00:00 UTC 2017

De Novo Epigenetic Programs Inhibit PD-1 Blockade-Mediated T Cell Rejuvenation.

Cell

Ghoneim HE,Fan Y,Moustaki A,Abdelsamed HA,Dash P,Dogra P,Carter R,Awad W,Neale G,Thomas PG,Youngblood B

11-5698 was used in Flow cytometry/Cell sorting to study the role of de novo DNA-methylation programming as a regulator of T cell exhaustion and barrier of immune checkpoint blockade-mediated T cell rejuvenation.

Thu Jun 29 00:00:00 UTC 2017

De Novo Epigenetic Programs Inhibit PD-1 Blockade-Mediated T Cell Rejuvenation.

Cell

Ghoneim HE,Fan Y,Moustaki A,Abdelsamed HA,Dash P,Dogra P,Carter R,Awad W,Neale G,Thomas PG,Youngblood B

Thu Jun 29 00:00:00 UTC 2017

White Adipose Tissue Is a Reservoir for Memory T Cells and Promotes Protective Memory Responses to Infection.

Immunity

Han SJ,Glatman Zaretsky A,Andrade-Oliveira V,Collins N,Dzutsev A,Shaik J,Morais da Fonseca D,Harrison OJ,Tamoutounour S,Byrd AL,Smelkinson M,Bouladoux N,Bliska JB,Brenchley JM,Brodsky IE,Belkaid Y

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Flow Cytometry

Tue Dec 19 00:00:00 UTC 2017

Differential cytokine contributions of perivascular haematopoietic stem cell niches.

Nature cell biology

Asada N,Kunisaki Y,Pierce H,Wang Z,Fernandez NF,Birbrair A,Ma'ayan A,Frenette PS

Wed Mar 01 00:00:00 UTC 2017

Antibiotics impair murine hematopoiesis by depleting the intestinal microbiota.

Blood

Josefsdottir KS,Baldridge MT,Kadmon CS,King KY

11-5698 was used in Flow cytometry/Cell sorting to show that microbiome depletion as a result of broad-spectrum antibiotic treatment disrupts basal Stat1 signaling and alters T-cell homeostasis, leading to impaired progenitor maintenance and granulocyte maturation.

Thu Feb 09 00:00:00 UTC 2017

Recruited Monocytes and Type 2 Immunity Promote Lung Regeneration following Pneumonectomy.

Cell stem cell

Lechner AJ,Driver IH,Lee J,Conroy CM,Nagle A,Locksley RM,Rock JR

11-5698 was used in Flow cytometry/Cell sorting to provide evidence that group 2 innate lymphoid cells are a source of IL-13, which promotes lung regeneration.

Thu Jul 06 00:00:00 UTC 2017

Mutations in 5-methylcytosine oxidase TET2 and RhoA cooperatively disrupt T cell homeostasis.

The Journal of clinical investigation

Zang S,Li J,Yang H,Zeng H,Han W,Zhang J,Lee M,Moczygemba M,Isgandarova S,Yang Y,Zhou Y,Rao A,You MJ,Sun D,Huang Y

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Flow Cytometry

Tue Aug 01 00:00:00 UTC 2017

Egr2 and 3 control adaptive immune responses by temporally uncoupling expansion from T cell differentiation.

The Journal of experimental medicine

Miao T,Symonds ALJ,Singh R,Symonds JD,Ogbe A,Omodho B,Zhu B,Li S,Wang P

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Flow Cytometry

Mon Jun 05 00:00:00 UTC 2017

1810011o10 Rik Inhibits the Antitumor Effect of Intratumoral CD8⁺ T Cells through Suppression of Notch2 Pathway in a Murine Hepatocellular Carcinoma Model.

Frontiers in immunology

Dai K,Huang L,Huang YB,Chen ZB,Yang LH,Jiang YA

11-5698 was used in Flow cytometry/Cell sorting to disclose a novel mechanism underlying the negative regulation of antitumour CD8(+) T cells during HCC progression.

Wed Nov 20 00:00:00 UTC 2019

CCR2^- and CCR2⁺ corneal macrophages exhibit distinct characteristics and balance inflammatory responses after epithelial abrasion.

