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Invitrogen
L-Ficolin Polyclonal Antibody
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FIGURE: 1 / 1
L-Ficolin Antibody (PA5-120478) in WB
Western blot analysis of L-Ficolin in extracts of various cell lines. Samples were incubated with L-Ficolin Polyclonal antibody (Product # PA5-120478) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Product Details
PA5-120478
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 230-290 of human FCN2 (NP_004099.2).
Conjugate
Form
Liquid
Concentration
0.74 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2914050
Product Specific Information
Positive test controls include: mosue spleen, mouse lung, rat spleen.
Immunogen sequence: SAGDSLTFHN NQSFSTKDQD NDLNTGNCAV MFQGAWWYKN CHVSNLNGRY LRGTHGSFAN G
Target Information
L-Ficolin (Ficolin-2) is an innate immunity pattern recognition molecule found in human serum. L-Ficolin binds to distinct pathogen-associated molecular patterns (PAMP), such as carbohydrates (GlcNAc), lipoteichoic acid and acetylated groups thereby facilitating phagocytosis and activation of complement through the lectin route using the same serine proteases as mannose-binding lectin (MBL) named MASP ((MBL)-associated serine protease).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 37 kDa elastin-binding protein; Collagen/fibrinogen domain-containing protein 2; EBP-37; ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin); ficolin B; Ficolin-2; Ficolin-B; Ficolin-beta; Hucolin; L-ficolin; RP11-263F14.2; Serum lectin p35
Gene Aliases: EBP-37; FCN2; FCNL; ficolin-2; P35
UniProt ID: (Human) Q15485
Entrez Gene ID: (Human) 2220
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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