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Invitrogen
Kir2.3 (KCNJ4) Polyclonal Antibody
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FIGURE: 1 / 10
Kir2.3 (KCNJ4) Antibody (PA5-102023) in ICC/IF
Immunocytochemistry analysis of Kir2.3 (KCNJ4) in A549 cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with Kir2.3 (KCNJ4) polyclonal antibody (Product # PA5-102023) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG(H+L) (Red) and an AlexaFluor488 co... View More
Product Details
PA5-102023
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human KCNJ4(Accession P48050), corresponding to amino acid residues R252-Q302.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2851454
Product Specific Information
Antibody detects endogenous levels of total KCNJ4.
Target Information
Several different potassium channels are known to be involved with electrical signaling in the nervous system. One class is activated by depolarization whereas a second class is not. The latter are referred to as inwardly rectifying K+ channels, and they have a greater tendency to allow potassium to flow into the cell rather than out of it. This asymmetry in potassium ion conductance plays a key role in the excitability of muscle cells and neurons. The protein encoded by this gene is an integral membrane protein and member of the inward rectifier potassium channel family. The encoded protein has a small unitary conductance compared to other members of this protein family. Two transcript variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: BIR11; Brain inwardly rectifying K(+) channel 2; Hippocampal inward rectifier; hippocampal inward rectifier potassium channel; HIR; HIRK2; HRK1; Inward rectifier K(+) channel Kir2.3; Inward rectifier potassium channel 4; IRK-3; IRK3; Kir 2.3; Potassium channel, inwardly rectifying subfamily J member 4; potassium channel, inwardly rectifying subfamily J, member 4; potassium inwardly-rectifying channel, subfamily J, member 4
Gene Aliases: HIR; HIRK2; HRK1; IRK-3; IRK3; Kcnf2; KCNJ4; Kir2.3; MB-IRK3
UniProt ID: (Human) P48050, (Rat) P52190
Entrez Gene ID: (Human) 3761, (Mouse) 16520, (Rat) 116649
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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