Mucosal immunology

Liu J,Xue Y,Dong D,Xiao C,Lin C,Wang H,Song F,Fu T,Wang Z,Chen J,Pan H,Li Y,Cai D,Li Z

11-5698 was used in Immunofluorescence on wholemounted tissues to show that there are two unique macrophage populations present in the cornea, which both participate in corneal wound healing.

Fri Sep 01 00:00:00 UTC 2017

CCR2^- and CCR2⁺ corneal macrophages exhibit distinct characteristics and balance inflammatory responses after epithelial abrasion.

Mucosal immunology

Liu J,Xue Y,Dong D,Xiao C,Lin C,Wang H,Song F,Fu T,Wang Z,Chen J,Pan H,Li Y,Cai D,Li Z

11-5698 was used in Immunofluorescence on wholemounted tissues to show that there are two unique macrophage populations present in the cornea, which both participate in corneal wound healing.

Fri Sep 01 00:00:00 UTC 2017

Hydrogen-Rich Water Ameliorates Total Body Irradiation-Induced Hematopoietic Stem Cell Injury by Reducing Hydroxyl Radical.

Oxidative medicine and cellular longevity

Zhang J,Xue X,Han X,Li Y,Lu L,Li D,Fan S

Thu Mar 16 00:00:00 UTC 2017

Hypoxia-Inducible Factor 1α Signaling Promotes Repair of the Alveolar Epithelium after Acute Lung Injury.

The American journal of pathology

McClendon J,Jansing NL,Redente EF,Gandjeva A,Ito Y,Colgan SP,Ahmad A,Riches DWH,Chapman HA,Mason RJ,Tuder RM,Zemans RL

11-5698 was used in Flow cytometry/Cell sorting to study whether hypoxia-inducible factor 1α promotes proliferation and spreading of alveolar type II cells during repair after lung injury.

Tue Aug 01 00:00:00 UTC 2017

Cell-type-specific expression of NFIX in the developing and adult cerebellum.

Brain structure & function

Fraser J,Essebier A,Gronostajski RM,Boden M,Wainwright BJ,Harvey TJ,Piper M

11569882 was used in immunohistochemistry to report that nuclear factor one X aids in regulating progenitor cell biology within the embryonic and post-natal cerebellum and has a role within multiple neuronal and glial populations within the adult cerebellum

Sat Jul 01 00:00:00 UTC 2017

Erythropoietin enhances Kupffer cell number and activity in the challenged liver.

Scientific reports

Gilboa D,Haim-Ohana Y,Deshet-Unger N,Ben-Califa N,Hiram-Bab S,Reuveni D,Zigmond E,Gassmann M,Gabet Y,Varol C,Neumann D

Mon Sep 04 00:00:00 UTC 2017

Histone variant H2A.J accumulates in senescent cells and promotes inflammatory gene expression.

Nature communications

Contrepois K,Coudereau C,Benayoun BA,Schuler N,Roux PF,Bischof O,Courbeyrette R,Carvalho C,Thuret JY,Ma Z,Derbois C,Nevers MC,Volland H,Redon CE,Bonner WM,Deleuze JF,Wiel C,Bernard D,Snyder MP,Rübe CE,Olaso R,Fenaille F,Mann C

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunofluorescence

Wed May 10 00:00:00 UTC 2017

IL-4 as a Repurposed Biological Drug for Myocardial Infarction through Augmentation of Reparative Cardiac Macrophages: Proof-of-Concept Data in Mice.

Scientific reports

Shintani Y,Ito T,Fields L,Shiraishi M,Ichihara Y,Sato N,Podaru M,Kainuma S,Tanaka H,Suzuki K

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunofluorescence

Mon Jul 31 00:00:00 UTC 2017

Neonatal pancreatic pericytes support β-cell proliferation.

Molecular metabolism

Epshtein A,Rachi E,Sakhneny L,Mizrachi S,Baer D,Landsman L

Sun Oct 01 00:00:00 UTC 2017

The Ror1 receptor tyrosine kinase plays a critical role in regulating satellite cell proliferation during regeneration of injured muscle.

The Journal of biological chemistry

Kamizaki K,Doi R,Hayashi M,Saji T,Kanagawa M,Toda T,Fukada SI,Ho HH,Greenberg ME,Endo M,Minami Y

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunocytochemistry

Fri Sep 22 00:00:00 UTC 2017

A Mouse Model of West Nile Virus Infection.

