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Invitrogen
LAS1L Polyclonal Antibody
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Product Details
PA5-68646
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
synthetic peptide directed towards the middle region of human LAS1L
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2688669
Product Specific Information
This target displays homology in the following species: Cow: 79%; Horse: 85%; Human: 100%
Target Information
Involved in the biogenesis of the 60S ribosomal subunit. Required for maturation of the 28S rRNA. Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Endoribonuclease LAS1L; LAS1-like, ribosome biogenesis factor; Protein LAS1 homolog; Ribosomal biogenesis protein LAS1L
Gene Aliases: dJ475B7.2; Las1-like; LAS1L; MSTP060
UniProt ID: (Human) Q9Y4W2
Entrez Gene ID: (Human) 81887
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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