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Invitrogen
Kininogen Light Chain Monoclonal Antibody (288424)
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Product Details
MA5-23989
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rat
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
288424
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse Kininogen Glu21-Ser661
Conjugate
Form
Lyophilized
Concentration
0.5 mg/mL
Purification
Protein A/G
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2610487
Product Specific Information
In Western blots, reacts with full length Kininogen (aa 21-661) and several forms of the light chain starting at residue 389, and does not react with the heavy chain. In Western blots, no cross-reactivity with recombinant mouse (rm) Cystatin A, B, C, E/M, recombinant human (rh) Cystatin D, F, S, SA, SN, rmCystatin/Stefin Homolog, rmFetuin A, rhFetuin B, rmHPRG, rhKininogen, or rhKininostatin is observed.
Reconstitute at 0.5 mg/mL in sterile PBS.
Target Information
This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: H-kininigen; Kininogen-1; L-kininogen
Gene Aliases: Kng; Kng1
UniProt ID: (Mouse) Q91XK5
Entrez Gene ID: (Mouse) 16644
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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