Current protocols in mouse biology

Graham JB,Swarts JL,Lund JM

11-5698 was used in Flow cytometry/Cell sorting to develop a mouse model to study the breadth of symptoms and disease severity seen in human West Nile virus infection.

Wed Dec 20 00:00:00 UTC 2017

Interleukin-21 combined with PD-1 or CTLA-4 blockade enhances antitumor immunity in mouse tumor models.

Oncoimmunology

Lewis KE,Selby MJ,Masters G,Valle J,Dito G,Curtis WR,Garcia R,Mink KA,Waggie KS,Holdren MS,Grosso JF,Korman AJ,Jure-Kunkel M,Dillon SR

11-5698 was used in Flow cytometry/Cell sorting to investigate the efficacy of immune-modulatory interleukin-21 combined with checkpoint blockade in several syngeneic mouse tumor models.

Tue Jan 12 00:00:00 UTC 2021

Hyaluronan and TLR4 promote surfactant-protein-C-positive alveolar progenitor cell renewal and prevent severe pulmonary fibrosis in mice.

Nature medicine

Liang J,Zhang Y,Xie T,Liu N,Chen H,Geng Y,Kurkciyan A,Mena JM,Stripp BR,Jiang D,Noble PW

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunocytochemistry

Tue Nov 01 00:00:00 UTC 2016

Image-based detection and targeting of therapy resistance in pancreatic adenocarcinoma.

Nature

Fox RG,Lytle NK,Jaquish DV,Park FD,Ito T,Bajaj J,Koechlein CS,Zimdahl B,Yano M,Kopp J,Kritzik M,Sicklick J,Sander M,Grandgenett PM,Hollingsworth MA,Shibata S,Pizzo D,Valasek M,Sasik R,Scadeng M,Okano H,Kim Y,MacLeod AR,Lowy AM,Reya T

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunofluorescence

Thu Jun 16 00:00:00 UTC 2016

Host-Protozoan Interactions Protect from Mucosal Infections through Activation of the Inflammasome.

Cell

Chudnovskiy A,Mortha A,Kana V,Kennard A,Ramirez JD,Rahman A,Remark R,Mogno I,Ng R,Gnjatic S,Amir ED,Solovyov A,Greenbaum B,Clemente J,Faith J,Belkaid Y,Grigg ME,Merad M

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunofluorescence

Thu Oct 06 00:00:00 UTC 2016

Lineage-specific enhancers activate self-renewal genes in macrophages and embryonic stem cells.

Science (New York, N.Y.)

Soucie EL,Weng Z,Geirsdóttir L,Molawi K,Maurizio J,Fenouil R,Mossadegh-Keller N,Gimenez G,VanHille L,Beniazza M,Favret J,Berruyer C,Perrin P,Hacohen N,Andrau JC,Ferrier P,Dubreuil P,Sidow A,Sieweke MH

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunofluorescence

Fri Feb 12 00:00:00 UTC 2016

RANKL/RANK control Brca1 mutation- .

Cell research

Sigl V,Owusu-Boaitey K,Joshi PA,Kavirayani A,Wirnsberger G,Novatchkova M,Kozieradzki I,Schramek D,Edokobi N,Hersl J,Sampson A,Odai-Afotey A,Lazaro C,Gonzalez-Suarez E,Pujana MA,Cimba F,Heyn H,Vidal E,Cruickshank J,Berman H,Sarao R,Ticevic M,Uribesalgo I,Tortola L,Rao S,Tan Y,Pfeiler G,Lee EY,Bago-Horvath Z,Kenner L,Popper H,Singer C,Khokha R,Jones LP,Penninger JM

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunohistochemistry

Fri Jul 01 00:00:00 UTC 2016

Foxp3 and Toll-like receptor signaling balance T_reg cell anabolic metabolism for suppression.

Nature immunology

Gerriets VA,Kishton RJ,Johnson MO,Cohen S,Siska PJ,Nichols AG,Warmoes MO,de Cubas AA,MacIver NJ,Locasale JW,Turka LA,Wells AD,Rathmell JC

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Flow Cytometry

Thu Dec 01 00:00:00 UTC 2016

Oligodendrocyte death results in immune-mediated CNS demyelination.

Nature neuroscience

Traka M,Podojil JR,McCarthy DP,Miller SD,Popko B

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Flow Cytometry

Fri Jan 01 00:00:00 UTC 2016

Chronic interleukin-1 exposure drives haematopoietic stem cells towards precocious myeloid differentiation at the expense of self-renewal.

