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Positive Control:Human brain.
Cellular Location: Cell Surface. Lysosome.
Lysosome-associated membrane protein 5 (LAMP5) is a member of the LAMP family. LAMP5 differs from other LAMP family members in that its expression is more restricted and is referred to as brain and dendritic cell-associated LAMP-like molecule (BAD-LAMP). In humans, BAD-LAMP is expressed in post-natal neurons and non-activated plasmacytoid dendritic cells. Expression in neurons is localized to intracellular vesicles distributed in specific microdomains along neurites and may play a role in endocytosis. BAD-LAMP is localized to the endoplasmic reticulum-Golgi intermediate compartment (ERGIC) of plasmacytoid dendritic cells and is lost upon TLR activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: BAD-LAMP; brain and dendritic cell associated LAMP; Brain and dendritic cell-associated LAMP; Brain-associated LAMP-like protein; LAMP family protein C20orf103; LAMP-5; lysosomal-associated membrane protein family, member 5; Lysosome-associated membrane glycoprotein 5; Lysosome-associated membrane protein 5
Gene Aliases: BAD-LAMP; BADLAMP; C20orf103; LAMP-5; LAMP5; UNC-46
UniProt ID: (Human) Q9UJQ1
Entrez Gene ID: (Human) 24141
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