Proteintech

LAMB3 Polyclonal Antibody

FIGURE: 1 / 1

LAMB3 Antibody (26795-1-AP) in WB

A431 cells were subjected to SDS PAGE followed by western blot with 26795-1-AP (LAMB3 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours.

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Product Details

26795-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:6,000

View 5 publications 5 publications

Immunohistochemistry (IHC)

View 3 publications 3 publications

Immunocytochemistry (ICC/IF)

View 2 publications 2 publications

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

LAMB3 Fusion Protein Ag25192 (828-1172 aa encoded by BC075838)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.4 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: AFLMAGQVA EQLRGFNAQL QRTRQMIRAA EESASQIQSS AQRLETQVSA SRSQMEEDVR RTRLLIQQVR DFLTDPDTDA ATIQEVSEAV LALWLPTDSA TVLQKMNEIQ AIAARLPNVD LVLSQTKQDI ARARRLQAEA EEARSRAHAV EGQVEDVVGN LRQGTVALQE AQDTMQGTSR SLRLIQDRVA EVQQVLRPAE KLVTSMTKQL GDFWTRMEEL RHQARQQGAE AVQAQQLAEG ASEQALSAQE GFERIKQKYA ELKDRLGQSS MLGEQGARIQ SVKTEAEELF GETMEMMDRM KDMELELLRG SQAIMLRSAD LTGLEKRVEQ IRDHINGRVL YYATCK (828-1172 aa encoded by BC075838 )

Target Information

The product encoded by this gene is a laminin that belongs to a family of basement membrane proteins. This protein is a beta subunit laminin, which together with an alpha and a gamma subunit, forms laminin-5. Mutations in this gene cause epidermolysis bullosa junctional Herlitz type, and generalized atrophic benign epidermolysis bullosa, diseases that are characterized by blistering of the skin. Multiple alternatively spliced transcript variants that encode the same protein have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Tumor-derived extracellular vesicles delivering TNF-α promotes colorectal cancer metastasis via the NF-kB/LAMB3/AKT axis by targeting SNAP23.

Archives of biochemistry and biophysics

Xie BW,Guan B,Chen W,Zhou M,Gu Q,Liu Y,Yan D

Thu Jun 01 00:00:00 UTC 2023

Tumor-derived extracellular vesicles delivering TNF-α promotes colorectal cancer metastasis via the NF-kB/LAMB3/AKT axis by targeting SNAP23.

Archives of biochemistry and biophysics

Xie BW,Guan B,Chen W,Zhou M,Gu Q,Liu Y,Yan D

Thu Jun 01 00:00:00 UTC 2023

Tumor-derived extracellular vesicles delivering TNF-α promotes colorectal cancer metastasis via the NF-kB/LAMB3/AKT axis by targeting SNAP23.

Archives of biochemistry and biophysics

Xie BW,Guan B,Chen W,Zhou M,Gu Q,Liu Y,Yan D

Thu Jun 01 00:00:00 UTC 2023

hsa-mir-133a-2 promotes the proliferation and invasion of cervical cancer cells by targeting the LAMB3-mediated PI3K/ATK pathway.

Cancer medicine

Sui X,Sun Y,Zhang G,Chi N,Guan Y,Wang D,Li X

Wed Mar 01 00:00:00 UTC 2023

The LINC00623/NAT10 signaling axis promotes pancreatic cancer progression by remodeling ac4C modification of mRNA.

Journal of hematology & oncology

Feng Z,Li K,Qin K,Liang J,Shi M,Ma Y,Zhao S,Liang H,Han D,Shen B,Peng C,Chen H,Jiang L

Wed Aug 17 00:00:00 UTC 2022

Laminin‑332 mediates proliferation, apoptosis, invasion, migration and epithelial‑to‑mesenchymal transition in pancreatic ductal adenocarcinoma.

Molecular medicine reports

Huang C,Chen J

Fri Jan 01 00:00:00 UTC 2021

Senolytic therapy ameliorates renal fibrosis postacute kidney injury by alleviating renal senescence.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Li C,Shen Y,Huang L,Liu C,Wang J

Fri Jan 01 00:00:00 UTC 2021

Identification of Novel microRNA Profiles Dysregulated in Plasma and Tissue of Abdominal Aortic Aneurysm Patients.

International journal of molecular sciences

Plana E,Gálvez L,Medina P,Navarro S,Fornés-Ferrer V,Panadero J,Miralles M

Sun Jun 28 00:00:00 UTC 2020

MiR-24-3p Inhibits the Progression of Pancreatic Ductal Adenocarcinoma Through LAMB3 Downregulation.

Frontiers in oncology

Huang W,Gu J,Tao T,Zhang J,Wang H,Fan Y

Mon Sep 28 00:00:00 UTC 2020

MiR-24-3p Inhibits the Progression of Pancreatic Ductal Adenocarcinoma Through LAMB3 Downregulation.

Frontiers in oncology

Huang W,Gu J,Tao T,Zhang J,Wang H,Fan Y

Mon Sep 28 00:00:00 UTC 2020

Bioinformatics

Protein Aliases: Epiligrin subunit bata; Kalinin B1 chain; Kalinin subunit beta; kalinin-140kDa; Laminin B1k chain; laminin beta 3; laminin S B3 chain; Laminin subunit beta-3; laminin, beta 3 (nicein (125kD), kalinin (140kD), BM600 (125kD)); Laminin-5 subunit beta; Nicein subunit beta; nicein-125k; nicein-125kDa; RP1-272L16.3

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Gene Aliases: AI1A; BM600-125KDA; LAM5; LAMB3; LAMNB1

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UniProt ID: (Human) Q13751

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Entrez Gene ID: (Human) 3914

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Function(s)

structural molecule activity protein binding protein complex binding

Process(es)

cell adhesion epidermis development extracellular matrix disassembly extracellular matrix organization hemidesmosome assembly endodermal cell differentiation brown fat cell differentiation

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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LAMB3 Polyclonal Antibody

LAMB3 Antibody (26795-1-AP) in WB

Product Details

26795-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunocytochemistry (ICC/IF)

Species Reactivity

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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