Nature cell biology

Pietras EM,Mirantes-Barbeito C,Fong S,Loeffler D,Kovtonyuk LV,Zhang S,Lakshminarasimhan R,Chin CP,Techner JM,Will B,Nerlov C,Steidl U,Manz MG,Schroeder T,Passegué E

11-5698 was used in Flow cytometry/Cell sorting to identify a critical regulatory circuit that tailors HSC responses to acute needs, and is likely to underlie deregulated blood homeostasis in chronic inflammation conditions.

Wed Jun 01 00:00:00 UTC 2016

Functional screen identifies regulators of murine hematopoietic stem cell repopulation.

The Journal of experimental medicine

Holmfeldt P,Ganuza M,Marathe H,He B,Hall T,Kang G,Moen J,Pardieck J,Saulsberry AC,Cico A,Gaut L,McGoldrick D,Finkelstein D,Tan K,McKinney-Freeman S

11-5698 was used in Flow cytometry/Cell sorting to discover novel regulators of hematopoietic stem and progenitor cell repopulation in mice.

Mon Mar 07 00:00:00 UTC 2016

Repression of p53-target gene Bbc3/PUMA by MYSM1 is essential for the survival of hematopoietic multipotent progenitors and contributes to stem cell maintenance.

Cell death and differentiation

Belle JI,Petrov JC,Langlais D,Robert F,Cencic R,Shen S,Pelletier J,Gros P,Nijnik A

11-5698 was used in Flow cytometry/Cell sorting to elucidate the mechanisms underlying the transcriptional activation of p53 stress responses in Mysm1-deficient haematopoietic stem and progenitor cells.

Sun May 01 00:00:00 UTC 2016

Immunosuppressive evidence of Tityus serrulatus toxins Ts6 and Ts15: insights of a novel K(+) channel pattern in T cells.

Immunology

Pucca MB,Bertolini TB,Cerni FA,Bordon KC,Peigneur S,Tytgat J,Bonato VL,Arantes EC

11-5698 was used in Flow cytometry/Cell sorting to study the immunosuppressant role of Tityus serrulatus toxins on CD4+ subsets.

Mon Feb 01 00:00:00 UTC 2016

Schwann cell proliferation and differentiation that is induced by ferulic acid through MEK1/ERK1/2 signalling promotes peripheral nerve remyelination following crush injury in rats.

Experimental and therapeutic medicine

Zhu X,Li K,Guo X,Wang J,Xiang Y

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Flow Cytometry

Thu Sep 01 00:00:00 UTC 2016

Detection of Cell Proliferation Markers by Immunofluorescence Staining and Microscopy Imaging in Paraffin-Embedded Tissue Sections.

Current protocols in molecular biology

Eminaga S,Teekakirikul P,Seidman CE,Seidman JG

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunofluorescence

Fri Jul 01 00:00:00 UTC 2016

Growth and metastasis of lung adenocarcinoma is potentiated by BMP4-mediated immunosuppression.

Oncoimmunology

Chen L,Yi X,Goswami S,Ahn YH,Roybal JD,Yang Y,Diao L,Peng D,Peng D,Fradette JJ,Wang J,Byers LA,Kurie JM,Ullrich SE,Qin FX,Gibbons DL

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Flow Cytometry

Tue Jan 12 00:00:00 UTC 2021

The stress kinase GCN2 does not mediate suppression of antitumor T cell responses by tryptophan catabolism in experimental melanomas.

Oncoimmunology

Sonner JK,Deumelandt K,Ott M,Thomé CM,Rauschenbach KJ,Schulz S,Munteanu B,Mohapatra S,Adam I,Hofer AC,Feuerer M,Opitz CA,Hopf C,Wick W,Platten M

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Flow Cytometry

Tue Jan 12 00:00:00 UTC 2021

The cell proliferation antigen Ki-67 organises heterochromatin.

eLife

Sobecki M,Mrouj K,Camasses A,Parisis N,Nicolas E,Llères D,Gerbe F,Prieto S,Krasinska L,David A,Eguren M,Birling MC,Urbach S,Hem S,Déjardin J,Malumbres M,Jay P,Dulic V,Lafontaine DLj,Feil R,Fisher D

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Western Blot

Mon Mar 07 00:00:00 UTC 2016

The cell proliferation antigen Ki-67 organises heterochromatin.

eLife

Sobecki M,Mrouj K,Camasses A,Parisis N,Nicolas E,Llères D,Gerbe F,Prieto S,Krasinska L,David A,Eguren M,Birling MC,Urbach S,Hem S,Déjardin J,Malumbres M,Jay P,Dulic V,Lafontaine DLj,Feil R,Fisher D

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Western Blot

Mon Mar 07 00:00:00 UTC 2016

The cell proliferation antigen Ki-67 organises heterochromatin.

eLife

Sobecki M,Mrouj K,Camasses A,Parisis N,Nicolas E,Llères D,Gerbe F,Prieto S,Krasinska L,David A,Eguren M,Birling MC,Urbach S,Hem S,Déjardin J,Malumbres M,Jay P,Dulic V,Lafontaine DLj,Feil R,Fisher D

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Western Blot

Mon Mar 07 00:00:00 UTC 2016

The cell proliferation antigen Ki-67 organises heterochromatin.

eLife

Sobecki M,Mrouj K,Camasses A,Parisis N,Nicolas E,Llères D,Gerbe F,Prieto S,Krasinska L,David A,Eguren M,Birling MC,Urbach S,Hem S,Déjardin J,Malumbres M,Jay P,Dulic V,Lafontaine DLj,Feil R,Fisher D

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Western Blot

Mon Mar 07 00:00:00 UTC 2016

The cell proliferation antigen Ki-67 organises heterochromatin.

eLife

Sobecki M,Mrouj K,Camasses A,Parisis N,Nicolas E,Llères D,Gerbe F,Prieto S,Krasinska L,David A,Eguren M,Birling MC,Urbach S,Hem S,Déjardin J,Malumbres M,Jay P,Dulic V,Lafontaine DLj,Feil R,Fisher D

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Western Blot

Mon Mar 07 00:00:00 UTC 2016

The cell proliferation antigen Ki-67 organises heterochromatin.

eLife

Sobecki M,Mrouj K,Camasses A,Parisis N,Nicolas E,Llères D,Gerbe F,Prieto S,Krasinska L,David A,Eguren M,Birling MC,Urbach S,Hem S,Déjardin J,Malumbres M,Jay P,Dulic V,Lafontaine DLj,Feil R,Fisher D

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Western Blot

Mon Mar 07 00:00:00 UTC 2016

The cell proliferation antigen Ki-67 organises heterochromatin.

eLife

Sobecki M,Mrouj K,Camasses A,Parisis N,Nicolas E,Llères D,Gerbe F,Prieto S,Krasinska L,David A,Eguren M,Birling MC,Urbach S,Hem S,Déjardin J,Malumbres M,Jay P,Dulic V,Lafontaine DLj,Feil R,Fisher D

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Western Blot

Mon Mar 07 00:00:00 UTC 2016

The cell proliferation antigen Ki-67 organises heterochromatin.

eLife

Sobecki M,Mrouj K,Camasses A,Parisis N,Nicolas E,Llères D,Gerbe F,Prieto S,Krasinska L,David A,Eguren M,Birling MC,Urbach S,Hem S,Déjardin J,Malumbres M,Jay P,Dulic V,Lafontaine DLj,Feil R,Fisher D

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Western Blot

Mon Mar 07 00:00:00 UTC 2016

Immune response modulation by Galectin-1 in a transgenic model of neuroblastoma.

Oncoimmunology

Büchel G,Schulte JH,Harrison L,Batzke K,Schüller U,Hansen W,Schramm A

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Flow Cytometry

Sun May 01 00:00:00 UTC 2016

Heterogeneous fibroblasts underlie age-dependent tertiary lymphoid tissues in the kidney.

JCI insight

Sato Y,Mii A,Hamazaki Y,Fujita H,Nakata H,Masuda K,Nishiyama S,Shibuya S,Haga H,Ogawa O,Shimizu A,Narumiya S,Kaisho T,Arita M,Yanagisawa M,Miyasaka M,Sharma K,Minato N,Kawamoto H,Yanagita M

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunofluorescence

Thu Jul 21 00:00:00 UTC 2016

Whole Chromosome Instability induces senescence and promotes SASP.

Scientific reports

Andriani GA,Almeida VP,Faggioli F,Mauro M,Tsai WL,Santambrogio L,Maslov A,Gadina M,Campisi J,Vijg J,Montagna C

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunofluorescence

Wed Oct 12 00:00:00 UTC 2016

Whole Chromosome Instability induces senescence and promotes SASP.

Scientific reports

Andriani GA,Almeida VP,Faggioli F,Mauro M,Tsai WL,Santambrogio L,Maslov A,Gadina M,Campisi J,Vijg J,Montagna C

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunofluorescence

Wed Oct 12 00:00:00 UTC 2016

Suppression of ischemia in arterial occlusive disease by JNK-promoted native collateral artery development.

eLife

Ramo K,Sugamura K,Craige S,Keaney JF,Davis RJ

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunofluorescence

Tue Aug 09 00:00:00 UTC 2016

Mice lacking Programmed cell death-1 show a role for CD8(+) T cells in long-term immunity against blood-stage malaria.

Scientific reports

Horne-Debets JM,Karunarathne DS,Faleiro RJ,Poh CM,Renia L,Wykes MN

11-5698 was used in Flow cytometry/Cell sorting to demonstrate parasite-specific CD8(+) T cells in PD-1KO mice confer enhanced long-term malarial immunity.

Tue May 24 00:00:00 UTC 2016

SCIB1, a huIgG1 antibody DNA vaccination, combined with PD-1 blockade induced efficient therapy of poorly immunogenic tumors.

Oncotarget

Xue W,Brentville VA,Symonds P,Cook KW,Yagita H,Metheringham RL,Durrant LG

11-5698 was used in Flow cytometry/Cell sorting to investigate the anti-tumour effect of a huIgG1 antibody DNA vaccine and PD-1 blockade.

Tue Dec 13 00:00:00 UTC 2016

Deficiency of the TLR4 analogue RP105 aggravates vein graft disease by inducing a pro-inflammatory response.

Scientific reports

Wezel A,de Vries MR,Maassen JM,Kip P,Peters EA,Karper JC,Kuiper J,Bot I,Quax PHA

11-5698 was used in Flow cytometry/Cell sorting to determine aggravated vein graft disease caused by RP105 deficiency results from an increased local inflammatory response.

Thu Apr 07 00:00:00 UTC 2016

Epithelial-to-mesenchymal transition induces cell cycle arrest and parenchymal damage in renal fibrosis.

Nature medicine

Lovisa S,LeBleu VS,Tampe B,Sugimoto H,Vadnagara K,Carstens JL,Wu CC,Hagos Y,Burckhardt BC,Pentcheva-Hoang T,Nischal H,Allison JP,Zeisberg M,Kalluri R

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunofluorescence

Tue Sep 01 00:00:00 UTC 2015

Low levels of endogenous or X-ray-induced DNA double-strand breaks activate apoptosis in adult neural stem cells.

Journal of cell science

Barazzuol L,Rickett N,Ju L,Jeggo PA

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunofluorescence

Thu Oct 01 00:00:00 UTC 2015

Mammary Stem Cells and Tumor-Initiating Cells Are More Resistant to Apoptosis and Exhibit Increased DNA Repair Activity in Response to DNA Damage.

Stem cell reports

Chang CH,Zhang M,Rajapakshe K,Coarfa C,Edwards D,Huang S,Rosen JM

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Flow Cytometry

Tue Sep 08 00:00:00 UTC 2015

The adhesion G protein-coupled receptor GPR56 is a cell-autonomous regulator of oligodendrocyte development.

Nature communications

Giera S,Deng Y,Luo R,Ackerman SD,Mogha A,Monk KR,Ying Y,Jeong SJ,Makinodan M,Bialas AR,Chang BS,Stevens B,Corfas G,Piao X

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunofluorescence

Wed Jan 21 00:00:00 UTC 2015

NF-κB-induced microRNA-31 promotes epidermal hyperplasia by repressing protein phosphatase 6 in psoriasis.

Nature communications

Yan S,Xu Z,Lou F,Zhang L,Ke F,Bai J,Liu Z,Liu J,Wang H,Zhu H,Sun Y,Cai W,Gao Y,Su B,Li Q,Yang X,Yu J,Lai Y,Yu XZ,Zheng Y,Shen N,Chin YE,Wang H

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunohistochemistry

Fri Jul 03 00:00:00 UTC 2015

Mesenchymal Stem Cells Reduce Murine Atherosclerosis Development.

Scientific reports

Frodermann V,van Duijn J,van Pel M,van Santbrink PJ,Bot I,Kuiper J,de Jager SC

11-5698 was used in Flow cytometry/Cell sorting to study how MSC treatment affects not only inflammatory responses but also significantly reduces dyslipidaemia in mice.

Thu Oct 22 00:00:00 UTC 2015

Alveolar progenitor and stem cells in lung development, renewal and cancer.

Nature

Desai TJ,Brownfield DG,Krasnow MA

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunofluorescence

Thu Mar 13 00:00:00 UTC 2014

The tyrosine phosphatase PTPN22 discriminates weak self peptides from strong agonist TCR signals.

Nature immunology

Salmond RJ,Brownlie RJ,Morrison VL,Zamoyska R

11-5698 was used in Flow cytometry/Cell sorting to study how loss-of-function PTPN22 alleles can lead to the population expansion of effector and/or memory T cells and a predisposition to human autoimmunity.

Mon Sep 01 00:00:00 UTC 2014

Differential contribution of monocytes to heart macrophages in steady-state and after myocardial infarction.

Circulation research

Heidt T,Courties G,Dutta P,Sager HB,Sebas M,Iwamoto Y,Sun Y,Da Silva N,Panizzi P,van der Laan AM,Swirski FK,Weissleder R,Nahrendorf M

11-5698 was used in Flow cytometry/Cell sorting to show differential contribution of monocytes to heart macrophages during steady state, after macrophage depletion or after myocardial infarction.

Mon Jul 07 00:00:00 UTC 2014

Inflammatory monocytes promote progression of Duchenne muscular dystrophy and can be therapeutically targeted via CCR2.

EMBO molecular medicine

Mojumdar K,Liang F,Giordano C,Lemaire C,Danialou G,Okazaki T,Bourdon J,Rafei M,Galipeau J,Divangahi M,Petrof BJ

11-5698 was used in Flow cytometry/Cell sorting to determine the role of macrophages in Duchenne muscular dystrophy pathogenesis.

Sat Nov 01 00:00:00 UTC 2014

The Notch1 transcriptional activation domain is required for development and reveals a novel role for Notch1 signaling in fetal hematopoietic stem cells.

Genes & development

Gerhardt DM,Pajcini KV,D'altri T,Tu L,Jain R,Xu L,Chen MJ,Rentschler S,Shestova O,Wertheim GB,Tobias JW,Kluk M,Wood AW,Aster JC,Gimotty PA,Epstein JA,Speck N,Bigas A,Pear WS

11-5698 was used in Flow cytometry/Cell sorting to describe additional functions for Notch1 in embryonic haematopoietic stem cell biology.

Sat Mar 15 00:00:00 UTC 2014

Metastasis is regulated via microRNA-200/ZEB1 axis control of tumour cell PD-L1 expression and intratumoral immunosuppression.

Nature communications

Chen L,Gibbons DL,Goswami S,Cortez MA,Ahn YH,Byers LA,Zhang X,Yi X,Dwyer D,Lin W,Diao L,Wang J,Roybal J,Patel M,Ungewiss C,Peng D,Antonia S,Mediavilla-Varela M,Robertson G,Suraokar M,Welsh JW,Erez B,Wistuba II,Chen L,Peng D,Wang S,Ullrich SE,Heymach JV,Kurie JM,Qin FX

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Flow Cytometry

Tue Oct 28 00:00:00 UTC 2014

Dedifferentiation of committed epithelial cells into stem cells in vivo.

Nature

Tata PR,Mou H,Pardo-Saganta A,Zhao R,Prabhu M,Law BM,Vinarsky V,Cho JL,Breton S,Sahay A,Medoff BD,Rajagopal J

Published figure using Ki-67 monoclonal antibody (Product # 11-5698-82) in Immunofluorescence

Thu Nov 14 00:00:00 UTC 2013

Arteriolar niches maintain haematopoietic stem cell quiescence.

Nature

Kunisaki Y,Bruns I,Scheiermann C,Ahmed J,Pinho S,Zhang D,Mizoguchi T,Wei Q,Lucas D,Ito K,Mar JC,Bergman A,Frenette PS

11-5698 was used in Flow cytometry/Cell sorting to investigate the spatial localisation of quiescent haematopoietic stem cells in bone marrow, showing that arteriolar niches maintain quiescence.

Thu Oct 31 00:00:00 UTC 2013

IL-1R signaling in dendritic cells replaces pattern-recognition receptors in promoting CD8⁺ T cell responses to influenza A virus.

Nature immunology

Pang IK,Ichinohe T,Iwasaki A

Fri Mar 01 00:00:00 UTC 2013

Smooth muscle cells differentiated from reprogrammed embryonic lung fibroblasts through DKK3 signaling are potent for tissue engineering of vascular grafts.

Circulation research

Karamariti E,Margariti A,Winkler B,Wang X,Hong X,Baban D,Ragoussis J,Huang Y,Han JD,Wong MM,Sag CM,Shah AM,Hu Y,Xu Q

11-5698 was used in Flow cytometry/Cell sorting to develop a protocol to generate smooth muscle cells from partially-induced pluripotent stem cells through a dickkopf 3 signalling pathway.

Fri May 24 00:00:00 UTC 2013

Primate B-1 cells generate antigen-specific B cell responses to T cell-independent type 2 antigens.

Journal of immunology (Baltimore, Md. : 1950)

Yammani RD,Haas KM

Mon Apr 01 00:00:00 UTC 2013

Myeloid cells expressing VEGF and arginase-1 following uptake of damaged retinal pigment epithelium suggests potential mechanism that drives the onset of choroidal angiogenesis in mice.

PloS one

Liu J,Copland DA,Horie S,Wu WK,Chen M,Xu Y,Paul Morgan B,Mack M,Xu H,Nicholson LB,Dick AD

Thu Jan 15 00:00:00 UTC 2015

Myeloid cells expressing VEGF and arginase-1 following uptake of damaged retinal pigment epithelium suggests potential mechanism that drives the onset of choroidal angiogenesis in mice.

PloS one

Liu J,Copland DA,Horie S,Wu WK,Chen M,Xu Y,Paul Morgan B,Mack M,Xu H,Nicholson LB,Dick AD

Thu Jan 15 00:00:00 UTC 2015

Small intestine inflammation in Roquin-mutant and Roquin-deficient mice.

PloS one

Schaefer JS,Montufar-Solis D,Nakra N,Vigneswaran N,Klein JR

Tue Sep 03 00:00:00 UTC 2013

Bioinformatics

Protein Aliases: Antigen identified by monoclonal antibody Ki-67; Antigen identified by monoclonal antibody Ki-67 homolog; Antigen KI-67; Antigen KI-67 homolog; Proliferation marker protein Ki-67; proliferation-related Ki-67 antigen; protein phosphatase 1, regulatory subunit 105; RP11-380J17.2

View more View less

Gene Aliases: D630048A14Rik; Ki-67; Ki67; KIA; MIB-; MIB-1; MKI67; PPP1R105

View more View less

UniProt ID: (Human) P46013, (Mouse) E9PVX6

View more View less

Entrez Gene ID: (Dog) 100686578, (Human) 4288, (Cynomolgus monkey) 102135895, (Rat) 291234, (Mouse) 17345

View more View less

Function(s)

protein binding ATP binding protein C-terminus binding poly(A) RNA binding molecular_function

Process(es)

DNA metabolic process meiotic nuclear division cell proliferation response to organic cyclic compound hyaluronan metabolic process organ regeneration cellular response to heat hepatocyte proliferation cholangiocyte proliferation

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more

Ki-67 Monoclonal Antibody (SolA15), FITC, eBioscience™

Ki-67 Antibody (11-5698-82) in ICC/IF, IHC (P)

Product Details

11-5698-82

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunohistochemistry (PFA fixed) (IHC (PFA))

Immunohistochemistry (Frozen) (IHC (F))

Immunocytochemistry (ICC/IF)

Flow Cytometry (Flow)

Functional Assay (Functional)

Miscellaneous PubMed (MISC)

Species Reactivity

Published species

Host/Isotype

Recommended Isotype Control

Class

Type

Clone

Conjugate

Excitation/Emission Max

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

RRID

Product Specific Information

Target Information

How to use the Panel Builder

Bioinformatics

Performance Guarantee

We're here to help

Your items have has been added!